The Gliopeptide ODN, a Ligand for the Benzodiazepine Site of GABAA Receptors, Boosts Functional Recovery after Stroke

Autor: Julien Chuquet, Andrew N. Clarkson, Ann-Britt Marcher, Katarzyna Gach-Janczak, Mahmoud Hazime, David Vaudry, Julie Maucotel, Katia Lehongre, Benjamin Lefranc, Pascale P. Quilichini, Raghavendra Y. Nagaraja, Emma K. Gowing, Susanne Mandrup, Rhita Lamtahri, Jérôme Leprince, Michael Alasoadura

Publikováno v: Lamtahri, R, Hazime, M, Gowing, E K, Nagaraja, R Y, Maucotel, J, Alasoadura, M, Quilichini, P P, Lehongre, K, Lefranc, B, Gach-Janczak, K, Marcher, A B, Mandrup, S, Vaudry, D, Clarkson, A N, Leprince, J & Chuquet, J 2021, ' The gliopeptide ODN, a ligand for the benzodiazepine site of GABA A receptors, boosts functional recovery after stroke ', Journal of Neuroscience, vol. 41, no. 33, pp. 7148-7159 . https://doi.org/10.1523/JNEUROSCI.2255-20.2021
Journal of Neuroscience
Journal of Neuroscience, 2021, 41 (33), pp.7148-7159. ⟨10.1523/JNEUROSCI.2255-20.2021⟩

Following stroke, the survival of neurons and their ability to re-establish connections is critical to functional recovery. This is strongly influenced by the balance between neuronal excitation and inhibition. In the acute phase of experimental stro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25649e49dc0582c0ff69b132fd0af09a
https://doi.org/10.1523/jneurosci.2255-20.2021

Glial Endozepines Reverse High-Fat Diet-Induced Obesity by Enhancing Hypothalamic Response to Peripheral Leptin

Autor: Guenievre Roussel, Bruno Lebrun, Vincent Prevot, Michel Dallaporta, Marie-Christine Tonon, Damien Lanfray, André Jean, Manon Duquenne, Florent Guillebaud, Jean-Denis Troadec, Seddik Riad, Mehdi Djelloul, Jérôme Leprince, Clément Pierre, Kevin Poirot, Stéphanie Gaigé, Fabrice Morin

Publikováno v: Molecular Neurobiology
Molecular Neurobiology, Humana Press, 2020, ⟨10.1007/s12035-020-01944-z⟩
Molecular Neurobiology, 2020, ⟨10.1007/s12035-020-01944-z⟩

Research on energy homeostasis has focused on neuronal signaling; however, the role of glial cells has remained little explored. Glial endozepines exert anorexigenic actions by mechanisms which remain poorly understood. In this context, the present s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c0139b8975ec81f05b74b51848d0f0
https://doi.org/10.1007/s12035-020-01944-z

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Neuroprotection with the Endozepine Octadecaneuropeptide, ODN

Autor: Marie-Christine Tonon, Yosra Hamdi, Jérôme Leprince, Olfa Masmoudi-Kouki, Hubert Vaudry, Ikram Ghouili, Hadhemi Kaddour, Hélène Castel, Seyma Bahdoudi, Mohamed Amri, David Vaudry

Publikováno v: Current Pharmaceutical Design
Current Pharmaceutical Design, Bentham Science Publishers, 2018, 24 (33), pp.3918-3925. ⟨10.2174/1381612824666181112111746⟩

International audience; The term endozepines designates a family of astroglia-secreted proteins including the diazepambinding inhibitor (DBI) and its processing products, which have been originally isolated and characterized as endogenous ligands of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca4ea13d038127d06453f257a8c1a60d
https://hal-normandie-univ.archives-ouvertes.fr/hal-02280075