Role of endothelial cells in graft-versus-host disease

Autor: Lotus Neidemire-Colley, Jérémy Robert, Antoine Ackaoui, Adrienne M. Dorrance, Martin Guimond, Parvathi Ranganathan

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

To date, the only curative treatment for high-risk or refractory hematologic malignancies non-responsive to standard chemotherapy is allogeneic hematopoietic transplantation (allo-HCT). Acute graft-versus-host disease (GVHD) is a donor T cell-mediate

Externí odkaz: https://doaj.org/article/1df630b4376b4178bf619ffde8a3bb68

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The regulation of vascular tetrahydrobiopterin bioavailability

Autor: Anna Starr, Manasi Nandi, Dania Hussein

Publikováno v: Starr, A, Hussein, D & Nandi, M 2013, ' The regulation of vascular tetrahydrobiopterin bioavailability ', VASCULAR PHARMACOLOGY, vol. 58, no. 3, pp. 219-230 . https://doi.org/10.1016/j.vph.2012.08.002

6R l-erythro-5,6,7,8-tetrahydrobiopterin (BH4) is an essential cofactor for several enzymes including phenylalanine hydroxylase and the nitric oxide synthases (NOS). Oral supplementation of BH4 has been successfully employed to treat subsets of patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2efefff481cf05cd434ac7b1cc41df
https://pubmed.ncbi.nlm.nih.gov/23634439

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