Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Endosome lumen"'
Publikováno v:
The Journal of Neuroscience
Loss-of-function mutations in endosomal Na+/H+exchanger 6 (NHE6) cause the X-linked neurologic disorder Christianson syndrome. Patients exhibit symptoms associated with both neurodevelopmental and neurodegenerative abnormalities. While loss of NHE6 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93d566d8fefcb4bf080d399543adcf4a
https://doi.org/10.1523/jneurosci.1244-20.2021
https://doi.org/10.1523/jneurosci.1244-20.2021
Autor:
Jung-Hyun Yang, Seong Hoon Kim, Tong Yi Jin, Young-Bum Yoo, Kyoung Sik Park, Ik-Jin Yun, Madhuri Saindane, Sang-Eun Nam
Publikováno v:
Medicine
Purpose Obesity strongly affects the prognosis of various malignancies, including breast cancer. Leptin (LEP) may be associated with obesity and breast cancer prognosis. The purpose of our study was to determine the prognostic value of LEP in breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::288bcc1623aebfc9b8a29aba2d572150
https://doi.org/10.1097/md.0000000000026896
https://doi.org/10.1097/md.0000000000026896
Autor:
Mohamed A. Hamood, Daniela M. Gomez Zubieta, Kalyan C. Kondapalli, Rami Beydoun, Ashley E. Pall
Publikováno v:
Cell Communication and Signaling : CCS
Cell Communication and Signaling, Vol 15, Iss 1, Pp 1-12 (2017)
Cell Communication and Signaling, Vol 15, Iss 1, Pp 1-12 (2017)
Background Glioblastoma multiformae (GBM) is the most aggressive type of malignant brain tumor with complex molecular profile. Overexpression of Na+/H+ Exchanger isoform 9 (NHE9) promotes tumor progression and correlates positively with insensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8e728458dc4447986add431df414bc
http://europepmc.org/articles/PMC5740897
http://europepmc.org/articles/PMC5740897
Autor:
Alexey J. Merz, Daniel P. Nickerson
Publikováno v:
Traffic. 16:1318-1329
Endosomes are transportation nodes, mediating selective transport of soluble and transmembrane cargos to and from the Golgi apparatus, plasma membrane and lysosomes. As endosomes mature to become multivesicular bodies (MVBs), Endosomal Sorting Comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99a61c435690535202fea33003625733
https://doi.org/10.1111/tra.12331
https://doi.org/10.1111/tra.12331
Autor:
Anjon Audhya, E. B. Frankel
Publikováno v:
Seminars in celldevelopmental biology. 74
The endosomal sorting complex required for transport (ESCRT) machinery is composed of five multi-subunit protein complexes, which act cooperatively at specialized endosomes to facilitate the movement of specific cargoes from the limiting membrane int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::392310be44e3b31e144ca458eb0597da
https://pubmed.ncbi.nlm.nih.gov/28797838
https://pubmed.ncbi.nlm.nih.gov/28797838
Endosomophagy clears disrupted early endosomes but not virus particles during virus entry into cells
Autor:
Vibhu Prasad, Michael Bauer, Maarit Suomalainen, Urs F. Greber, Silvio Hemmi, Stefania Luisoni, Hemmo Meyer, Chrisovalantis Papadopoulos, Karin Boucke
Publikováno v:
Matters.
Enveloped viruses fuse with host membranes without affecting cell integrity. Non-enveloped viruses and bacteria penetrate by rupturing endosomal membranes, and thereby expose complex-type carbohydrates from the endosome lumen to cytosolic proteins. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41cbac155d9e9c28dba60fc6d380c329
https://doi.org/10.19185/matters.201606000013
https://doi.org/10.19185/matters.201606000013
Publikováno v:
Molecular Biology of the Cell
Disassembly of ESCRT-III requires Vps4 ATPase activity under the control of regulatory proteins. Described here are distinct spatiotemporal functions for Vps4 regulators, with Did2 playing a unique role in regulating MVB lumenal vesicle size and Vtal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f05e1d0d73ba10d7ef22ba107a09709
https://doi.org/10.1091/mbc.e09-09-0776
https://doi.org/10.1091/mbc.e09-09-0776
Publikováno v:
The Journal of Cell Biology
The sorting of transmembrane cargo proteins into the lumenal vesicles of multivesicular bodies (MVBs) depends on the recruitment of endosomal sorting complexes required for transport (ESCRTs) to the cytosolic face of endosomal membranes. The subseque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bcf6ba042beb728ae73add61cd42c07
http://europepmc.org/articles/PMC2064671
http://europepmc.org/articles/PMC2064671
Publikováno v:
Journal of Biological Chemistry. 279:18270-18276
The endosome-associated protein Hrs inhibits the homotypic fusion of early endosomes. A helical region of Hrs containing a Q-SNARE motif mediates this effect as well as its endosomal membrane association via SNAP-25, an endosomal receptor for Hrs. Hr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2d0df5ec9eb5da3a6e55e042a7c2b7
https://doi.org/10.1074/jbc.m400093200
https://doi.org/10.1074/jbc.m400093200
Autor:
Linda A Hicke, Rebecca Dunn
Publikováno v:
Annual Review of Cell and Developmental Biology. 19:141-172
▪ Abstract Ubiquitin regulates protein transport between membrane compartments by serving as a sorting signal on protein cargo and by controlling the activity of trafficking machinery. Monoubiquitin attached to integral plasma membrane proteins or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e4c2b745ff0972460ac89cc3eb0042d
https://doi.org/10.1146/annurev.cellbio.19.110701.154617
https://doi.org/10.1146/annurev.cellbio.19.110701.154617