Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Endoplasmic Reticulum/metabolism"'
Autor:
Hector Foronda, Yangxue Fu, Adriana Covarrubias-Pinto, Hartmut T. Bocker, Alexis González, Eric Seemann, Patricia Franzka, Andrea Bock, Ramachandra M. Bhaskara, Lutz Liebmann, Marina E. Hoffmann, Istvan Katona, Nicole Koch, Joachim Weis, Ingo Kurth, Joseph G. Gleeson, Fulvio Reggiori, Gerhard Hummer, Michael M. Kessels, Britta Qualmann, Muriel Mari, Ivan Dikić, Christian A. Hübner
Publikováno v:
Nature
Foronda, H, Fu, Y, Covarrubias-Pinto, A, Bocker, H T, González, A, Seemann, E, Franzka, P, Bock, A, Bhaskara, R M, Liebmann, L, Hoffmann, M E, Katona, I, Koch, N, Weis, J, Kurth, I, Gleeson, J G, Reggiori, F, Hummer, G, Kessels, M M, Qualmann, B, Mari, M, Dikić, I & Hübner, C A 2023, ' Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy ', Nature, vol. 618, no. 7964, pp. 402-410 . https://doi.org/10.1038/s41586-023-06090-9
Foronda, H, Fu, Y, Covarrubias-Pinto, A, Bocker, H T, González, A, Seemann, E, Franzka, P, Bock, A, Bhaskara, R M, Liebmann, L, Hoffmann, M E, Katona, I, Koch, N, Weis, J, Kurth, I, Gleeson, J G, Reggiori, F, Hummer, G, Kessels, M M, Qualmann, B, Mari, M, Dikić, I & Hübner, C A 2023, ' Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy ', Nature, vol. 618, no. 7964, pp. 402-410 . https://doi.org/10.1038/s41586-023-06090-9
Membrane-shaping proteins characterized by reticulon homology domains play an important part in the dynamic remodelling of the endoplasmic reticulum (ER). An example of such a protein is FAM134B, which can bind LC3 proteins and mediate the degradatio
Autor:
van Leeuwen, Wessel, Nguyen, Dan T M, Grond, Rianne, Veenendaal, Tineke, Rabouille, Catherine, Farías, Ginny G, Celbiologie, Sub Cell Biology
Publikováno v:
Journal of Cell Science, 135(23). Company of Biologists Ltd
Journal of Cell Science, 135(23). COMPANY OF BIOLOGISTS LTD
Journal of Cell Science, 135(23). COMPANY OF BIOLOGISTS LTD
Phase separation of ER-exit-sites (ERES) components into membraneless compartments, the Sec bodies, occurs in Drosophila cells upon specific cellular stressors, i.e., salt stress and amino acid starvation, and their formation is linked to the inhibit
Autor:
Verweij, Frederik, Bebelman, Maarten P, George, Anna, Couty, Mickael, Bécot, Anaïs, Palmulli, Roberta, Heiligenstein, Xavier, Sires-Campos, Julia, Raposo, Graca, Pegtel, Dirk Michiel, Van Niel, Guillaume, Sub Cell Biology, Celbiologie
Publikováno v:
The Journal of cell biology, 221(12):e202112032, 1-18. Rockefeller University Press
Verweij, F J, Bebelman, M P, George, A E, Couty, M, Bécot, A, Palmulli, R, Heiligenstein, X, Sirés-Campos, J, Raposo, G, Pegtel, D M & van Niel, G 2022, ' ER membrane contact sites support endosomal small GTPase conversion for exosome secretion ', Journal of Cell Biology, vol. 221, no. 12, e202112032 . https://doi.org/10.1083/jcb.202112032
Verweij, F J, Bebelman, M P, George, A E, Couty, M, Bécot, A, Palmulli, R, Heiligenstein, X, Sirés-Campos, J, Raposo, G, Pegtel, D M & van Niel, G 2022, ' ER membrane contact sites support endosomal small GTPase conversion for exosome secretion ', The Journal of cell biology, vol. 221, no. 12, e202112032, pp. 1-18 . https://doi.org/10.1083/jcb.202112032
Journal of Cell Biology, 221(12):e202112032. Rockefeller University Press
Journal of Cell Biology, 221(12), 1. Rockefeller University Press
Verweij, F J, Bebelman, M P, George, A E, Couty, M, Bécot, A, Palmulli, R, Heiligenstein, X, Sirés-Campos, J, Raposo, G, Pegtel, D M & van Niel, G 2022, ' ER membrane contact sites support endosomal small GTPase conversion for exosome secretion ', Journal of Cell Biology, vol. 221, no. 12, e202112032 . https://doi.org/10.1083/jcb.202112032
Verweij, F J, Bebelman, M P, George, A E, Couty, M, Bécot, A, Palmulli, R, Heiligenstein, X, Sirés-Campos, J, Raposo, G, Pegtel, D M & van Niel, G 2022, ' ER membrane contact sites support endosomal small GTPase conversion for exosome secretion ', The Journal of cell biology, vol. 221, no. 12, e202112032, pp. 1-18 . https://doi.org/10.1083/jcb.202112032
Journal of Cell Biology, 221(12):e202112032. Rockefeller University Press
Journal of Cell Biology, 221(12), 1. Rockefeller University Press
Exosomes are endosome-derived extracellular vesicles involved in intercellular communication. They are generated as intraluminal vesicles within endosomal compartments that fuse with the plasma membrane (PM). The molecular events that generate secret
Autor:
Wim Annaert, Katleen Dillen, Randy Schekman, Ragna Sannerud, Bertrand Kleizen, Rosanne Wouters, David Demedts, Christine Michiels, Abril Escamilla Ayala, Wendy Vermeire
Publikováno v:
Journal of Cell Biology, 220(9), 1. Rockefeller University Press
γ-Secretase affects many physiological processes through targeting >100 substrates; malfunctioning links γ-secretase to cancer and Alzheimer's disease. The spatiotemporal regulation of its stoichiometric assembly remains unresolved. Fractionation,
Autor:
Wouters, Rosanne, Michiels, Christine, Sannerud, Ragna, Kleizen, Bertrand, Dillen, Katleen, Vermeire, Wendy, Ayala, Abril, Demedts, David, Annaert, Wim, SCHEKMAN, Randy W
Publikováno v:
The Journal of Cell Biology, vol 220, iss 9
γ-Secretase affects many physiological processes through targeting >100 substrates; malfunctioning links γ-secretase to cancer and Alzheimers disease. The spatiotemporal regulation of its stoichiometric assembly remains unresolved. Fractionation, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f2ae0199a715d64c89f2a0ccb4aace5c
https://dspace.library.uu.nl/handle/1874/414000
https://dspace.library.uu.nl/handle/1874/414000
Autor:
Yoan, Arribat, Dogan, Grepper, Sylviane, Lagarrigue, Timothy, Qi, Sarah, Cohen, Francesca, Amati
Publikováno v:
PLoS genetics, vol. 16, no. 4, pp. e1008665
PLoS Genetics, Vol 16, Iss 4, p e1008665 (2020)
PLoS Genetics
PLoS Genetics, Vol 16, Iss 4, p e1008665 (2020)
PLoS Genetics
Lipid droplets (LD) are affected in multiple human disorders. These highly dynamic organelles are involved in many cellular roles. While their intracellular dispersion is crucial to ensure their function and other organelles-contact, underlying mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::31e2505295f772ada5256926dd563a94
https://serval.unil.ch/notice/serval:BIB_A8167CF70446
https://serval.unil.ch/notice/serval:BIB_A8167CF70446
Publikováno v:
Methods in molecular biology, 2128
Diabetes is a major public health problem: it is estimated that 420 million people are affected globally. Monogenic forms of diabetes are less common, but variants in monogenic diabetes genes have been shown to contribute to type 2 diabetes risk. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2101::4bc2c2ed6eba9b9fa8087714a0573669
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/326378
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/326378
Publikováno v:
The Journal of Biological Chemistry
Heat shock 70 kDa protein (Hsp70) chaperones play a crucial role in the biogenesis of tail-anchored proteins (TAs), starting a downstream cascade to the endoplasmic reticulum (ER) via the guided-entry-of-tail-anchored protein (GET) pathway. J-domain
Autor:
Raquel Seruca, Joao Sanches, Joana Figueiredo, Soraia Melo, Kimberley Gamet, Susana Seixas, Parry Guilford, Tanis D Godwin
Publikováno v:
Molecular Cancer
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Molecular Cancer, Vol 17, Iss 1, Pp 1-7 (2018)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Molecular Cancer, Vol 17, Iss 1, Pp 1-7 (2018)
The aim of this study was to uncover the pathogenic relevance and the underlying molecular mechanism of a novel CDH1 variant found in a Hereditary Diffuse Gastric Cancer family (p.L13_L15del), which affects the signal peptide of E-cadherin without ch
Autor:
Martinon, F.
Publikováno v:
Joint, bone, spine, vol. 85, no. 4, pp. 423-428
Key cellular functions including those related to energy metabolism, organization of the genetic information or production of membrane-bound and secreted proteins are compartmentalized within organelles. Various stresses such as differentiation progr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1900::18df525ac2a5e3128929df97acae4c3b
https://serval.unil.ch/resource/serval:BIB_18E9EB64E09E.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_18E9EB64E09E.P001/REF.pdf