Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Endocytosi"'
Publikováno v:
Journal of cellular physiology. 237(10)
Genetic studies support the amyloid cascade as the leading hypothesis for the pathogenesis of Alzheimer's disease (AD). Although significant efforts have been made in untangling the amyloid and other pathological events in AD, ongoing interventions f
Autor:
KARIMBAYLI, JAVAD
High Grade Epithelial Ovarian Cancers (HGEOCs) is a heterogeneous group of tumours. Late diagnosis and drug-resistant recurrences make HGEOCs the most lethal gynaecological malignancy. The central role played by Cyclin-Dependent Kinases (CDKs), in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::91089b6c47fcf398e0e7171052690b3c
http://hdl.handle.net/11368/3014979
http://hdl.handle.net/11368/3014979
Autor:
Antonella Accardo, Elisabetta Rosa, Carlo Diaferia, Giovanni Smaldone, Enrico Gallo, Giancarlo Morelli
Publikováno v:
International Journal of Nanomedicine
International Journal of Nanomedicine, Vol Volume 16, Pp 1617-1630 (2021)
International Journal of Nanomedicine, Vol Volume 16, Pp 1617-1630 (2021)
Enrico Gallo,1 Carlo Diaferia,2 Elisabetta Rosa,2 Giovanni Smaldone,1 Giancarlo Morelli,2 Antonella Accardo2 1IRCCS SDN, Naples, 80143, Italy; 2Department of Pharmacy and Research Centre on Bioactive Peptides (CIRPeB), University of Naples “Federic
Autor:
Maria Laura Bolognesi, Marina Naldi, Sabrina Petralla, Claudia Albertini, Barbara Monti, Manuela Bartolini, Daniela Grifoni, Silvia Strocchi
Publikováno v:
Molecules
Volume 26
Issue 4
Molecules, Vol 26, Iss 1112, p 1112 (2021)
Volume 26
Issue 4
Molecules, Vol 26, Iss 1112, p 1112 (2021)
Despite Alzheimer’s disease (AD) incidence being projected to increase worldwide, the drugs currently on the market can only mitigate symptoms. Considering the failures of the classical paradigm “one target-one drug-one disease” in delivering e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa954cf3574dca02f20761e8fbd9d4b
http://hdl.handle.net/11585/843407
http://hdl.handle.net/11585/843407
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
mBio
mBio
Direct cell-to-cell spreading of Listeria monocytogenes requires the bacteria to induce actin-based finger-like membrane protrusions in donor host cells that are endocytosed through caveolin-rich membrane invaginations by adjacent receiving cells. An
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05784d6fcbd6f6d5ce7c046ebae65e94
https://hdl.handle.net/10281/396254
https://hdl.handle.net/10281/396254
Autor:
Roberta Romano, Eeva-Liisa Eskelinen, Cristina Rivellini, Raffaella Beli, Fiore Manganelli, Stefano C. Previtali, Rossana Tonlorenzi, Maria De Luca, Maria Nolano, Cecilia Bucci, Lucio Santoro
Publikováno v:
Cellular and Molecular Life Sciences
The small GTPase RAB7A regulates late stages of the endocytic pathway and plays specific roles in neurons, controlling neurotrophins trafficking and signaling, neurite outgrowth and neuronal migration. Mutations in the RAB7A gene cause the autosomal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a6cf8b56c146a39a01e391f5dc0518
http://hdl.handle.net/11588/803117
http://hdl.handle.net/11588/803117
Autor:
Gaetano Napoli, Alain Goriely
Endocytosis and exocytosis are key mechanisms in cellular systems by which a cell deforms its plasma membrane to move substances in or out of the cell. Whereas these cellular processes typically rely on active mechanisms, we study here the problem of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f766c9be9ca4dce4b667d729b8517be
https://doi.org/10.1016/j.jmps.2020.104133
https://doi.org/10.1016/j.jmps.2020.104133
Autor:
Veronica Nisi, Franco Taroni, Cecilia Bucci, Tiziana Cavallaro, Maria De Luca, Giuseppe Lauria, Stefania Magri, James M. Polke, Roberta Romano, Davide Pareyson, Raffaella Lombardi, Giuseppe Piscosquito, Mary M. Reilly, Paola Fossa, Chiara Pisciotta, Elena Cichero, Gian Maria Fabrizi, Paola Saveri
Publikováno v:
Cells
Cells, Vol 9, Iss 1028, p 1028 (2020)
Volume 9
Issue 4
Cells, Vol 9, Iss 1028, p 1028 (2020)
Volume 9
Issue 4
The rare autosomal dominant Charcot-Marie-Tooth type 2B (CMT2B) is associated with mutations in the RAB7A gene, involved in the late endocytic pathway. CMT2B is characterized by predominant sensory loss, ulceromutilating features, with lesser-to-abse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4f59b1afd04aa42cfcbb66e670df2f
https://hdl.handle.net/11587/447144
https://hdl.handle.net/11587/447144
Autor:
Silva Hećimović, Cecilia Bucci, Rom Paz, Kristina Dominko, Hagit Eldar-Finkelman, Limor Avrahami
Publikováno v:
Cellular signalling
Impaired lysosomal activity, which results in defective protein processing, waste accumulation, and protein aggregation, is implicated in a number of disease pathologies. Acidification of lysosomes is a crucial process required for lysosome function.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76847f8f0157c8f7b50b8c958ab73454
https://hdl.handle.net/11587/436498
https://hdl.handle.net/11587/436498
Publikováno v:
Microbial Cell, Vol 5, Iss 11, Pp 482-494 (2018)
All proliferating cells need to match metabolism, growth and cell cycle progression with nutrient availability to guarantee cell viability in spite of a changing environment. In yeast, a signaling pathway centered on the effector kinase Snf1 is requi