Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Endika Martín-Encinas"'
Autor:
Endika Martín-Encinas, María Fuertes, Samuel Delgado-Hernández, Fernando García-Tellado, David Tejedor, Concepción Alonso
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
This work explores the biological evaluation of novel cyanomethyl vinyl ether derivatives as antiproliferative agents. Tubulin, crucial to microtubule structure and function, is a target for cancer therapies. In vitro cytotoxicity assessments reveale
Externí odkaz:
https://doaj.org/article/849db96aafa443d2b093fc7f1ece9c03
Autor:
Estela Melcón-Fernandez, Endika Martín-Encinas, Francisco Palacios, Gulio Galli, Rosa M. Reguera, María Martínez-Valladares, Rafael Balaña-Fouce, Concepción Alonso, Yolanda Pérez-Pertejo
Publikováno v:
Molecules, Vol 29, Iss 1, p 74 (2023)
In the absence of a vaccine, there is a need to find new drugs for the treatment of neglected tropical diseases, such as leishmaniasis, that can overcome the many drawbacks of those currently used. These disadvantages include cost, the need to mainta
Externí odkaz:
https://doaj.org/article/5d63836c7a114f4dba0a8c801602e18a
Autor:
Endika Martín Encinas, Leyre Lopez-Aguileta, Concepción Alonso, Francisco Palacios, Asier Selas
Publikováno v:
EKAIA Euskal Herriko Unibertsitateko Zientzia eta Teknologia Aldizkaria.
LABURPENA: Minbizia heriotz-eragile nagusienen artean azaltzen da mundu mailan, 2020an 10 milioi heriotz inguru gauzatu zituena. Minbiziaren aurkako tratamendu farmakologikoari dagokionez, agente kimioterapiko eraginkorrenen artean, topoisomerasa I (
Publikováno v:
Expert opinion on drug discovery. 17(6)
Cancer has been identified as one of the leading causes of death worldwide. The biological target of some anticancer agents is topoisomerase I, an enzyme involved in the relaxation of supercoiled DNA. The synthesis of new compounds with antiprolifera
Autor:
Marcelle D. Perretti, Yaiza Pérez-Pérez, Kevin Soler-Carracedo, Endika Martín-Encinas, Concepción Alonso, Jimena Scoccia, Romen Carrillo
Publikováno v:
Addi. Archivo Digital para la Docencia y la Investigación
instname
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Dynamic nucleophilic aromatic substitution of tetrazines (SNTz) has been employed to build theranostic prodrugs that are activated by hydrogen sulfide. H2S is typically found in high concentrations in some kinds of cancer cells and it is able to trig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7d2d3f948c08df48211d8686920a58
http://hdl.handle.net/10810/56467
http://hdl.handle.net/10810/56467
Autor:
Endika Martín-Encinas, Rafael E. Paiva-Feener, Tanausú Santos, Romen Carrillo, David S. Rivero
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
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Dynamic nucleophilic aromatic substitution of tetrazines (SNTz) has been used for the synthesis of dynamic covalent polymer networks that take advantage of both the reversible nature of the reaction and the versatility of the tetrazine ring. Polymer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b3684f201903a9f0a27bfe2a0e1df6
http://hdl.handle.net/10261/254734
http://hdl.handle.net/10261/254734
Autor:
Endika Martín-Encinas, Jorge Pasán, David S Rivero, Antonio Hernández Daranas, Tanausú Santos, Yaiza Pérez-Pérez, Romen Carrillo
Publikováno v:
Angewandte Chemie (International Ed. in English)
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
A dynamic nucleophilic aromatic substitution of tetrazines (SNTz) is presented herein. It combines all the advantages of dynamic covalent chemistry with the versatility of the tetrazine moiety. Indeed, libraries of compounds or sophisticated molecula
Autor:
Melcón-Fernandez, Estela1 (AUTHOR) ggal@unileon.es, Martín-Encinas, Endika2 (AUTHOR), Palacios, Francisco2 (AUTHOR), Galli, Gulio1 (AUTHOR), Reguera, Rosa M.1 (AUTHOR), Martínez-Valladares, María1 (AUTHOR), Balaña-Fouce, Rafael1 (AUTHOR), Alonso, Concepción2 (AUTHOR) concepcion.alonso@ehu.eus, Pérez-Pertejo, Yolanda1 (AUTHOR) concepcion.alonso@ehu.eus
Publikováno v:
Molecules. Jan2024, Vol. 29 Issue 1, p74. 16p.
Autor:
Santos, Tanausú1 (AUTHOR), Rivero, David S.1 (AUTHOR), Pérez‐Pérez, Yaiza1 (AUTHOR), Martín‐Encinas, Endika1 (AUTHOR), Pasán, Jorge2 (AUTHOR), Daranas, Antonio Hernández1 (AUTHOR), Carrillo, Romen1 (AUTHOR) rcarrillo@ipna.csic.es
Publikováno v:
Angewandte Chemie. 8/16/2021, Vol. 133 Issue 34, p18931-18939. 9p.
Autor:
Alonso, Concepción1, Martín‐Encinas, Endika1, Rubiales, Gloria1, Palacios, Francisco1 francisco.palacios@ehu.eus
Publikováno v:
European Journal of Organic Chemistry. 5/26/2017, Vol. 2017 Issue 20, p2916-2924. 9p. 3 Charts.