Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Enda W. McDermott"'
Autor:
Jasper Wouters, Miguel Vizoso, Anna Martinez-Cardus, F. Javier Carmona, Olivier Govaere, Teresa Laguna, Jesuchristopher Joseph, Peter Dynoodt, Claudia Aura, Mona Foth, Roy Cloots, Karin van den Hurk, Balazs Balint, Ian G. Murphy, Enda W. McDermott, Kieran Sheahan, Karin Jirström, Bjorn Nodin, Girish Mallya-Udupi, Joost J. van den Oord, William M. Gallagher, Manel Esteller
Publikováno v:
BMC Medicine, Vol 15, Iss 1, Pp 1-16 (2017)
Abstract Background Cutaneous melanoma is the deadliest skin cancer, with an increasing incidence and mortality rate. Currently, staging of patients with primary melanoma is performed using histological biomarkers such as tumor thickness and ulcerati
Externí odkaz:
https://doaj.org/article/c8d582e4e15a4836ac917268c4fb77a8
Publikováno v:
Tumor Biology, Vol 40 (2018)
Biomarkers are the key to personalized treatment in patients with breast cancer. While tissue biomarkers are most useful in determining prognosis and upfront predicting response to therapy, circulating protein biomarkers such as CA 15-3 and carcinoem
Externí odkaz:
https://doaj.org/article/66b21659be454154a3875360a7baa41e
Autor:
Denis Evoy, Jane Rothwell, James Geraghty, Damian McCartan, Ruth Prichard, Amber Shrestha, Ahmed Al Maksoud, Enda W. McDermott, Carolyn Cullinane
Publikováno v:
European Journal of Surgical Oncology. 47:1507-1513
Administration of chemotherapy before breast surgery has the potential to reduce the risk of distant recurrence by targeting micrometastasis as well as allowing a more minimalistic approach to surgical intervention. We performed a systematic review t
Autor:
J M Walshe, Damian McCartan, Enda W. McDermott, Jane Rothwell, James Geraghty, F Al Rahbi, Cecily Quinn, L.M. Smyth, Maccon M. Keane, Ruth Prichard, Mehala Tharmabala, K McSorley, John Crown, Steve Millen, Lynda M McSorley, M J Kennedy, Catherine M. Kelly, Denis Evoy, S Chew, Seamus O'Reilly
Publikováno v:
Breast Cancer Research and Treatment. 188:789-798
Results from TAILOR-X suggest that up to 70% of hormone receptor-positive (HR+) node-negative (N0) ESBC patients (pts) may avoid chemotherapy (CT) with RS ≤ 25. We assess clinical and economic impacts of RS testing on treatment using real-world dat
Autor:
Prichard Ruth, Janice M. Walshe, Evoy Denis, Catherine M. Kelly, Damian McCartan, James Geraghty, John Crown, Maccon M. Keane, Fathiya Al Rahbi, Cecily Quinn, John James Kennedy, Mehala Tharmabala, Steve Millen, Lynda M. McSorley, Enda W. McDermott, Rothwell Jane, Seamus O'Reilly, L.M. Smyth
Publikováno v:
Cancer Research. 81:PS4-23
Background: The use of the 21-gene recurrence score assay (RS) has reduced chemotherapy (CT) administration in patients with hormone receptor (HR)-positive, HER-2 negative, lymph-node negative, early stage breast cancer (ESBC). Invasive lobular carci
Autor:
Carolyn, Cullinane, Hannah, Gillan, James, Geraghty, Denis, Evoy, Jane, Rothwell, Damian, McCartan, Enda W, McDermott, Ruth S, Prichard
Publikováno v:
BJS Open. 6
Background The significance of exogenous hormone manipulation as part of fertility treatment and its relationship to the development of breast cancer remains uncertain. Several historical reviews have been performed with conflicting results. This stu
Publikováno v:
British Journal of Surgery. 108
Background Since the ACOSOG Z0011 trial, rates of axillary node clearance (ANC) for micrometastatic axillary disease have declined among women undergoing breast conservation surgery (BCS). However, for women undergoing mastectomy, it remains unclear
Autor:
Boland, Ishwarya Balasubramanian, James Geraghty, Enda W. McDermott, Damian McCartan, S Doyle, Denis Evoy, G Hanley, R. S. Prichard
Publikováno v:
British Journal of Surgery. 108
Introduction Recent studies have suggested that sentinel lymph node biopsy (SLNB) can be omitted in newly diagnosed elderly breast cancer (BC) patients as it may not influence decisions regarding further therapeutic intervention. The aim of this stud
Autor:
Denis Evoy, Stephen J. Skehan, Éanna J Ryan, Michael R. Boland, Ruth Prichard, Damian McCartan, James Geraghty, Enda W. McDermott, Qurat Ain, Helen M. Heneghan
Publikováno v:
The Breast Journal. 26:1452-1454
Autor:
Jane Rothwell, James Geraghty, Luke Harrington, Ruth Prichard, Denis Evoy, Ann O'Doherty, Gavin Kane, Damian McCartan, Christina A Fleming, Fionn Nally, Robert Trueick, Cecily Quinn, Philip James, Enda W. McDermott, Sorcha McNally, Helen M. Heneghan
Publikováno v:
The Breast Journal. 25:848-852
Axillary nodal status remains an important determinant of prognosis and of the therapeutic strategy in patients with a newly diagnosed breast cancer. The aim of this study was to assess the false-negative rate of ultrasound (US)-guided fine-needle as