Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Enda Shevlin"'
Autor:
Enda Shevlin, Sinéad M Miggin
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107141 (2014)
Toll-like receptor 7 (TLR7) plays a vital role in the immune response to ssRNA viruses such as human rhinovirus (HRV) and Influenza, against which there are currently no treatments or vaccines with long term efficacy available. Clearly, a more compre
Externí odkaz:
https://doaj.org/article/0c53c1b58f184e4889d49ef5654bbdae
Autor:
Irene M. Min, Moonsoo M. Jin, Thomas J. Fahey, Rasa Zarnegar, Andrew B. Tassler, Theresa Scognamiglio, Paul J. Christos, Dessislava Stefanova, Heng Liang, Timothy M. Ullmann, Marjan Zaman, Enda Shevlin, Yanping Yang, Steve El Eshaky, Olivia R. Kalloo, Yogindra Vedvyas, Jaclyn E. McCloskey, Katherine D. Gray
A model for ICAM1-CAR T and anti-PD1 antibody activities in advanced thyroid cancers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fefdcd8131bc1ba4b4da4a1393ef4da
https://doi.org/10.1158/1078-0432.22476350
https://doi.org/10.1158/1078-0432.22476350
Data from PD1 Blockade Enhances ICAM1-Directed CAR T Therapeutic Efficacy in Advanced Thyroid Cancer
Autor:
Irene M. Min, Moonsoo M. Jin, Thomas J. Fahey, Rasa Zarnegar, Andrew B. Tassler, Theresa Scognamiglio, Paul J. Christos, Dessislava Stefanova, Heng Liang, Timothy M. Ullmann, Marjan Zaman, Enda Shevlin, Yanping Yang, Steve El Eshaky, Olivia R. Kalloo, Yogindra Vedvyas, Jaclyn E. McCloskey, Katherine D. Gray
Purpose:Advanced thyroid cancers, including poorly differentiated and anaplastic thyroid cancer (ATC), are lethal malignancies with limited treatment options. The majority of patients with ATC have responded poorly to programmed death 1 (PD1) blockad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b892ec492b9e25c8510c7cc3249031
https://doi.org/10.1158/1078-0432.c.6529379
https://doi.org/10.1158/1078-0432.c.6529379
Autor:
Moonsoo M. Jin, Thomas J. Fahey, Rasa Zarnegar, Andrew B. Tassler, Katherine D. Gray, Suraj Panjwani, Spencer Park, Susan Park, Weibin Wang, Maureen D. Moore, Theresa Scognamiglio, Brian Wyrwas, Marjan Zaman, Yogindra Vedvyas, Enda Shevlin, Irene M. Min
Figure S1. PTCs with BRAFV600E mutations are associated with ICAM-1 Overexpression; Figure S2. Tumor tissue morphology in ATC patients.; Figure S3. ICAM-1-overexpressing ATC cell lines are more proliferative.; Figure S4. ICAM-1 CAR T cell phenotype c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a9e310a181d4f64b0ec5200bddbe20
https://doi.org/10.1158/1078-0432.22463076.v1
https://doi.org/10.1158/1078-0432.22463076.v1
Autor:
Irene M. Min, Moonsoo M. Jin, Thomas J. Fahey, Rasa Zarnegar, Andrew B. Tassler, Theresa Scognamiglio, Paul J. Christos, Dessislava Stefanova, Heng Liang, Timothy M. Ullmann, Marjan Zaman, Enda Shevlin, Yanping Yang, Steve El Eshaky, Olivia R. Kalloo, Yogindra Vedvyas, Jaclyn E. McCloskey, Katherine D. Gray
Expression of ICAM1 and PD-L1 in anaplastic thyroid tumor cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6c3bf8bbbb48fc754c52a07636ea89
https://doi.org/10.1158/1078-0432.22476359
https://doi.org/10.1158/1078-0432.22476359
Autor:
Irene M. Min, Moonsoo M. Jin, Thomas J. Fahey, Rasa Zarnegar, Andrew B. Tassler, Theresa Scognamiglio, Paul J. Christos, Dessislava Stefanova, Heng Liang, Timothy M. Ullmann, Marjan Zaman, Enda Shevlin, Yanping Yang, Steve El Eshaky, Olivia R. Kalloo, Yogindra Vedvyas, Jaclyn E. McCloskey, Katherine D. Gray
PD1 inhibition enhances survival benefit of CAR T treatment in KHM-5M xenografts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c21a12ef8b3be9c3c8a123575945db
https://doi.org/10.1158/1078-0432.22476353
https://doi.org/10.1158/1078-0432.22476353
Autor:
Moonsoo M. Jin, Thomas J. Fahey, Rasa Zarnegar, Andrew B. Tassler, Katherine D. Gray, Suraj Panjwani, Spencer Park, Susan Park, Weibin Wang, Maureen D. Moore, Theresa Scognamiglio, Brian Wyrwas, Marjan Zaman, Yogindra Vedvyas, Enda Shevlin, Irene M. Min
Purpose: Poorly differentiated thyroid cancer and anaplastic thyroid cancer (ATC) are rare yet lethal malignancies with limited treatment options. Many malignant tumors, including papillary thyroid cancer (PTC) and ATC, are associated with increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3484f7a5c6bae0c0fda6c9d16275449e
https://doi.org/10.1158/1078-0432.c.6525303
https://doi.org/10.1158/1078-0432.c.6525303
Autor:
Jaclyn E. McCloskey, Katherine D. Gray, Moonsoo M. Jin, Marjan Zaman, Steve El Eshaky, Rasa Zarnegar, Andrew B. Tassler, Olivia R. Kalloo, Paul J. Christos, Heng Liang, Yogindra Vedvyas, Theresa Scognamiglio, Irene M. Min, Yanping Yang, Thomas J. Fahey, Dessislava Stefanova, Timothy M. Ullmann, Enda Shevlin
Publikováno v:
Clin Cancer Res
Purpose: Advanced thyroid cancers, including poorly differentiated and anaplastic thyroid cancer (ATC), are lethal malignancies with limited treatment options. The majority of patients with ATC have responded poorly to programmed death 1 (PD1) blocka
Autor:
Michael O’Dwyer, Enda Shevlin, Sarah Brophy, David Hermanson, Hallie Hintz, Neil Otto, Brianna Ettestad, Lucy Kirkham-McCarthy, Marjut Köylijärvi, David Hardwicke, Mary Reilly
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 22:S45-S46
Autor:
Weibin Wang, Susan Park, Irene M. Min, Enda Shevlin, Suraj Panjwani, Brian Wyrwas, Maureen D. Moore, Thomas J. Fahey, Katherine D. Gray, Theresa Scognamiglio, Spencer Park, Rasa Zarnegar, Yogindra Vedvyas, Andrew B. Tassler, Moonsoo M. Jin, Marjan Zaman
Publikováno v:
Clinical Cancer Research. 23:7569-7583
Purpose: Poorly differentiated thyroid cancer and anaplastic thyroid cancer (ATC) are rare yet lethal malignancies with limited treatment options. Many malignant tumors, including papillary thyroid cancer (PTC) and ATC, are associated with increased