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Autor:
Catherine Godson, Finian Martin, Enda Masterson, Gleb Grebnev, Karin Conde-Knape, Debra F. Higgins, Marco Prunotto, Sylvia Pomposiello, Leah M. Ewart, Sadhbh Tennant
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1863:3095-3104
Bone morphogenetic protein-7 (BMP-7) counteracts pro-fibrotic effects of TGFβ1 in cultured renal cells and protects from fibrosis in acute and chronic renal injury models. Using the unilateral ureteral obstruction (UUO) model of chronic renal fibros