Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Enchi, Liu"'
Autor:
Jonas Hannestad, Steven Smith, Andrew Lam, Janet Hurt, Nicole Harada, Richard Kim, Abhirup Das, Juliana Brunello, Gareth Whitaker, David Chalmers, Faria Senjoti, Wu Lin, James Coghill, Yogesh Bansal, Sharan Sidhu, Vanessa Zann, Enchi Liu
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 11, Pp n/a-n/a (2024)
Abstract TQS‐168, a first‐in‐class small‐molecule inducer of peroxisome proliferator‐activated receptor gamma coactivator 1‐alpha gene expression, is in development for the treatment of amyotrophic lateral sclerosis. A single‐ascending�
Externí odkaz:
https://doaj.org/article/bc0a9815794a41759b77b2f8b19ab4a2
Autor:
Zhengshi Yang, Jessica Z. K. Caldwell, Jeffrey L. Cummings, Aaron Ritter, Jefferson W. Kinney, Dietmar Cordes, The Alzheimer's Disease Neuroimaging Initiative (ADNI), Michael Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Enchi Liu, Tom Montine, Anthony Gamst, Ronald G. Thomas, Michael Donohue, Sarah Walter, Devon Gessert, Tamie Sather, Danielle Harvey, John Kornak, Anders Dale, Matthew Bernstein, Joel Felmlee, Nick Fox, Paul Thompson, Norbert Schuff, Gene Alexander, Charles DeCArli, Dan Bandy, Robert A. Koeppe, Norm Foster, Eric M. Reiman, Kewei Chen, Chet Mathis, Nigel J. Cairns, Lisa Taylor-Reinwald, J. Q. Trojanowki, Les Shaw, Virginia M.Y. Lee, Magdalena Korecka, Karen Crawford, Scott Neu, Tatiana M. Foroud, Steven Potkin, Li Shen, Zaven Khachaturian, Richard Frank, Peter J. Snyder, Susan Molchan, Jeffrey Kaye, Joseph Quinn, Betty Lind, Sara Dolen, Lon S. Schneider, Sonia Pawluczyk, Bryan M. Spann, James Brewer, Helen Vanderswag, Judith L. Heidebrink, Joanne L. Lord, Kris Johnson, Rachelle S. Doody, Javier Villanueva-Meyer, Munir Chowdhury, Yaakov Stern, Lawrence S. Honig, Karen L. Bell, John C. Morris, Beau Ances, Maria Carroll, Sue Leon, Mark A. Mintun, Stacy Schneider, Daniel Marson, Randall Griffith, David Clark, Hillel Grossman, Effie Mitsis, Aliza Romirowsky, Leyla deToledo-Morrell, Raj C. Shah, Ranjan Duara, Daniel Varon, Peggy Roberts, Marilyn Albert, Chiadi Onyike, Stephanie Kielb, Henry Rusinek, Mony J de Leon, Lidia Glodzik, P. Murali Doraiswamy, Jeffrey R. Petrella, Edward R. Coleman, Steven E. Arnold, Jason H. Karlawish, David Wolk, Charles D. Smith, Greg Jicha, Peter Hardy, Oscar L. Lopez, MaryAnn Oakley, Donna M. Simpson, Anton P. Porsteinsson, Bonnie S. Goldstein, Kim Martin, Kelly M. Makino, M. Saleem Ismail, Connie Brand, Ruth A. Mulnard, Gaby Thai, Catherine Mc-Adams-Ortiz, Ramon Diaz-Arrastia, Kristen Martin-Cook, Michael DeVous, Allan I. Levey, James J. Lah, Janet S. Cellar, Jeffrey M. Burns, Heather S Anderson, Russell H. Swerdlow, Liana Apostolova, Po H. Lu, George Bartzokis, Daniel H.S. Silverman, Neill R Graff-Radford, Francine Parfitt, Heather Johnson, Martin Farlow, Scott Herring, Ann M. Hake, Christopher H. van Dyck, Richard E. Carson, Martha G. MacAvoy, Howard Chertkow, Howard Bergman, Chris Hosein, Sandra Black, Bojana Stefanovic, Curtis Caldwell, Ging-Yuek Robin Hsiung, Howard Feldman, Michele Assaly, Andrew KertesZ, John Rogers, Dick Trost, Charles Bernick, Donna Munic, Diana Kerwin, Marek-Marsel Mesulam, Kristine Lipowski, Chuang-Kuo Wu, Nancy Johnson, Carl Sadowsky, Walter Martinez, Teresa Villena, Raymond Scott Turner, Kathleen Johnson, Brigid Reynolds, Reisa A. Sperling, Keith A. Johnson, Gad Marshall, Meghan Frey, Allyson Rosen, Jared Tinklenberg, Marwan Sabbagh, Christine Belden, Sandra Jacobson, Neil Kowall, Ronald Killiany, Andrew E. Budson, Alexander Norbash, Patricia Lynn Johnson, Thomas O. Obisesan, Saba Wolday, Salome K. Bwayo, Alan Lerner, Leon Hudson, Paula Ogrocki, Evan Fletcher, Owen Carmichael, John Olichney, Charles DeCarli, Smita Kittur, Michael Borrie, T-Y Lee, Rob Bartha, Sterling Johnson, Sanjay Asthana, Cynthia M. Carlsson, Steven G. Potkin, Adrian Preda, Dana Nguyen, Pierre Tariot, Adam Fleisher, Stephanie Reeder, Vernice Bates, Horacio Capote, Michelle Rainka, Barry A. Hendin, Douglas W. Scharre, Maria Kataki, Earl A. Zimmerman, Dzintra Celmins, Alice D. Brown, Godfrey D. Pearlson, Karen Blank, Karen Anderson, Robert B. Santulli, Eben S. Schwartz, Kaycee M. Sink, Jeff D. Williamson, Pradeep Garg, Franklin Watkins, Brian R. Ott, Henry Querfurth, Geoffrey Tremont, Stephen Salloway, Paul Malloy, Stephen Correia, Howard J. Rosen, Bruce L. Miller, Jacobo Mintzer, Crystal Flynn Longmire, Kenneth Spicer
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
PurposeTo assess the pathological aging effect on caudate functional connectivity among mild cognitive impairment (MCI) participants and examine whether and how sex and amyloid contribute to this process.Materials and MethodsTwo hundred and seventy-s
Externí odkaz:
https://doaj.org/article/92c86aca14574c809e6aa16de8a227c8
Autor:
Kirsi M. Kinnunen, Adam J. Schwarz, Emily C. Turner, Dorian Pustina, Emily C. Gantman, Mark F. Gordon, Richard Joules, Ariana P. Mullin, Rachael I. Scahill, Nellie Georgiou-Karistianis, The Huntington's Disease Regulatory Science Consortium (HD-RSC), Varun Aggarwal, Shazia Ali, Irina Antonijevic, Astri Arnesen, Nazem Atassi, Brian Beers, Beth Belluscio, Limor Ben Har, Angele Benard, Caroline Benn, Brian Bettencourt, Anu Bhattacharyya, Robi Blumenstein, Beth Borowsky, Bret Bostwick, Jackson Burton, Angelika Caputo, David Cooper, Brad Elmer, Rebecca Evans, Andrew Feigen, Terrence Fisher, Rebecca Fuller, Emily Gantman, Danielle Gartner, Michal Geva, Sandra Gonzalez, Adam Good, Mark Gordon, Jaya Goyal, Michael Hayden, Priyantha Herath, Steve Hersch, Jianying Hu, Elise Kayson, Eileen Koski, Bernhard Landwehrmeyer, Michelle Lax, Blair Leavitt, Dorothy Leong, Oren Levy, Enchi Liu, Jeff Long, Doug Macdonald, Jacqueline Major, Lahar Mehta, Tiago Mestre, Eric Miller, Christian Mueller, Catherine O'Riordan, Jennifer Panagoulias, Mike Panzara, Anne Pedata, Jennifer Petrillo-Billet, Dave Podskalny, Alisha Reader, Shelly Redman, Ralf Reilmann, Klaus Romero, Christopher Ross, Anne Rosser, Cristina Sampaio, Jan Samzelius, Scott Schobel, Adam Schwarz, Sudhir Sivakumaran, Jennie Socha, Glenn Stebbins, Julie Stout, Sarah Tabrizi, Emily Turner, Charles Venuto, Louise Vetter, Vissia Viglietta, Sarah Wahlstrom Helgren, Beth White, Ed Wild, George Yohrling, Maurice Zauderer
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Huntington's disease (HD) is an autosomal-dominant inherited neurodegenerative disorder that is caused by expansion of a CAG-repeat tract in the huntingtin gene and characterized by motor impairment, cognitive decline, and neuropsychiatric disturbanc
Externí odkaz:
https://doaj.org/article/ca6c677056d045fbbeff255dc7be3a75
Autor:
Nicholas P. France, Christopher Rubino, M. Courtney Safir, Mari Maurer, Tram Duong, Deepika Singamsetty, Khalid Abd‐Elaziz, Thomas Chou, Sethu Sankaranarayanan, Marieke Ettema, Rebecca Cosford, Peter Dogterom, Enchi Liu, Carrolee Barlow
Publikováno v:
Clinical Pharmacology in Drug Development.
Autor:
Tyler P. Molitor, Enchi Liu, Alyssa M. A. Toda, Kristin M. Andruska, Molly Murphy, Paul Wren, Jessica M. Bright, Holly J. Carlisle, Carrolee Barlow
Publikováno v:
Movement Disorders
Background A common genetic mutation that causes Parkinson's disease (PD) is the G2019S LRRK2 mutation. A precision medicine approach that selectively blocks only excess kinase activity of the mutant allele could yield a safe and effective treatment
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2012 (2012)
As the societal and economic burdens of Alzheimer's disease (AD) continue to mount, so does the need for therapies that slow the progression of the illness. Beta amyloid has long been recognized as the pathologic hallmark of AD, and the past decade h
Externí odkaz:
https://doaj.org/article/df2e3c0ed1a84423b76bda8dbe1a2b88
Autor:
Daniel Wang, Nzeera Ketter, Enchi Liu, Marwan N. Sabbagh, Ronald Black, Hany Rofael, H. Robert Brashear, Anton P. Porsteinsson, Nick C. Fox, Stephen Salloway, Stephen Carr, Reisa A. Sperling, Lawrence S. Honig
Publikováno v:
Journal of Alzheimer's Disease. 64:689-707
Background A 3-year extension of two Phase III parent studies of intravenous (IV) bapineuzumab in patients with mild-to-moderate Alzheimer's disease dementia (apolipoprotein (APOE) ɛ4 carriers and noncarriers) is summarized. Objectives The primary a
Publikováno v:
The Journal Of Prevention of Alzheimer's Disease. :1-9
Background: The Neuropsychological Test Battery (NTB) is a combination of widely used clinical neuropsychological tests measuring memory and executive function and was designed to overcome some of the limitations of the traditionally used Alzheimer�
Publikováno v:
Molecular Genetics and Metabolism. 129:S58-S59
Autor:
Frank Jessen, Kaj Blennow, Thomas J. Montine, David M. Holtzman, Clifford R. Jack, Jason Karlawish, Enchi Liu, Samantha Budd Haeberlein, Philip Scheltens, Christopher C. Rowe, Creighton H. Phelps, José Luis Molinuevo, Reisa A. Sperling, Katherine P. Rankin, David A. Bennett, Eric Siemers, William J. Jagust
Publikováno v:
Alzheimer's and Dementia, 15(1), 153-157. Elsevier
Jagust, W, Jack, C R, Bennett, D A, Blennow, K, Haeberlein, S B, Holtzman, D M, Jessen, F, Karlawish, J, Liu, E, Molinuevo, J L, Montine, T, Phelps, C, Rankin, K P, Rowe, C C, Scheltens, P, Siemers, E & Sperling, R 2019, ' “Alzheimer's disease” is neither “Alzheimer's clinical syndrome” nor “dementia” ', Alzheimer's and Dementia, vol. 15, no. 1, pp. 153-157 . https://doi.org/10.1016/j.jalz.2018.11.002
Jagust, W, Jack, C R, Bennett, D A, Blennow, K, Haeberlein, S B, Holtzman, D M, Jessen, F, Karlawish, J, Liu, E, Molinuevo, J L, Montine, T, Phelps, C, Rankin, K P, Rowe, C C, Scheltens, P, Siemers, E & Sperling, R 2019, ' “Alzheimer's disease” is neither “Alzheimer's clinical syndrome” nor “dementia” ', Alzheimer's and Dementia, vol. 15, no. 1, pp. 153-157 . https://doi.org/10.1016/j.jalz.2018.11.002
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0d2124aff025c5c9ece7e16aa91523
https://research.vumc.nl/en/publications/eca577d9-c3c3-41d4-932a-3c724e211480
https://research.vumc.nl/en/publications/eca577d9-c3c3-41d4-932a-3c724e211480