Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Encarnacion Martinez‐Salas"'
Autor:
Rosario Francisco-Velilla, Salvador Abellan, Juan Antonio Garcia-Martin, Juan Carlos Oliveros, Encarnacion Martinez-Salas
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 23-34 (2024)
GEMIN5 is a multifunctional protein involved in various aspects of RNA biology, including biogenesis of snRNPs and translation control. Reduced levels of GEMIN5 confer a differential translation to selective groups of mRNAs, and biallelic variants re
Externí odkaz:
https://doaj.org/article/f01c44795ddc421a916214668f534734
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract RNA-binding proteins are multifunctional molecules impacting on multiple steps of gene regulation. Gemin5 was initially identified as a member of the survival of motor neurons (SMN) complex. The protein is organized in structural and functio
Externí odkaz:
https://doaj.org/article/2c94ac9b10ac48dba28a83739b305069
Publikováno v:
FEBS Open Bio, Vol 12, Iss 6, Pp 1125-1141 (2022)
The genome of viruses classified as picornaviruses consists of a single monocistronic positive strand RNA. The coding capacity of these RNA viruses is rather limited, and thus, they rely on the cellular machinery for their viral replication cycle. Up
Externí odkaz:
https://doaj.org/article/45ea1592ed184ec3bf65b396dd44bcd9
Autor:
Rosario Francisco-Velilla, Azman Embarc-Buh, Salvador Abellan, Francisco del Caño-Ochoa, Santiago Ramón-Maiques, Encarnacion Martinez-Salas
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 6182-6191 (2022)
Gemin5 is a multifunctional RNA binding protein (RBP) organized in domains with a distinctive structural organization. The protein is a hub for several protein networks performing diverse RNA-dependent functions including regulation of translation, a
Externí odkaz:
https://doaj.org/article/11165f1e4822453bbbe1cfc1803de8a1
Autor:
Deepa S. Rajan, Sukhleen Kour, Tyler R. Fortuna, Margot A. Cousin, Sarah S. Barnett, Zhiyv Niu, Dusica Babovic-Vuksanovic, Eric W. Klee, Brian Kirmse, Micheil Innes, Siri Lynne Rydning, Kaja K. Selmer, Magnus Dehli Vigeland, Anne Kjersti Erichsen, Andrea H. Nemeth, Francisca Millan, Catherine DeVile, Katherine Fawcett, Adrien Legendre, David Sims, Ricardo Parolin Schnekenberg, Lydie Burglen, Sandra Mercier, Somayeh Bakhtiari, Rosario Francisco-Velilla, Azman Embarc-Buh, Encarnacion Martinez-Salas, Kristen Wigby, Jerica Lenberg, Jennifer R. Friedman, Michael C. Kruer, Udai Bhan Pandey
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The hereditary ataxias are a heterogenous group of disorders with an increasing number of causative genes being described. Due to the clinical and genetic heterogeneity seen in these conditions, the majority of such individuals endure a diagnostic od
Externí odkaz:
https://doaj.org/article/5d4040678c7b47c1897c45d67b96d069
Publikováno v:
Viruses, Vol 13, Iss 6, p 952 (2021)
Viral RNAs contain the information needed to synthesize their own proteins, to replicate, and to spread to susceptible cells. However, due to their reduced coding capacity RNA viruses rely on host cells to complete their multiplication cycle. This is
Externí odkaz:
https://doaj.org/article/a8203b8c113d4b3c9d33348987069371
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 3868 (2020)
RNA-binding proteins (RBPs) play a pivotal role in the lifespan of RNAs. The disfunction of RBPs is frequently the cause of cell disorders which are incompatible with life. Furthermore, the ordered assembly of RBPs and RNAs in ribonucleoprotein (RNP)
Externí odkaz:
https://doaj.org/article/499cfd1675b144fe8b2a8d0218aca4af
Publikováno v:
Open Biology, Vol 8, Iss 11 (2018)
Beyond the general cap-dependent translation initiation, eukaryotic organisms use alternative mechanisms to initiate protein synthesis. Internal ribosome entry site (IRES) elements are cis-acting RNA regions that promote internal initiation of transl
Externí odkaz:
https://doaj.org/article/8880b07eeb8f446d80139b274bd3018d
Autor:
Encarnacion Martinez-Salas, Rosario Francisco-Velilla, Javier Fernandez-Chamorro, Azman M. Embarek
Publikováno v:
Frontiers in Microbiology, Vol 8 (2018)
Internal ribosome entry site (IRES) elements are cis-acting RNA regions that promote internal initiation of protein synthesis using cap-independent mechanisms. However, distinct types of IRES elements present in the genome of various RNA viruses perf
Externí odkaz:
https://doaj.org/article/49d7cce5512b40fb859b083dd214ee1a
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41382 (2012)
Translation initiation of picornavirus RNA is driven by an internal ribosome entry site (IRES) element located upstream of the initiator codon. RNA structure organization as well as RNA-protein interaction plays a fundamental role in internal initiat
Externí odkaz:
https://doaj.org/article/bebf4532b920428498871523ed96c300