Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Enantioselective pharmacokinetics"'
Akademický článek
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Akademický článek
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Publikováno v:
European journal of clinical pharmacology. 76(2)
Purpose The primary aim of this study was to explore the potential of alternative sampling matrices for methylphenidate by assessing the correlations between dl-threo-methylphenidate and dl-threo-ritalinic acid concentrations in exhaled breath and or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e8e71b512d49b16f01e0a30bbc188c
https://pubmed.ncbi.nlm.nih.gov/31786618
https://pubmed.ncbi.nlm.nih.gov/31786618
Publikováno v:
Journal of psychopharmacology (Oxford, England). 32(10)
Background: Ketamine has been shown to produce a rapid and potent antidepressant response in patients with treatment-resistant depression. Currently ketamine is most commonly administered as a 40-minute intravenous infusion, though it is unknown whet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d688f98f992a57a088b13529218004
https://pubmed.ncbi.nlm.nih.gov/29895202
https://pubmed.ncbi.nlm.nih.gov/29895202
Autor:
Martin Josefsson, Fredrik C. Kugelberg, Henrik Gréen, Pernilla Haage, Robert Kronstrand, Ron H.N. van Schaik, Simona Calistri
Publikováno v:
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives, 6(4):UNSP e00419. Wiley-Blackwell Publishing Ltd
Pharmacology Research & Perspectives, 6(4):UNSP e00419. Wiley-Blackwell Publishing Ltd
Tramadol is a complex drug, being metabolized by polymorphic enzymes and administered as a racemate with the (+)‐ and (−)‐enantiomers of the parent compound and metabolites showing different pharmacological effects. The study aimed to simultane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea7ebe538ce04dff2b728f11bd1b719
https://pure.eur.nl/en/publications/07a92aa1-6191-4157-92f8-d20707331dad
https://pure.eur.nl/en/publications/07a92aa1-6191-4157-92f8-d20707331dad
Akademický článek
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Publikováno v:
Chirality. 27:53-57
The enantioselective pharmacokinetics of TJ0711 hydrochloride were studied in rats given different doses of rac-TJ0711 hydrochloride via intravenous and oral routes. R- and S-TJ0711 hydrochloride were both rapidly absorbed, and the average AUC0-∞ o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad3a13ac1a37030509beb45830b7f750
https://doi.org/10.1002/chir.22387
https://doi.org/10.1002/chir.22387
Autor:
Maria Paula Marques Pereira, Jorge Manuel Vieira Capela, José Salvador Lepera, Vera Lucia Lanchote, Juciane Lauren Cavalcanti Cardoso
Publikováno v:
Chirality. 25:206-210
Departamento de Analises Clinicas, Toxicologicas e Bromatologicas Faculdade de Ciencias Farmaceuticas de Ribeirao Preto Universidade de Sao Paulo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91bdb912429cc772210257d10111583a
https://doi.org/10.1002/chir.22136
https://doi.org/10.1002/chir.22136
Autor:
Facundo Martín Bertera, Diego A. Chiappetta, Fabian Buontempo, Christian Höcht, Marcos A. Mayer, Carla Di Verniero, Ariel H. Polizio, Carlos A. Taira
Publikováno v:
Xenobiotica. 42:206-219
The cardiovascular effects and mechanism of antihypertensive response of carvedilol were assessed in fructose fed rats using pharmacokinetic–pharmacodynamic (PK-PD) modelling. Male Sprague Dowley rats were randomly divided into two groups: control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa88692d580ec68abd4e8f9e37bf2ed
https://doi.org/10.3109/00498254.2011.604746
https://doi.org/10.3109/00498254.2011.604746
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 34:153-159
Fosse, T. K., Horsberg, T. E., Haga, H. A., Hormazabal, V., Ranheim, B. Enantioselective pharmacokinetics of ketoprofen in piglets: the significance of neonatal age. J. vet. Pharmacol. Therap. 34, 153‐159. Following intravenous dose of 6 mg ⁄kg r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::232e687cf2a0221ff56812d978c9c51c
https://doi.org/10.1111/j.1365-2885.2010.01205.x
https://doi.org/10.1111/j.1365-2885.2010.01205.x