Zobrazeno 1 - 10
of 550
pro vyhledávání: '"Ena Wang"'
Autor:
Muna Al Hashmi, Konduru S. Sastry, Lee Silcock, Lotfi Chouchane, Valentina Mattei, Nicola James, Rebecca Mathew, Davide Bedognetti, Valeria De Giorgi, Daniela Murtas, Wei Liu, Aouatef Chouchane, Ramzi Temanni, Barbara Seliger, Ena Wang, Francesco M. Marincola, Sara Tomei
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-9 (2020)
Abstract Background Most mutations in melanoma affect one critical amino acid on BRAF gene, resulting in the V600E substitution. Patient management is often based on the use of specific inhibitors targeting this mutation. Methods DNA and RNA mutation
Externí odkaz:
https://doaj.org/article/76b0fbde5d5541b99ead96b5816d2060
Autor:
Lee Silcock, Hakeem Almabrazi, Younes Mokrab, Puthen Jithesh, Muna Al-Hashmi, Nicola James, Rebecca Mathew, Valentina Mattei, Davide Bedognetti, Francesca Lessi, Ramzi Temanni, Barbara Seliger, Rashid Al-Ali, Francesco M. Marincola, Ena Wang, Sara Tomei
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-7 (2019)
Abstract Background Monoallelic expression (MAE) is a frequent genomic phenomenon in normal tissues, however its role in cancer is yet to be fully understood. MAE is defined as the expression of a gene that is restricted to one allele in the presence
Externí odkaz:
https://doaj.org/article/fd11d94296a64e7f83edce668d7c986b
Autor:
Zhenwu Luo, Min Li, Yongxia Wu, Zhefeng Meng, Lisa Martin, Lumin Zhang, Elizabeth Ogunrinde, Zejun Zhou, Shenghui Qin, Zhuang Wan, Maria Anna Julia Westerink, Stephanie Warth, Hui Liu, Ping Jin, David Stroncek, Quan-Zhen Li, Ena Wang, Xueling Wu, Sonya L. Heath, Zihai Li, Alexander V. Alekseyenko, Wei Jiang
Publikováno v:
Microbiome, Vol 7, Iss 1, Pp 1-16 (2019)
Abstract Background Increased autoreactive antibodies have been reported in HIV disease; however, the mechanism accounting for autoantibody induction in HIV remains unknown. Results Herein, we show that seasonal influenza vaccination induces autoanti
Externí odkaz:
https://doaj.org/article/449377d5ac14496982dff9d66f66a81d
Autor:
Lisa H. Butterfield, Mary L. Disis, Bernard A. Fox, David R. Kaufman, Samir N. Khleif, Ena Wang, on behalf of the Society for Immunotherapy of Cancer Immuno-Oncology Biomarkers: State of the Art workshop speakers
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-13 (2018)
Abstract Identification of biomarkers in cancer immunotherapy that predict therapeutic response and/or limit adverse events are a critical need in the field. To address recent progress and hurdles around cancer biomarker development and utilization,
Externí odkaz:
https://doaj.org/article/74b8eea006a346f5a4830396f0b56bb7
Autor:
Sara Deola, Bella S. Guerrouahen, Heba Sidahmed, Anjud Al-Mohannadi, Muhammad Elnaggar, Ramaz Elsadig, Essam M. Abdelalim, Goran Petrovski, Massimo Gadina, Adrian Thrasher, Winfried S. Wels, Stephen P. Hunger, Ena Wang, Francesco M. Marincola, ATH Consortium, Cristina Maccalli, Chiara Cugno
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-15 (2018)
Abstract New technologies and therapies designed to facilitate development of personalized treatments are rapidly emerging in the field of biomedicine. Strikingly, the goal of personalized medicine refined the concept of therapy by developing cell-ba
Externí odkaz:
https://doaj.org/article/224e584b3e3a4cd5860bba423421ef7d
Autor:
Ena Wang, Alessandra Cesano, Beatrix Kotlan, Mohan Karkada, Nicholas Tschernia, Aung Naing, Bruno Gomes, Anne Monette, Vésteinn Thórsson, Sergio Rutella, Vaios Karanikas, Michael A Cannarile, Justin Guinney, Giuseppe V Masucci, Els Meeusen, Daniel K Wells, Timothy L Wyant
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
The development of strongly predictive validated biomarkers is essential for the field of immuno-oncology (IO) to advance. The highly complex, multifactorial data sets required to develop these biomarkers necessitate effective, responsible data-shari
Externí odkaz:
https://doaj.org/article/093f0e8ec32a4d008042f3b582974250
Autor:
Paolo A. Ascierto, Igor Puzanov, Sanjiv S. Agarwala, Carlo Bifulco, Gerardo Botti, Corrado Caracò, Gennaro Ciliberto, Michael A. Davies, Reinhard Dummer, Soldano Ferrone, Thomas F. Gajewski, Claus Garbe, Jason J. Luke, Francesco M. Marincola, Giuseppe Masucci, Janice M. Mehnert, Nicola Mozzillo, Giuseppe Palmieri, Michael A. Postow, Stephen P. Schoenberger, Ena Wang, Magdalena Thurin
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-13 (2018)
Abstract Metastatic melanoma represents a challenging clinical situation and, until relatively recently, there was an absence of effective treatment options. However, in 2011, the advanced melanoma treatment landscape was revolutionised with the appr
Externí odkaz:
https://doaj.org/article/2d1e71fc5d4043f99a44acdb17e481d6
Autor:
Giuseppe V. Masucci, Alessandra Cesano, Alexander Eggermont, Bernard A. Fox, Ena Wang, Francesco M. Marincola, Gennaro Ciliberto, Kevin Dobbin, Igor Puzanov, Janis Taube, Jennifer Wargo, Lisa H. Butterfield, Lisa Villabona, Magdalena Thurin, Michael A. Postow, Paul M. Sondel, Sandra Demaria, Sanjiv Agarwala, Paolo A. Ascierto
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-10 (2017)
Abstract Immunotherapies have emerged as one of the most promising approaches to treat patients with cancer. Recently, the entire medical oncology field has been revolutionized by the introduction of immune checkpoints inhibitors. Despite success in
Externí odkaz:
https://doaj.org/article/c05028c2cdee4748b3c4d55fdebe136f
Autor:
Sara Tomei, Andrea Volontè, Shilpa Ravindran, Stefania Mazzoleni, Ena Wang, Rossella Galli, Cristina Maccalli
Publikováno v:
Journal of Personalized Medicine, Vol 11, Iss 4, p 264 (2021)
Glioblastoma (GBM) represents the most common and aggressive tumor of the brain. Despite the fact that several studies have recently addressed the molecular mechanisms underlying the disease, its etiology and pathogenesis are still poorly understood.
Externí odkaz:
https://doaj.org/article/1cc66a2affb4433baa52227bb3bf4946
Autor:
Santosh K. Yadav, Rakesh K. Gupta, Ravindra K. Garg, Vimala Venkatesh, Pradeep K. Gupta, Alok K. Singh, Sheema Hashem, Asma Al-Sulaiti, Deepak Kaura, Ena Wang, Francesco M. Marincola, Mohammad Haris
Publikováno v:
NeuroImage: Clinical, Vol 14, Iss C, Pp 316-322 (2017)
Pediatric HIV patients often suffer with neurodevelopmental delay and subsequently cognitive impairment. While tissue injury in cortical and subcortical regions in the brain of adult HIV patients has been well reported there is sparse knowledge about
Externí odkaz:
https://doaj.org/article/032621fc9cb04e1d9466ef38f6e9f67d