Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ena Španić"'
Autor:
Ena Španić Popovački, Mirjana Babić Leko, Lea Langer Horvat, Klara Brgić, Željka Vogrinc, Marina Boban, Nataša Klepac, Fran Borovečki, Goran Šimić
Publikováno v:
Neurology International, Vol 15, Iss 3, Pp 842-856 (2023)
Background: Individuals with specific TREM2 gene variants that encode for a Triggering Receptor Expressed on Myeloid cells 2 have a higher prevalence of Alzheimer’s disease (AD). By interacting with amyloid and apolipoproteins, the TREM2 receptor r
Externí odkaz:
https://doaj.org/article/524abe23403f4537a0329e68888209fd
Autor:
Ena Španić Popovački, Dora Vogrinc, Heidi R. Fuller, Lea Langer Horvat, Davor Mayer, Janja Kopić, Klara Pintarić, Mirjana Babić Leko, Mihaela Pravica, Željka Krsnik, Darko Marčinko, Marina Šagud, Patrick R. Hof, Mihovil Mladinov, Goran Šimić
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 302 (2024)
Schizophrenia is a complex mental condition, with key symptoms marked for diagnosis including delusions, hallucinations, disorganized thinking, reduced emotional expression, and social dysfunction. In the context of major developmental hypotheses of
Externí odkaz:
https://doaj.org/article/e34270c8e3fc4196bdbbbdb3795de0d9
Autor:
Mirjana Babić Leko, Lea Langer Horvat, Ena Španić Popovački, Klara Zubčić, Patrick R. Hof, Goran Šimić
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1161 (2023)
The role of metals in the pathogenesis of Alzheimer’s disease (AD) is still debated. Although previous research has linked changes in essential metal homeostasis and exposure to environmental heavy metals to the pathogenesis of AD, more research is
Externí odkaz:
https://doaj.org/article/c349bfc03adf4043b53fca1f50e14898
Autor:
Lea Langer Horvat, Ena Španić Popovački, Mirjana Babić Leko, Klara Zubčić, Luka Horvat, Maja Mustapić, Patrick R. Hof, Goran Šimić
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1004 (2023)
The tauopathy of Alzheimer’s disease (AD) is first observed in the brainstem and entorhinal cortex, spreading trans-synaptically along specific pathways to other brain regions with recognizable patterns. Tau propagation occurs retrogradely and ante
Externí odkaz:
https://doaj.org/article/ae5386b7891540c59cddaabf9ba0eb68
Autor:
Mirjana Babić Leko, Matea Nikolac Perković, Ena Španić, Dubravka Švob Štrac, Nikolina Pleić, Željka Vogrinc, Ivana Gunjača, Dora Bežovan, Gordana Nedić Erjavec, Nataša Klepac, Fran Borovečki, Tatijana Zemunik, Nela Pivac, Patrick R. Hof, Goran Šimić
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3118 (2022)
A decrease in serotonergic transmission throughout the brain is among the earliest pathological changes in Alzheimer’s disease (AD). Serotonergic receptors are also affected in AD. Polymorphisms in genes of serotonin (5HT) receptors have been mostl
Externí odkaz:
https://doaj.org/article/313b3714eecd4961a99c3c81f56df4f5
Autor:
Mirjana Babić Leko, Matej Mihelčić, Jasna Jurasović, Matea Nikolac Perković, Ena Španić, Ankica Sekovanić, Tatjana Orct, Klara Zubčić, Lea Langer Horvat, Nikolina Pleić, Spomenka Kiđemet-Piskač, Željka Vogrinc, Nela Pivac, Andrea Diana, Fran Borovečki, Patrick R. Hof, Goran Šimić
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 467 (2022)
Various metals have been associated with the pathogenesis of Alzheimer’s disease (AD), principally heavy metals that are environmental pollutants (such as As, Cd, Hg, and Pb) and essential metals whose homeostasis is disturbed in AD (such as Cu, Fe
Externí odkaz:
https://doaj.org/article/75bd3cfccd934e9f818cb3dc968eeccd
Publikováno v:
Cells, Vol 11, Iss 14, p 2223 (2022)
Neuroinflammation is one of the core pathological features of Alzheimer’s disease (AD) as both amyloid β (Aβ) and tau monomers and oligomers can trigger the long-term pro-inflammatory phenotype of microglial cells with consequent overactivation o
Externí odkaz:
https://doaj.org/article/6a21f330ff254eebbe479a5fff049675
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Uncontrolled immune response in the brain contributes to the progression of all neurodegenerative disease, including Alzheimer’s disease (AD). Recent investigations have documented the prion-like features of tau protein and the involvement of micro
Externí odkaz:
https://doaj.org/article/77298e218016416d92ddfb82402f5140
Autor:
Goran Šimić, Mladenka Tkalčić, Vana Vukić, Damir Mulc, Ena Španić, Marina Šagud, Francisco E. Olucha-Bordonau, Mario Vukšić, Patrick R. Hof
Publikováno v:
Biomolecules, Vol 11, Iss 6, p 823 (2021)
Emotions arise from activations of specialized neuronal populations in several parts of the cerebral cortex, notably the anterior cingulate, insula, ventromedial prefrontal, and subcortical structures, such as the amygdala, ventral striatum, putamen,
Externí odkaz:
https://doaj.org/article/81e589de2877415b8202f08021225d3d
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