Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Ena/Vasp homology proteins"'
Publikováno v:
The Journal of Cell Biology
CRMP proteins regulate the cytoskeleton, but the underlying mechanisms are poorly understood. Yu-Kemp et al. show that CRMP-1 helps Ena/VASP proteins elongate actin filaments to assemble actin networks that are necessary for the integrity of epitheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3eed6d2c677a6a6f6cdd018e82badb
http://europepmc.org/articles/PMC5551698
http://europepmc.org/articles/PMC5551698
Publikováno v:
Microbiology. 161:2149-2160
Shigella spp. are intracellular bacterial pathogens that cause diarrhoeal disease in humans. Shigella utilize the host actin cytoskeleton to enter cells, move through the cytoplasm of cells and pass into adjacent cells. Ena/VASP family proteins are h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580a0d613e03dfefe0a8bc9b00429428
https://doi.org/10.1099/mic.0.000173
https://doi.org/10.1099/mic.0.000173
Autor:
Sally Martin, Peter Josh, Andreas Papadopulos, Rachel S. Gormal, Frederic A. Meunier, Vanesa M. Tomatis, Vanessa Lanoue
Publikováno v:
Molecular and cellular neurosciences. 84
In neurosecretory cells, myosin VI associated with secretory granules (SGs) mediates their activity-dependent recruitment to the cortical actin network and is necessary to sustain exocytosis. The mechanism by which myosin VI interacts with SGs is unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cebd941df0aef1f034904ba83bc163d9
https://pubmed.ncbi.nlm.nih.gov/28784263
https://pubmed.ncbi.nlm.nih.gov/28784263
Autor:
Irina Kuzina, Stephen Wincovitch, Edward Giniger, Ramakrishnan Kannan, Stephanie H. Nowotarski
Publikováno v:
Molecular Biology of the Cell
The Abl tyrosine kinase signaling pathway, including its key effector, the actin regulatory protein Enabled, controls the fragmentation state and subcellular localization of the Golgi compartment in Drosophila photoreceptor neurons via Abl/Enabled-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d52416bad9655299fc69574f81e83f
https://doi.org/10.1091/mbc.e14-02-0729
https://doi.org/10.1091/mbc.e14-02-0729
Publikováno v:
Development (Cambridge, England)
MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression that play important roles in nervous system development and physiology. However, our understanding of the strategies by which miRNAs control synapse development is limited. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2011729b78809409eda95e0be58b309
https://doi.org/10.1242/dev.105791
https://doi.org/10.1242/dev.105791
Autor:
Timothy C. Elston, Denis Tsygankov, Mark Peifer, David R. Kovar, Vinal V. Lakhani, Kate Comber, Stephanie H. Nowotarski, Will J Wood, Colleen G. Bilancia, Jennifer A. Sees, Iwan Robert Evans, Jonathan D. Winkelman
Publikováno v:
Developmental Cell
Summary Actin regulators facilitate cell migration by controlling cell protrusion architecture and dynamics. As the behavior of individual actin regulators becomes clear, we must address why cells require multiple regulators with similar functions an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbeec7b680217dd883272bf1de30843b
http://europepmc.org/articles/PMC3992947
http://europepmc.org/articles/PMC3992947
Publikováno v:
Molecular Biology of the Cell
Tight regulation of actin remodeling is essential for development, and misregulation results in disease. Cytoskeletal dynamics are regulated by prostaglandins (PGs)—lipid signals. PGs temporally regulate actin remodeling during Drosophila oogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eaed78aca0288d1b084fc7dd9febddc
http://europepmc.org/articles/PMC3907279
http://europepmc.org/articles/PMC3907279
Publikováno v:
Journal of Biological Chemistry. 288:24382-24393
Enabled/Vasodilator-stimulated phosphoprotein (Ena/VASP) protein family members link actin dynamics and cellular signaling pathways. VASP localizes to regions of dynamic actin reorganization such as the focal adhesion contacts, the leading edge or fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4656f6164a279d65a1b1f7df9e061b3c
https://doi.org/10.1074/jbc.m113.474676
https://doi.org/10.1074/jbc.m113.474676
Autor:
Moritz Winterhoff, Christophe Ampe, Giorgio Scita, David J. Kast, Andrea Disanza, Hans-Michael Müller, Paola Marighetti, Francesca Milanesi, Joern Linkner, Salvatore Cortellino, Jan Faix, Roberto Dominguez, Dmitry S. Ushakov, Davy Waterschoot, Marie-France Carlier, Sara Bisi, Andrea Palamidessi, Walter Nickel, Guillaume Romet-Lemonne
Publikováno v:
The EMBO Journal; Vol 32
The EMBO Journal
The EMBO Journal
Filopodia explore the environment, sensing soluble and mechanical cues during directional motility and tissue morphogenesis. How filopodia are initiated and spatially restricted to specific sites on the plasma membrane is still unclear. Here, we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0017c1e4fd489c424fb6e5282345f91a
Autor:
John H. Hartwig, Laura M. Selfors, R. Dyche Mullins, Frank B. Gertler, Lara J. Petrak, Joan S. Brugge, Scott D. Hansen, Michele M. Hickey, Lisa L. Gallegos, James Lim, Ghassan Mouneimne, Kaylene J. Simpson
Publikováno v:
Cancer Cell. 22:615-630
SummaryDynamic actin cytoskeletal reorganization is integral to cell motility. Profilins are well-characterized regulators of actin polymerization; however, functional differences among coexpressed profilin isoforms are not well defined. Here, we dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa6efa41559c2e38b2f085b805cb4d9
https://doi.org/10.1016/j.ccr.2012.09.027
https://doi.org/10.1016/j.ccr.2012.09.027