Zobrazeno 1 - 10
of 60
pro vyhledávání: '"En-Sheng Ji"'
Autor:
Yu Chen, Meng Xu, Xiao-Mei Liu, Jian-Xin Wang, Meng-Fan Sun, Ji-Xian Song, Peng Guan, En-Sheng Ji, Na Wang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116653- (2024)
Huangqi Guizhi Wuwu Decoction (HQGZWWD) has shown promising potential in treating various cardiovascular diseases. This study aimed to elucidate the molecular basis and therapeutic role of HQGZWWD in the treatment of doxorubicin (DOX)-induced myocard
Externí odkaz:
https://doaj.org/article/7ea8a24890f448ad80e279c8e1375c47
Publikováno v:
Pharmaceutical Biology, Vol 60, Iss 1, Pp 609-620 (2022)
Context Obstructive sleep apnoea (OSA) causes chronic intermittent hypoxia (CIH), which results in mitochondrial dysfunction and generates reactive oxygen species (ROS) in the heart. Excessive free iron could accelerate oxidative damage, which may be
Externí odkaz:
https://doaj.org/article/13c1826ec4f740e6ab39cc16dae95a37
Autor:
Lu-Yun Qin, Peng Guan, Jian-Xin Wang, Yu Chen, Ya-Shuo Zhao, Sheng-Chang Yang, Ya-Jing Guo, Na Wang, En-Sheng Ji
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Adriamycin (ADR) has been utilized to treat cancer for several decades. However, ADR-induced renal injury is one of the most common side effects accompanying ADR therapy. In the present study, we revealed that astragaloside IV (ASIV) was beneficial f
Externí odkaz:
https://doaj.org/article/154bb9ef36824b14be17f0b73a05701a
Autor:
Ai-Ying Li, Jing-Jing Wang, Sheng-Chang Yang, Ya-Shuo Zhao, Jie-Ru Li, Yu Liu, Jia-Huan Sun, Li-Ping An, Peng Guan, En-Sheng Ji
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 110, Iss , Pp 733-741 (2019)
Gentianella acuta (Michx.) Hulten (G. acuta) has been widely used in Mongolian medicines for the treatment of cardiovascular diseases in Ewenki and Oroqen, Inner Mongolia autonomous region, China. The aim of this study was to investigate the effects
Externí odkaz:
https://doaj.org/article/f6610edb8111443595ab1aa63a205c56
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Astragaloside IV (ASIV) is the main active component of Astragalus, and can ameliorate cardiomyocyte hypertrophy, apoptosis and fibrosis. In this experiment, we studied how ASIV reduces the cardiotoxicity caused by adriamycin and protects the heart.
Externí odkaz:
https://doaj.org/article/e008cd6af601493f8ef7b01b0465125d
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195604 (2018)
Endothelial dysfunction is one of the main pathological changes in Obstructive sleep apnoea (OSA). The Rho kinase (ROCK) pathway is associated with endothelial dysfunction. However, the interaction between ROCK and nuclear factor of activated T cells
Externí odkaz:
https://doaj.org/article/657d91a900c348b0b316563d3e39b022
Autor:
Peng Guan, Zhi-Min Sun, Li-Fei Luo, Ya-Shuo Zhao, Sheng-Chang Yang, Fu-Yang Yu, Na Wang, En-Sheng Ji
Publikováno v:
Molecules, Vol 24, Iss 6, p 1184 (2019)
Iron-induced oxidative stress has been found to be a central player in the pathogenesis of kidney injury. Recent studies have indicated H2 can be used as a novel antioxidant to protect cells. The present study was designed to investigate the protecti
Externí odkaz:
https://doaj.org/article/fd4741bd92344001a602b4876def5cba
Autor:
Zhuo Wang, Ai-Ying Li, Qiu-Hong Guo, Jian-Ping Zhang, Qi An, Ya-jing Guo, Li Chu, J Woodrow Weiss, En-Sheng Ji
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58078 (2013)
Obstructive sleep apnoea (OSA) is a risk factor for cardiovascular disorders and in some cases is complication of pulmonary hypertension. We simulated OSA by exposing rats to cyclic intermittent hypoxia (CIH) to investigate its effect on pulmonary va
Externí odkaz:
https://doaj.org/article/30f7e66007374ba698f75ad75506aef7
Autor:
Xin-Yue Yang, Lina Geng, Ronghui Li, Ji-Xian Song, Cui-Ling Jia, Ji-Ren An, Meng-Fan Sun, Shan Xu, Ya-Jing Guo, Yashuo Zhao, En-Sheng Ji
Publikováno v:
International Journal of Nanomedicine. 18:843-859
Xin-Yue Yang,1,* Lina Geng,2,* Ronghui Li,2 Ji-Xian Song,1 Cui-Ling Jia,1 Ji-Ren An,1,3 Meng-Fan Sun,1 Shan Xu,1 Ya-Jing Guo,1 Yashuo Zhao,1 En-Sheng Ji1 1Hebei Technology Innovation Center of TCM Combined Hydrogen Medicine, Hebei University
Publikováno v:
Molecular and Cellular Biochemistry. 476:2603-2611
Astragaloside IV (AsIV), an active ingredient isolated from traditional Chinese medicine astragalus membranaceus, is beneficial to cardiovascular health. This study aimed to characterize the functional role of AsIV against adriamycin (ADR)-induced ca