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Monocarboxylate transporter 1 and monocarboxylate transporter 4 in cancer-endothelial co-culturing microenvironments promote proliferation, migration, and invasion of renal cancer cells

Autor: Chen Guo, Tao Huang, Qing-Hai Wang, Hong Li, Aashish Khanal, En-Hao Kang, Wei Zhang, Hai-Tao Niu, Zhen Dong, Yan-Wei Cao

Publikováno v: Cancer Cell International, Vol 19, Iss 1, Pp 1-11 (2019)

Abstract Background The Warburg effect demonstrates the importance of glycolysis in the development of primary and metastatic cancers. We aimed to explore the role of monocarboxylate transporter 1 (MCT1) and MCT4, two essential transporters of lactat

Externí odkaz: https://doaj.org/article/527f850b116046d0bd14242f13955c02

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Monocarboxylate transporters MCT1 and MCT4 are independent prognostic biomarkers for the survival of patients with clear cell renal cell carcinoma and those receiving therapy targeting angiogenesis

Autor: En-Hao Kang, Lei Guo, Yong Liu, Wei Zhang, Zhen Dong, Yanwei Cao, Yonghua Wang, Haitao Niu

Publikováno v: Urologic oncology. 36(6)

Background Prognostic biomarkers for patients with clear cell renal cell carcinoma (ccRCC), particularly those receiving therapy targeting angiogenesis, are not well established. In this study, we examined the correlations of monocarboxylate transpor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d291c3fd3a64679ba762aebd9f6f8e10
https://pubmed.ncbi.nlm.nih.gov/29657088

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