Zobrazeno 1 - 10
of 66
pro vyhledávání: '"En-Chi Hsu"'
Autor:
Shiqin Liu, Sarah J. Hawley, Christian A. Kunder, En-Chi Hsu, Michelle Shen, Lennart Westphalen, Heidi Auman, Lisa F. Newcomb, Daniel W. Lin, Peter S. Nelson, Ziding Feng, Maria S. Tretiakova, Lawrence D. True, Funda Vakar-Lopez, Peter R. Carroll, Jeffry Simko, Martin E. Gleave, Dean A. Troyer, Jesse K. McKenney, James D. Brooks, Michael A. Liss, Tanya Stoyanova
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Distinguishing indolent from clinically significant localized prostate cancer is a major clinical challenge and influences clinical decision-making between treatment and active surveillance. The development of novel predictive biomarkers wil
Externí odkaz:
https://doaj.org/article/71e4a4bb78964d77b74c7c002f70c24d
Autor:
En‐Chi Hsu, Kuan‐Li Wu, Ying‐Ming Tsai, Mei‐Hsuan Lee, Ming‐Ju Tsai, Chia‐Yu Kuo, Yu‐Chuan Liu, Fu‐Wen Liang, Chih‐Jen Yang, Jen‐Yu Hung
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 38, Iss 10, Pp 1001-1011 (2022)
Abstract Lung squamous cell carcinoma (LUSC) represents a minor proportion of nonsmall cell lung cancer (NSCLC) harboring a poor prognosis. Herein, retrospective medical record research was performed to investigate real‐world treatment patterns and
Externí odkaz:
https://doaj.org/article/db029e59fd1b48689719a60fac4223f8
Autor:
Merve Aslan, En-Chi Hsu, Fernando J. Garcia-Marques, Abel Bermudez, Shiqin Liu, Michelle Shen, Meredith West, Chiyuan Amy Zhang, Meghan A. Rice, James D. Brooks, Robert West, Sharon J. Pitteri, Balázs Győrffy, Tanya Stoyanova
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract Breast cancer remains the second most lethal cancer among women in the United States and triple-negative breast cancer is the most aggressive subtype with limited treatment options. Trop2, a cell membrane glycoprotein, is overexpressed in al
Externí odkaz:
https://doaj.org/article/2e9619dd7502478fa340f2896da35a31
Autor:
En-Chi Hsu, Michelle Shen, Merve Aslan, Shiqin Liu, Manoj Kumar, Fernando Garcia-Marques, Holly M. Nguyen, Rosalie Nolley, Sharon J. Pitteri, Eva Corey, James D. Brooks, Tanya Stoyanova
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Neuroendocrine prostate cancer (NEPC) is a lethal subtype of prostate cancer that rarely develops de novo in primary tumors and is commonly acquired during the development of treatment resistance. NEPC is characterized by gain of neuroendocr
Externí odkaz:
https://doaj.org/article/0691e54f4cb8403ba947ac009a53d0a8
Autor:
Shiqin Liu, Fernando Garcia-Marques, Chiyuan Amy Zhang, Jordan John Lee, Rosalie Nolley, Michelle Shen, En-Chi Hsu, Merve Aslan, Kashyap Koul, Sharon J. Pitteri, James D. Brooks, Tanya Stoyanova
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Prostate cancer remains the most common non-cutaneous malignancy among men in the United States. To discover potential serum-based biomarkers for high-risk prostate cancer, we performed a high-multiplex immunoassay utilizing patient-matched
Externí odkaz:
https://doaj.org/article/c6bfe0a2ff6e4c97bafc3c2d9739e9ab
Autor:
Yaw-Dong Lang, Hsin-Yi Chen, Chun-Ming Ho, Jou-Ho Shih, En-Chi Hsu, Roger Shen, Yu-Ching Lee, Jyun-Wei Chen, Cheng-Yen Wu, Hsi-Wen Yeh, Ruey-Hwa Chen, Yuh-Shan Jou
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
PSPC1 has a critical role in promoting EMT and metastasis. Here, the authors demonstrate that PSPC1 is the contextual determinant of the oncogenic switch of PTK6/β-catenin subcellular localizations to drive metastasis of hepatocellular carcinoma cel
Externí odkaz:
https://doaj.org/article/6ae4243b31584b1da82d9909f2146f87
Autor:
En-Chi Hsu, Samuel K. Kulp, Han-Li Huang, Huang-Ju Tu, Santosh B. Salunke, Nicholas J. Sullivan, Duxin Sun, Max S. Wicha, Charles L. Shapiro, Ching-Shih Chen
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 6, Pp 497-508 (2015)
Interleukin-6 (IL-6) and Notch signaling are important regulators of breast cancer stem cells (CSCs), which drive the malignant phenotype through self-renewal, differentiation, and development of therapeutic resistance. We investigated the role of in
Externí odkaz:
https://doaj.org/article/12a299e1a5344f7dbab1382a814fe3d7
Autor:
Su-Lin Lee, Chih-Chien Chou, Hsiao-Ching Chuang, En-Chi Hsu, Po-Chen Chiu, Samuel K Kulp, John C Byrd, Ching-Shih Chen
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67149 (2013)
Although the rictor-mTOR complex (mTORC2) has been shown to act as phosphoinositide-dependent kinase (PDK)2 in many cell types, other kinases have also been implicated in mediating Ser473-Akt phosphorylation. Here, we demonstrated the cell line speci
Externí odkaz:
https://doaj.org/article/b2c8fdea46454f19ba16c77a553e7492
Autor:
En-Chi Hsu, 許恩旗
92
Expression and distribution of core protein are tightly regulated during the progression of liver disease in patients with chronic HBV infection, suggestive of a role for core protein in the cytopathologic changes in persistent HBV infection.
Expression and distribution of core protein are tightly regulated during the progression of liver disease in patients with chronic HBV infection, suggestive of a role for core protein in the cytopathologic changes in persistent HBV infection.
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/26412758728481611943
Autor:
En‐Chi Hsu, Kuan‐Li Wu, Ying‐Ming Tsai, Mei‐Hsuan Lee, Ming‐Ju Tsai, Chia‐Yu Kuo, Yu‐Chuan Liu, Fu‐Wen Liang, Chih‐Jen Yang, Jen‐Yu Hung
Publikováno v:
The Kaohsiung Journal of Medical Sciences. 38:1001-1011
Lung squamous cell carcinoma (LUSC) represents a minor proportion of nonsmall cell lung cancer (NSCLC) harboring a poor prognosis. Herein, retrospective medical record research was performed to investigate real-world treatment patterns and identify t