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Impact of VKORC1, CYP2C9, and CYP4F2 Polymorphisms on Optimal Warfarin Dose: Does Ethnicity Matters?
Autor:
Soo J Kim, Long Z Guo, Kai Song, Moo H Kim, Kwang M Lee, Jia X Li, En Z Jin, Victor L. Serebruany
Publikováno v:
American journal of therapeutics. 28(4)
BACKGROUND Conventional anticoagulation with warfarin remains the cornerstone strategy for numerous preventive strategies. It is established that Asian patients require lower warfarin doses than Caucasians potentially attributing to the genetic polym