Zobrazeno 1 - 10
of 171
pro vyhledávání: '"En Qiang Chen"'
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background Direct high-quality evidence remains absent on the benefits of HBeAg-negative chronic hepatitis B patients (CHB) with normal alanine transaminase (ALT) and positive HBV DNA after nucleos(t)ide analogs (NAs) treatment. Methods This
Externí odkaz:
https://doaj.org/article/b0e70190a0aa4068b3cec3936707abd6
Autor:
Yong-Hong Wang, En-Qiang Chen
Publikováno v:
Gut and Liver, Vol 17, Iss 5, Pp 674-683 (2023)
Acute liver failure (ALF) is a severe liver disease syndrome with rapid deterioration and high mortality. Liver transplantation is the most effective treatment, but the lack of donor livers and the high cost of transplantation limit its broad applica
Externí odkaz:
https://doaj.org/article/3d81c73e12e245f886dcabfff7105654
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Background Stem cells play a therapeutic role mainly through immunoregulation. However, the immunomodulatory function of stem cells may be affected by inflammation-related factors in patients’ serum. Therefore, this study aims to investiga
Externí odkaz:
https://doaj.org/article/71156da45e424e1583e98d9468fb0203
Publikováno v:
Viruses, Vol 16, Iss 4, p 529 (2024)
Hepatitis B virus (HBV) infection is a serious global health problem, and chronic HBV infection significantly increases the risk of liver fibrosis, cirrhosis, and even hepatocellular carcinoma in patients. Current first-line therapeutics such as nucl
Externí odkaz:
https://doaj.org/article/5441d85801b142acbe61e5abebf2df05
Autor:
Fa- Da Wang, Jing Zhou, Lan-Qing Li, Yu-Jing Li, Meng-Lan Wang, Ya-Chao Tao, Dong-Mei Zhang, Yong-Hong Wang, En-Qiang Chen
Publikováno v:
Annals of Hepatology, Vol 28, Iss 5, Pp 101119- (2023)
Introduction and Objectives: Renal and bone impairment has been reported in chronic hepatitis B (CHB) patients receiving long-term tenofovir disoproxil fumarate (TDF) therapy. This study aimed to assess the incidence of renal and bone impairment in C
Externí odkaz:
https://doaj.org/article/bea6f3180920455282e46935635a9282
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
In recent years, liver experts have conducted in-depth discussions on whether it is necessary to expand the indication of antiviral therapy for patients with chronic hepatitis B (CHB). Currently, the guidelines are too strict in treating CHB patients
Externí odkaz:
https://doaj.org/article/8f934201ccb2417d9616fc0d42fa18b5
Publikováno v:
Frontiers in Public Health, Vol 10 (2023)
Because of insidious progression and no significant clinical symptoms at early stage, chronic hepatitis C (CHC) is often diagnosed after the occurrence of cirrhosis and hepatocellular carcinoma. Highly effective and low drug resistance of direct-acti
Externí odkaz:
https://doaj.org/article/2153b43717da4ffca7096dca02fc8937
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundAcute liver failure (ALF) and acute-on-chronic liver failure (ACLF) are the two most common subtypes of liver failure. They are both life-threatening clinical problems with high short-term mortality. Although liver transplantation is an eff
Externí odkaz:
https://doaj.org/article/33851b400623424685077438bbed9a9a
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2021)
Abstract Background Mesenchymal stem cells (MSCs) have to be expanded in vitro to reach a sufficient cell dose for the treatment of various diseases. During the process of expansion, some obstacles remain to be overcome. The purpose of this study was
Externí odkaz:
https://doaj.org/article/b8685c98fe4a42599c5d7d7a21b5a205
Autor:
Fa-Da Wang, Jing Zhou, Lan-Qing Li, Meng-Lan Wang, Ya-Cao Tao, Yong-Hong Wang, Dong-Mei Zhang, En-Qiang Chen
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Background and AimCessation of nucleos(t)ide analogs (NAs) therapy in patients with chronic hepatitis B (CHB) is uncommon. Although criteria for discontinuation appear in some guidelines, the indicators for assessing discontinuation of NAs are limite
Externí odkaz:
https://doaj.org/article/c5f0a65ec4304aeea1525fb19cdd7a38