Zobrazeno 1 - 10
of 14
pro vyhledávání: '"En Hyung Chang"'
Autor:
Adriana Osickova, Nataliya Balashova, Jiri Masin, Miroslav Sulc, Jana Roderova, Tomas Wald, Angela C. Brown, Evan Koufos, En Hyung Chang, Alexander Giannakakis, Edward T. Lally, Radim Osicka
Publikováno v:
Emerging Microbes and Infections, Vol 7, Iss 1, Pp 1-15 (2018)
Abstract Kingella kingae is a member of the commensal oropharyngeal flora of young children. Improvements in detection methods have led to the recognition of K. kingae as an emerging pathogen that frequently causes osteoarticular infections in childr
Externí odkaz:
https://doaj.org/article/0ad24cd2bb474f8e83870cb95223ed73
Autor:
Dae-Ho Kim, Jin-Sook Kim, Chang-Soo Mok, En-Hyung Chang, Jiwon Choi, Junsub Lim, Chul-Ho Kim, Ah-Reum Park, Yu-Jeong Bae, Bong-Seong Koo, Hyeon-Cheol Lee
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-22 (2022)
Abstract Immunotherapy has a number of advantages over traditional anti-tumor therapy but can cause severe adverse reactions due to an overactive immune system. In contrast, a novel metabolic treatment approach can induce metabolic vulnerability thro
Externí odkaz:
https://doaj.org/article/ca8568f3392a40a7a446857a66c224e7
Autor:
Angela C. Brown, En Hyung Chang
Publikováno v:
J Pharm Pharmacol
Objectives We and others have previously shown that epigallocatechin gallate (EGCg) inhibits the activity of an important virulence factor, leukotoxin (LtxA), produced by the oral bacterium Aggregatibacter actinomycetemcomitans, suggesting the potent
Autor:
Dae-Ho Kim, Jin-Sook Kim, Chang-Soo Mok, En-Hyung Chang, Jiwon Choi, Junsup Lim, Chul-Ho Kim, Ah-Reum Park, Yu-Jeong Bae, Bong-Seong Koo, Hyeon-Cheol Lee
Immunotherapy has a number of advantages over traditional anti-tumor therapy but can cause severe adverse reactions due to an overactive immune system. In contrast, a novel metabolic treatment approach can induce metabolic vulnerability through multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29a09a882828f78f4204da14ca131cbf
https://doi.org/10.21203/rs.3.rs-1560688/v1
https://doi.org/10.21203/rs.3.rs-1560688/v1
Publikováno v:
Mol Oral Microbiol
The oral pathogen, Aggregatibacter actinomycetemcomitans, produces a number of virulence factors, including a leukotoxin (LtxA), which specifically kills human white blood cells, to provide a colonization advantage to the bacterium. Strains of A. act
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1863:191-198
Background Catechins, polyphenols derived from tea leaves, have been shown to have antibacterial properties, through direct killing of bacteria as well as through inhibition of bacterial toxin activity. In particular, certain catechins have been show
Publikováno v:
J Vis Exp
The cell wall of Gram-negative bacteria consists of an inner (cytoplasmic) and outer membrane (OM), separated by a thin peptidoglycan layer. Throughout growth, the outer membrane can bleb to form spherical outer membrane vesicles (OMVs). These OMVs a
Autor:
Jiri Masin, Radim Osicka, Tomas Wald, Adriana Osickova, Edward T. Lally, En Hyung Chang, Evan Koufos, Alexander Giannakakis, Jana Roderova, Miroslav Šulc, Nataliya V. Balashova, Angela C. Brown
Publikováno v:
Emerging Microbes & Infections
Emerging Microbes and Infections, Vol 7, Iss 1, Pp 1-15 (2018)
Emerging Microbes and Infections, Vol 7, Iss 1, Pp 1-15 (2018)
Kingella kingae is a member of the commensal oropharyngeal flora of young children. Improvements in detection methods have led to the recognition of K. kingae as an emerging pathogen that frequently causes osteoarticular infections in children and a
Publikováno v:
ACS infectious diseases. 4(7)
The Gram-negative bacterium Aggregatibacter actinomycetemcomitans, commonly associated with localized aggressive periodontitis (LAP), secretes an RTX (repeats-in-toxin) protein leukotoxin (LtxA) that targets human white blood cells, an interaction th
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1839:1323-1329
Background Hydroxymethylation of DNA at the C5 position of cytosine (5hmC) is recognized as an important epigenetic mark. The molecular role of 5hmC in gene regulation, however, is not well understood. Methods We studied the effects of 5-hydroxymethy