Zobrazeno 1 - 4 of 4 pro vyhledávání: '"Emst, L. van"'
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Diminished proteasomal degradation results in accumulation of Gfi1 protein in monocytes
Autor: Marteijn, J.A.F., Meer, L.T. van der, Emst, L. van, Jansen, P., Witte, T.J.M. de, Jansen, J.H., Reijden, B.A. van der
Publikováno v: Blood, 109, 1, pp. 100-108
Blood, 109, 100-108
Gfi1 is a transcriptional repressor essential during myeloid differentiation. Gfi1−/− mice exhibit a block in myeloid differentiation resulting in the accumulation of an immature myelo-monocytic cell population and the complete absence of mature
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9155a13d0d7901471c589b20906d1305
https://doi.org/10.1182/blood-2006-02-003590
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4
The origin and nature of tightly clustered BTG1 deletions in precursor B-cell acute lymphoblastic leukemia support a model of multiclonal evolution
Autor: Waanders, E., Scheijen, B., Meer, L.T. van der, Reijmersdal, S.V. van, Emst, L. van, Kroeze, Y.L., Sonneveld, E., Hoogerbrugge, P.M., Geurts van Kessel, A., Leeuwen, F.N. van, Kuiper, R.P.
Publikováno v: Plos Genetics, 8, 2, pp. e1002533-e1002533
Plos Genetics, 8, e1002533-e1002533
Contains fulltext : 109893.pdf (Publisher’s version ) (Open Access) Recurrent submicroscopic deletions in genes affecting key cellular pathways are a hallmark of pediatric acute lymphoblastic leukemia (ALL). To gain more insight into the mechanism
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::bdc322e5da10308c2effd1c5149bd2d9
https://hdl.handle.net/2066/109893
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