Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Emre Pekbilir"'
Autor:
Arman Çakar, Emre Pekbilir, Serdar Ceylaner, Hacer Durmuş, Esra Battaloğlu, Umut Şahin, Yeşim Parman
Publikováno v:
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. :1-4
Autor:
Bilgül Mete, Emre Pekbilir, Bilge Nur Bilge, Panagiota Georgiadou, Elif Çelik, Tolga Sutlu, Fehmi Tabak, Umut Sahin
Publikováno v:
Life Science Alliance. 5:e202101103
During infection, the human immunodeficiency virus type 1 (HIV-1) manipulates host cell mechanisms to its advantage, thereby controlling its replication or latency, and evading immune responses. Sumoylation is an essential post-translational modifica
Autor:
Tunahan Ergünay, Özgecan Ayhan, Arda B Celen, Panagiota Georgiadou, Emre Pekbilir, Yusuf T Abaci, Duygu Yesildag, Mandy Rettel, Ulduz Sobhiafshar, Anna Ogmen, NC Tolga Emre, Umut Sahin
Publikováno v:
Life Science Alliance
Cas9 is sumoylated and ubiquitylated in human cells. K848 is the major SUMO2/3 modification site, but multiple lysines are ubiquitylated, precipitating proteasomal degradation. Preventing Cas9 sumoylation by K848 ablation or by pharmacologic means re