Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Emrah Altındiş"'
Autor:
Martina Chrudinová, Nicholas S. Kirk, Aurelien Chuard, Hari Venugopal, Fa Zhang, Marta Lubos, Vasily Gelfanov, Terezie Páníková, Lenka Žáková, Julianne Cutone, Matthew Mojares, Richard DiMarchi, Jiří Jiráček, Emrah Altindis
Publikováno v:
Molecular Metabolism, Vol 80, Iss , Pp 101863- (2024)
Objective: The insulin/IGF superfamily is conserved across vertebrates and invertebrates. Our team has identified five viruses containing genes encoding viral insulin/IGF-1 like peptides (VILPs) closely resembling human insulin and IGF-1. This study
Externí odkaz:
https://doaj.org/article/7c5f60a2f83f44fdb26861620a039b02
Publikováno v:
Authoritarianism and Resistance in Turkey ISBN: 9783319767048
Proletarianization in the Ottoman Empire came much later than in Europe. At the beginning of the 20th century, the percentage of paid workers among the labor force was around 1%, numbering around 200–300 thousand. To understand this quantitative pi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3f73c40815954b0c70fba288e1d8a60
https://doi.org/10.1007/978-3-319-76705-5_14
https://doi.org/10.1007/978-3-319-76705-5_14
This book offers an in-depth overview of Turkish history and politics essential for understanding contemporary Turkey. It presents an analysis on a number of key issues from gender inequality to Islamism to urban regeneration. Based on interviews wit
Autor:
Khyati Girdhar, Yusuf Dogus Dogru, Qian Huang, Yi Yang, Vladimir Tolstikov, Amol Raisingani, Martina Chrudinova, Jaewon Oh, Kristina Kelley, Jonas F. Ludvigsson, Michael A. Kiebish, Noah W. Palm, Johnny Ludvigsson, Emrah Altindis
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-20 (2023)
Abstract Background Celiac disease (CD) is an autoimmune disorder triggered by gluten consumption. Almost all CD patients possess human leukocyte antigen (HLA) DQ2/DQ8 haplotypes; however, only a small subset of individuals carrying these alleles dev
Externí odkaz:
https://doaj.org/article/90ee455b198944da9eb5694319c0b5a9
Autor:
Francois Moreau, Nicholas S. Kirk, Fa Zhang, Vasily Gelfanov, Edward O. List, Martina Chrudinová, Hari Venugopal, Michael C. Lawrence, Veronica Jimenez, Fatima Bosch, John J. Kopchick, Richard D. DiMarchi, Emrah Altindis, C. Ronald Kahn
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The authors previously identified a family of viral insulin-like peptides (VILPs) with high homology to human insulin/IGF−1. Here, they report that one of these VILPs exhibits antagonist properties associated with a unique conformation of the IGF1R
Externí odkaz:
https://doaj.org/article/bfab9e0851234eeaa306dca00cc42caa
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101316- (2021)
Objective: Natural sources of molecular diversity remain of utmost importance as a reservoir of proteins and peptides with unique biological functions. We recently identified such a family of viral insulin-like peptides (VILPs). We sought to advance
Externí odkaz:
https://doaj.org/article/f3711ebfbba144dcbe3bf20dd8d9d17b
Autor:
Martina Chrudinová, François Moreau, Hye Lim Noh, Terezie Páníková, Lenka Žáková, Randall H. Friedline, Francisco A. Valenzuela, Jason K. Kim, Jiří Jiráček, C. Ronald Kahn, Emrah Altindis
Publikováno v:
Molecular Metabolism, Vol 44, Iss , Pp 101121- (2021)
Objective: Members of the insulin/insulin-like growth factor (IGF) superfamily are well conserved across the evolutionary tree. We recently showed that four viruses in the Iridoviridae family possess genes that encode proteins highly homologous to hu
Externí odkaz:
https://doaj.org/article/6021b0b3fea045b7b555497608ce50e0
Autor:
Sandra Dedrick, Bharathi Sundaresh, Qian Huang, Claudia Brady, Tessa Yoo, Catherine Cronin, Caitlin Rudnicki, Michael Flood, Babak Momeni, Johnny Ludvigsson, Emrah Altindis
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Type 1 Diabetes (T1D) is regarded as an autoimmune disease characterized by insulin deficiency resulting from destruction of pancreatic β-cells. The incidence rates of T1D have increased worldwide. Over the past decades, progress has been made in un
Externí odkaz:
https://doaj.org/article/35213e86e1404a6eb370c51904c19668
Autor:
Shiho Fujisaka, Julian Avila-Pacheco, Marion Soto, Aleksandar Kostic, Jonathan M. Dreyfuss, Hui Pan, Siegfried Ussar, Emrah Altindis, Ning Li, Lynn Bry, Clary B. Clish, C. Ronald Kahn
Publikováno v:
Cell Reports, Vol 22, Iss 11, Pp 3072-3086 (2018)
Summary: Diet, genetics, and the gut microbiome are determinants of metabolic status, in part through production of metabolites by the gut microbiota. To understand the mechanisms linking these factors, we performed LC-MS-based metabolomic analysis o
Externí odkaz:
https://doaj.org/article/60ccf368e5734442a9a4679d88badbcc
Publikováno v:
mBio, Vol 6, Iss 2 (2015)
ABSTRACT The type VI secretion system (T6SS) is a dynamic macromolecular organelle that many Gram-negative bacteria use to inhibit or kill other prokaryotic or eukaryotic cells. The toxic effectors of T6SS are delivered to the prey cells in a contact
Externí odkaz:
https://doaj.org/article/7402f6ee3e85424d83ea9023fdbab745