Accumulation of copy-back viral genomes during respiratory syncytial virus infection is preceded by diversification of the copy-back viral genome population followed by selection

Autor: Sébastien A. Felt, Emna Achouri, Sydney R. Faber, Carolina B. López

Publikováno v: Virus Evolution. 8

RNA viruses generate nonstandard viral genomes during their replication, including viral genomes of the copy-back (cbVGs) type that cannot replicate in the absence of a standard virus. cbVGs play a crucial role in shaping virus infection outcomes due

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e69103f28dcec93392674ef62e8beadf
https://doi.org/10.1093/ve/veac091

Genome analysis of coxsackievirus B1 isolates during the consecutive alternating administration course of triple antiviral combination in newborn mice

Autor: Petar Grozdanov, Ivanka Nikolova, Adelina Stoyanova, Patsy M. Polston, Angel S. Galabov, Francis Delpeyroux, Emna Achouri, Marie-Line Joffret

Publikováno v: Antiviral Chemistry & Chemotherapy, Vol 28 (2020)
Antiviral Chemistry and Chemotherapy
Antiviral Chemistry and Chemotherapy, International Medical Press, 2020, 28, pp.204020662090606. ⟨10.1177/2040206620906061⟩
Antiviral Chemistry & Chemotherapy
Antiviral Chemistry and Chemotherapy, 2020, 28, pp.204020662090606. ⟨10.1177/2040206620906061⟩

International audience; Background: We developed a new approach for the treatment of enterovirus infections, the consecutive alternating administration (CAA) of a combination of enterovirus inhibitors. On the model of coxsackievirus B1 (CVB1) in mice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a677d87b982dd78cbce9350094b8657
https://doaj.org/article/e75ccecaa24b4df9ba807f3e18030382

Gut Microbial Diversity Is Reduced in Smokers with Crohn's Disease

Autor: Jorrit L. Opstelten, Jonathan Plassais, Bas Oldenburg, Emna Achouri, Peter D. Siersema, Alessandra C. L. Cervino, Saskia W.C. van Mil, Matthieu Pichaud

Publikováno v: Inflammatory Bowel Diseases, 22, 9, pp. 2070-7
Inflammatory Bowel Diseases, 22, 2070-7
Inflammatory bowel diseases, 22(9), 2070. John Wiley and Sons Inc.
Inflammatory Bowel Diseases

Article first published online 10 August 2016.
Background: Smoking has a negative impact on Crohn's disease (CD), but the mechanisms underlying this association are unclear. We compared the gut microbiota composition of smoking with nonsmoking p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558e3eb84808a7eff1f7b49cc8c097bb
https://hdl.handle.net/2066/172646

Copy-back viral genomes induce a cellular stress response that interferes with viral protein expression without affecting antiviral immunity.

Autor: González Aparicio, Lavinia J.¹ (AUTHOR), Yang, Yanling¹ (AUTHOR), Hackbart, Matthew¹ (AUTHOR), López, Carolina B.¹ (AUTHOR) clopezzalaquett@wustl.edu

Publikováno v: PLoS Biology. 11/20/2023, Vol. 21 Issue 11, p1-26. 26p.

Stunted childhood growth is associated with decompartmentalization of the gastrointestinal tract and overgrowth of oropharyngeal taxa.

Autor: Morgan, Michael J., Fitzwalter, Brent E., Owens, Charles R., Powers, Rani K., Sottnik, Joseph L., Gamez, Graciel, Costello, James C., Theodorescu, Dan, Thorburn, Andrew

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; 9/4/2018, Vol. 115 Issue 36, pE8489-E8498, 10p