Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Emmy W Verschuren"'
Autor:
Akseli Hemminki, Víctor Cervera-Carrascón, Riikka Havunen, Otto Hemminki, Anna Kanerva, João Manuel Santos, Camilla Heiniö, Jari Räsänen, Suvi Sorsa, Santeri A Pakola, James Clubb, Tatiana V Kudling, Susanna AM Grönberg-Vähä-Koskela, Victor Arias, Dafne Alves Quixabeira, Iris Lähdeniemi, Eva Sutinen, Kristian Borenius, Mikko Mäyränpää, Eero Altonen, Emmy W Verschuren, Ilkka Ilonen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/b558acb986684d68b325206f8f881136
Autor:
Sarang S. Talwelkar, Iris A.K. Lähdeniemi, Mikko I. Mäyränpää, Annabrita Hemmes, Nora Linnavirta, Jari Räsänen, Aija Knuuttila, Krister Wennerberg, Emmy W. Verschuren
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101720- (2022)
Summary: Drug sensitivity data acquired from solid tumor-derived cultures are often unsuitable for personalized treatment guidance due to the lengthy turnaround time. Here, we present a protocol for determining ex vivo drug sensitivities using fresh
Externí odkaz:
https://doaj.org/article/006c6459adf0456781a8ab0e155bc7a4
Autor:
Ashwini S. Nagaraj, Jenni Lahtela, Annabrita Hemmes, Teijo Pellinen, Sami Blom, Jennifer R. Devlin, Kaisa Salmenkivi, Olli Kallioniemi, Mikko I. Mäyränpää, Katja Närhi, Emmy W. Verschuren
Publikováno v:
Cell Reports, Vol 18, Iss 3, Pp 673-684 (2017)
Lung cancers exhibit pronounced functional heterogeneity, confounding precision medicine. We studied how the cell of origin contributes to phenotypic heterogeneity following conditional expression of KrasG12D and loss of Lkb1 (Kras;Lkb1). Using proge
Externí odkaz:
https://doaj.org/article/4865c03d589649f090200e998d1e2cd4
Autor:
Emmy W. Verschuren, Krister Wennerberg, Mikko I. Mäyränpää, Kaisa Salmenkivi, Pipsa Saharinen, Elina A. Kiss, Swapnil Potdar, Annabrita Hemmes, Jennifer R. Devlin, Ashwini S. Nagaraj, Sarang S. Talwelkar
Table_S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27859c01a5a1785161bc7a7bd455ec8a
https://doi.org/10.1158/1535-7163.22509207.v1
https://doi.org/10.1158/1535-7163.22509207.v1
Autor:
Emmy W. Verschuren, Krister Wennerberg, Mikko I. Mäyränpää, Kaisa Salmenkivi, Pipsa Saharinen, Elina A. Kiss, Swapnil Potdar, Annabrita Hemmes, Jennifer R. Devlin, Ashwini S. Nagaraj, Sarang S. Talwelkar
Supplementary text and figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25da8709577071f02aaeaf9cd8b88369
https://doi.org/10.1158/1535-7163.22509210.v1
https://doi.org/10.1158/1535-7163.22509210.v1
Autor:
Emmy W. Verschuren, Krister Wennerberg, Mikko I. Mäyränpää, Kaisa Salmenkivi, Pipsa Saharinen, Elina A. Kiss, Swapnil Potdar, Annabrita Hemmes, Jennifer R. Devlin, Ashwini S. Nagaraj, Sarang S. Talwelkar
Most non–small cell lung cancers (NSCLC) contain nontargetable mutations, including KRAS, TP53, or STK11/LKB1 alterations. By coupling ex vivo drug sensitivity profiling with in vivo drug response studies, we aimed to identify drug vulnerabilities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d26d521c92c9d7c4073c63d907f5285
https://doi.org/10.1158/1535-7163.c.6539226.v1
https://doi.org/10.1158/1535-7163.c.6539226.v1
Autor:
Tomi P. Mäkelä, Yan Yan, Benoit Viollet, Emmy W. Verschuren, Marc Foretz, Sarang S. Talwelkar, Ashwini S. Nagaraj, Kari Vaahtomeri, Iris P.L. Wong, Eva Domènech-Moreno, Sushil Tripathi, Pekka Päivinen, Yajing Gao
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf7d78d002e222ae30eb969056b2dcf
https://doi.org/10.1158/1078-0432.22483148.v1
https://doi.org/10.1158/1078-0432.22483148.v1
Autor:
Juha Klefström, Emmy W. Verschuren, Panu E. Kovanen, Caj Haglund, Katja Närhi, Johanna I. Englund, Denis Belitškin, Shishir M. Pant, Topi A. Tervonen
Ras proteins play a causal role in human cancer by activating multiple pathways that promote cancer growth and invasion. However, little is known about how Ras induces the first diagnostic features of invasion in solid tumors, including loss of epith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ed27c78bf69ac46bd29a52cb8d6c245
https://doi.org/10.1158/0008-5472.c.6513103.v1
https://doi.org/10.1158/0008-5472.c.6513103.v1
Autor:
Tomi P. Mäkelä, Yan Yan, Benoit Viollet, Emmy W. Verschuren, Marc Foretz, Sarang S. Talwelkar, Ashwini S. Nagaraj, Kari Vaahtomeri, Iris P.L. Wong, Eva Domènech-Moreno, Sushil Tripathi, Pekka Päivinen, Yajing Gao
Supplementary Tables S1-S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f3b60ddeb33394f249a620d2b64aad
https://doi.org/10.1158/1078-0432.22483145.v1
https://doi.org/10.1158/1078-0432.22483145.v1
Autor:
Tomi P. Mäkelä, Yan Yan, Benoit Viollet, Emmy W. Verschuren, Marc Foretz, Sarang S. Talwelkar, Ashwini S. Nagaraj, Kari Vaahtomeri, Iris P.L. Wong, Eva Domènech-Moreno, Sushil Tripathi, Pekka Päivinen, Yajing Gao
Purpose:Mutations in STK11 (LKB1) occur in 17% of lung adenocarcinoma (LUAD) and drive a suppressive (cold) tumor immune microenvironment (TIME) and resistance to immunotherapy. The mechanisms underpinning the establishment and maintenance of a cold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ed9939b234523c2dcc74834050a75e
https://doi.org/10.1158/1078-0432.c.6531086.v1
https://doi.org/10.1158/1078-0432.c.6531086.v1