Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Emmi Pakarinen"'
Autor:
Emmi Pakarinen, Päivi Lindholm
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized by gradual loss of midbrain dopamine neurons, leading to impaired motor function. Preclinical studies have indicated cerebral dopamine neurotrophic factor (CDNF) and
Externí odkaz:
https://doaj.org/article/ab1e912e62f74c58aa680c30a2f99210
Autor:
Maria Lindahl, Alcmène Chalazonitis, Erik Palm, Emmi Pakarinen, Tatiana Danilova, Tuan D. Pham, Wanda Setlik, Meenakshi Rao, Vootele Võikar, Jatta Huotari, Jaakko Kopra, Jaan-Olle Andressoo, Petteri T. Piepponen, Mikko Airavaara, Anne Panhelainen, Michael D. Gershon, Mart Saarma
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
Cerebral dopamine neurotrophic factor (CDNF) is neuroprotective for nigrostriatal dopamine neurons and restores dopaminergic function in animal models of Parkinson's disease (PD). To understand the role of CDNF in mammals, we generated CDNF knockout
Externí odkaz:
https://doaj.org/article/69ba4e0c23f74002a965644692bf2a73
Autor:
Tatiana Danilova, Emilia Galli, Emmi Pakarinen, Erik Palm, Päivi Lindholm, Mart Saarma, Maria Lindahl
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Mesencephalic astrocyte-derived neurotrophic factor (MANF) and cerebral dopamine neurotrophic factor (CDNF) form a family of atypical growth factors discovered for their neuroprotective properties in the central nervous system (CNS) in animal models
Externí odkaz:
https://doaj.org/article/8030f1f6315340aba45a979396c93b13
Autor:
Ave Eesmaa, Li-Ying Yu, Helka Göös, Tatiana Danilova, Kristofer Nõges, Emmi Pakarinen, Markku Varjosalo, Maria Lindahl, Päivi Lindholm, Mart Saarma
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 9489
Cerebral dopamine neurotrophic factor (CDNF) is a neurotrophic factor that has beneficial effects on dopamine neurons in both in vitro and in vivo models of Parkinson’s disease (PD). CDNF was recently tested in phase I-II clinical trials for the tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60002108fd147bf74b4744aaf906e171
http://hdl.handle.net/10138/347997
http://hdl.handle.net/10138/347997
Cerebral dopamine neurotrophic factor (CDNF) and mesencephalic astrocyte-derived neurotrophic factor (MANF) display cytoprotective effects in animal models of neurodegenerative diseases. These endoplasmic reticulum (ER)-resident proteins belong to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccfc65d3d207980a4a7aeb0e72d43b61
http://hdl.handle.net/10138/341650
http://hdl.handle.net/10138/341650
Autor:
Mart Saarma, Kuu Ikäheimo, Anni Herranen, Tuuli Lankinen, Bernd Fritzsch, Emmi Pakarinen, Ulla Pirvola, Maria Lindahl
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 2, Pp 1-12 (2020)
Cell Death and Disease, Vol 11, Iss 2, Pp 1-12 (2020)
The non-conventional neurotrophic factor mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER)-resident protein that promotes ER homeostasis. MANF has a cytoprotective function, shown in the central nervous syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1518ef830c09a892ebf580318e90c6
https://doi.org/10.1038/s41419-020-2286-6
https://doi.org/10.1038/s41419-020-2286-6
Autor:
Tatiana Danilova, Jaakko Kopra, Mikko Airavaara, Jaan-Olle Andressoo, Alcmène Chalazonitis, Wanda Setlik, Vootele Voikar, Petteri Piepponen, Mart Saarma, Maria Lindahl, Meenakshi Rao, Tuan D. Pham, Erik Palm, Emmi Pakarinen, Jatta Huotari, Michael D. Gershon, Anne Panhelainen
Publikováno v:
Neurobiology of Disease, Vol 134, Iss, Pp-(2020)
Neurobiology of disease
Neurobiology of disease
Cerebral dopamine neurotrophic factor (CDNF) is neuroprotective for nigrostriatal dopamine neurons and restores dopaminergic function in animal models of Parkinson's disease (PD). To understand the role of CDNF in mammals, we generated CDNF knockout
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af73f486e2b4a0501a28427cc222ad30
http://www.sciencedirect.com/science/article/pii/S0969996119303717
http://www.sciencedirect.com/science/article/pii/S0969996119303717
Autor:
Mart Saarma, Piotr Chmielarz, Petteri Piepponen, Maria Lindahl, Mikko Airavaara, Emmi Pakarinen, Vootele Voikar, Tatiana Danilova
Publikováno v:
eNeuro
Visual Abstract
Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER) localized protein that regulates ER homeostasis and unfolded protein response (UPR). The biology of endogenous MANF in the mammalian brai
Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER) localized protein that regulates ER homeostasis and unfolded protein response (UPR). The biology of endogenous MANF in the mammalian brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f44c608f1e13feec51aaa93aa130e1a
http://hdl.handle.net/10138/318508
http://hdl.handle.net/10138/318508
Publikováno v:
Bioscience Reports
The plasma membrane consists of a variety of discrete domains differing from the surrounding membrane in composition and properties. Selective partitioning of protein to these microdomains is essential for membrane functioning and integrity. Studying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71aa0a8930eac25428ec92924c29584
https://doi.org/10.1042/bsr20191290
https://doi.org/10.1042/bsr20191290
Autor:
Päivi Lindholm, Mart Saarma, Emmi Pakarinen, Emilia Galli, Maria Lindahl, Tatiana Danilova, Erik Palm
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 10 (2019)
Frontiers in Endocrinology, Vol 10 (2019)
Mesencephalic astrocyte-derived neurotrophic factor (MANF) and cerebral dopamine neurotrophic factor (CDNF) form a family of atypical growth factors discovered for their neuroprotective properties in the central nervous system (CNS) in animal models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d75ec54c3874c97374fc113fc3c72ee0
http://europepmc.org/articles/PMC6851024
http://europepmc.org/articles/PMC6851024