Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Emmeline C Academia"'
Autor:
Daniel S Evans, Monique N O'Leary, Ryan Murphy, Minna Schmidt, Kristin Koenig, Michael Presley, Brittany Garrett, Ha‐Neui Kim, Li Han, Emmeline C Academia, Matt J Laye, Daniel Edgar, Christopher A Zambataro, Tracey Barhydt, Colleen M Dewey, Jarrott Mayfield, Joy Wilson, Silvestre Alavez, Mark Lucanic, Brian K Kennedy, Maria Almeida, Julie K Andersen, Pankaj Kapahi, Gordon J Lithgow, Simon Melov
Publikováno v:
JBMR Plus, Vol 5, Iss 3, Pp n/a-n/a (2021)
ABSTRACT Aging is characterized by systemic declines in tissue and organ functions. Interventions that slow these declines represent promising therapeutics to protect against age‐related disease and improve the quality of life. In this study, sever
Externí odkaz:
https://doaj.org/article/1488f0e2d6454063828ddeb29690b6a6
Autor:
Monique N O'Leary, Katherine H Schreiber, Yong Zhang, Anne-Cécile E Duc, Shuyun Rao, J Scott Hale, Emmeline C Academia, Shreya R Shah, John F Morton, Carly A Holstein, Dan B Martin, Matt Kaeberlein, Warren C Ladiges, Pamela J Fink, Vivian L Mackay, David L Wiest, Brian K Kennedy
Publikováno v:
PLoS Genetics, Vol 9, Iss 8, p e1003708 (2013)
Most yeast ribosomal protein genes are duplicated and their characterization has led to hypotheses regarding the existence of specialized ribosomes with different subunit composition or specifically-tailored functions. In yeast, ribosomal protein gen
Externí odkaz:
https://doaj.org/article/18c13070d632430da79e5d9b4c32c8dc
Autor:
Judith Campisi, Hyman Muss, Norman E. Sharpless, Daohong Zhou, Simon Melov, Brian K. Kennedy, Alain de Bruin, Boshi Wang, Alexis Valdovinos, Sumner Kilmarx, Emmeline C. Academia, Shani Alston, Allison M. Deal, Natalia Mitin, Catherine Le, Kristin Koenig, Fatouma Alimirah, Su Liu, Lijian Shao, Jianhui Chang, Monique N. O'Leary, Marco Demaria
Supplementary Figures S1 - S10, Tables S1 - S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6bd22656c0abacbc1cfe8254992355
https://doi.org/10.1158/2159-8290.22532077.v1
https://doi.org/10.1158/2159-8290.22532077.v1
Autor:
Paul M. Reynolds, Christian J. Gabriel, Emmeline C. Academia, Amanda Mueller, Karsten Bartels, Kerry Schwarz, Robert J. Valuck
Publikováno v:
Annals of Pharmacotherapy. 54:1065-1072
Background: Opioids are utilized for pain management during and after mechanical ventilation in the intensive care unit (ICU). Objective: The purpose of this study was to determine the percentage of potentially unnecessary opioid prescriptions on dis
Autor:
Lily Y Jia, Tuyen Yankama, Emmeline C Academia, Caroline M Mejías-De Jesús, Jinkyu Lee, Chirag Patel, Julia S Stevens
Publikováno v:
Journal of managed carespecialty pharmacy. 27(10)
BACKGROUND: Oral oncolytics are becoming increasingly common in the treatment of solid and hematological malignancies. Medication adherence is especially important to ensure adequate drug levels to...
Publikováno v:
Journal of pharmacy practice. 35(3)
Background: Early appropriate antibiotic administration is associated with improved outcomes in infectious illnesses. During drug shortages in 2017, the American Society of Health-System Pharmacists recommended intravenous push (IVP) administration o
Autor:
Natalia Mitin, Judith Campisi, Alexis Valdovinos, Norman E. Sharpless, Jianhui Chang, Boshi Wang, Hyman B. Muss, Shani Alston, Kristin Koenig, Allison M. Deal, Brian K. Kennedy, Alain de Bruin, Sumner Kilmarx, Fatouma Alimirah, Catherine H. Le, Simon Melov, Monique N. O’Leary, Lijian Shao, Emmeline C. Academia, Daohong Zhou, Su Liu, Marco Demaria
Publikováno v:
Demaria, M; O’Leary, MN; Chang, J; Shao, L; Liu, S; Alimirah, F; et al.(2017). Cellular senescence promotes adverse effects of chemotherapy and cancer relapse. Cancer Discovery, 7(2), 165-176. doi: 10.1158/2159-8290.CD-16-0241. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/54h8z0j1
Cancer discovery, vol 7, iss 2
Cancer discovery, 7(2), 165-176. AMER ASSOC CANCER RESEARCH
Cancer discovery, vol 7, iss 2
Cancer discovery, 7(2), 165-176. AMER ASSOC CANCER RESEARCH
Cellular senescence suppresses cancer by irreversibly arresting cell proliferation. Senescent cells acquire a proinflammatory senescence-associated secretory phenotype. Many genotoxic chemotherapies target proliferating cells nonspecifically, often w
Publikováno v:
Journal of the Advanced Practitioner in Oncology
The phosphoinositide 3-kinase (PI3K) pathway plays a primary role in cellular proliferation and metabolism. Inhibition of the PI3K pathway is an emerging area of drug development and cancer research. Idelalisib, copanlisib, and duvelisib are currentl
Autor:
Lizbeth Leon Martinez, Somasish Ghosh Dastidar, Christian Michael Viray, Albert R. La Spada, Elizabeth Del Greco, Emmeline C. Academia, Travis D. Ashe, Joanna M. Sitzmann, Kaili Lia Carr, Ariana A. Rodriguez, Brian K. Kennedy, Brian Kaplowitz, Shih-Yin Tsai
Publikováno v:
Cell Reports, Vol 16, Iss 7, Pp 1903-1914 (2016)
SummaryObesity is a major risk factor driving the global type II diabetes pandemic. However, the molecular factors linking obesity to disease remain to be elucidated. Gender differences are apparent in humans and are also observed in murine models. H
Autor:
Brittany J. Garrett, Dominic J. Withers, Amanda M Bair, Joy A. Wilson, Delana M Miller, Erin M Stewart, Chen-Yu Liao, Sydney S. Anderson, Nicole H. Chicoine, Gabriella Tannady, Charlotte S Kwok, Emmeline C. Academia, Jarrott R. Mayfield, Brian K. Kennedy, Stuart S. Adamson, Yueh-Mei Hsu, Junying Wang
Publikováno v:
Cell Discovery
The mechanistic target of rapamycin (mTOR) signaling pathway plays a central role in aging and a number of different disease states. Rapamycin, which suppresses activity of the mTOR complex 1 (mTORC1), shows preclinical (and sometimes clinical) effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7770dc559fad04622240caaa20a99d3f
http://hdl.handle.net/10044/1/54238
http://hdl.handle.net/10044/1/54238