Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Emmarose McCoig"'
Autor:
Nicolas H. Piguel, Shaun S. Sanders, Francesca I. De Simone, Maria D. Martin-de-Saavedra, Emmarose McCoig, Leonardo E. Dionisio, Katharine R. Smith, Gareth M. Thomas, Peter Penzes
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
IntroductionAnkG, encoded by the ANK3 gene, is a multifunctional scaffold protein with complex isoform expression: the 480 and 270 kDa isoforms have roles at the axon initial segment and node of Ranvier, whereas the 190 kDa isoform (AnkG-190) has an
Externí odkaz:
https://doaj.org/article/52a343df27d8423883a4ff7c95f0ced1
Autor:
Zhixiong Sun, Xiguang Xu, Jianlin He, Alexander Murray, Ming-an Sun, Xiaoran Wei, Xia Wang, Emmarose McCoig, Evan Xie, Xi Jiang, Liwu Li, Jinsong Zhu, Jianjun Chen, Alexei Morozov, Alicia M. Pickrell, Michelle H. Theus, Hehuang Xie
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
It is unclear why neuronal activity induced methylation changes are limited to specific loci in the genome. Here, authors show that the DNA demethylation enzyme, TET1, gains its specificity via the interaction with EGR1, a sequence specific DNA bindi
Externí odkaz:
https://doaj.org/article/833197c688f54d60ab4edcc1365addf1
Autor:
M Dolores, Martín-de-Saavedra, Marc, Dos Santos, Lorenza, Culotta, Olga, Varea, Benjamin P, Spielman, Euan, Parnell, Marc P, Forrest, Ruoqi, Gao, Sehyoun, Yoon, Emmarose, McCoig, Hiba A, Jalloul, Kristoffer, Myczek, Natalia, Khalatyan, Elizabeth A, Hall, Liam S, Turk, Antonio, Sanz-Clemente, Davide, Comoletti, Stefan F, Lichtenthaler, Jeffrey S, Burgdorf, Maria V, Barbolina, Jeffrey N, Savas, Peter, Penzes
Publikováno v:
Neuron
While many neuronal, membrane proteins undergo proteolytic cleavage, little is known about the biological significance of neuronal ectodomain shedding (ES). Here, we show that the neuronal sheddome is detectable in human cerebrospinal fluid (hCSF) an
Autor:
M. Dolores Martín-de-Saavedra, Marc Dos Santos, Lorenza Culotta, Olga Varea, Benjamin P. Spielman, Euan Parnell, Marc P. Forrest, Ruoqi Gao, Sehyoun Yoon, Emmarose McCoig, Hiba A. Jalloul, Kristoffer Myczek, Natalia Khalatyan, Elizabeth A. Hall, Liam S. Turk, Antonio Sanz-Clemente, Davide Comoletti, Stefan F. Lichtenthaler, Jeffrey S. Burgdorf, Maria V. Barbolina, Jeffrey N. Savas, Peter Penzes
Publikováno v:
Neuron 110(4), 627-643.e9 (2022). doi:10.1016/j.neuron.2021.11.025
Although many neuronal membrane proteins undergo proteolytic cleavage, little is known about the biological significance of neuronal ectodomain shedding (ES). Here, we show that the neuronal sheddome is detectable in human cerebrospinal fluid (hCSF)