Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Emmanuelle Wirth"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract IL-17A and IL-17F are prominent members of the IL-17 family of cytokines that regulates both innate and adaptive immunity. IL-17A has been implicated in chronic inflammatory and autoimmune diseases, and anti-IL-17A antibodies have shown rema
Externí odkaz:
https://doaj.org/article/62586932f66c4a62852c9be2789af9d4
Autor:
Arnaud Goepfert, Carmen Barske, Sylvie Lehmann, Emmanuelle Wirth, Joschka Willemsen, Johann E. Gudjonsson, Nicole L. Ward, Mrinal K. Sarkar, René Hemmig, Frank Kolbinger, Jean-Michel Rondeau
Publikováno v:
Cell Reports. 41:111489
Signaling through innate immune receptors such as the Toll-like receptor (TLR)/interleukin-1 receptor (IL-1R) superfamily proceeds via the assembly of large membrane-proximal complexes or "signalosomes." Although structurally distinct, the IL-17 rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b652cdfbf1475a7f2198c0c9b3810c4
https://doi.org/10.1016/j.celrep.2022.111489
https://doi.org/10.1016/j.celrep.2022.111489
Autor:
François Gessier, Robert Mah, Philipp Holzer, Therese-Marie Stachyra, Andrea Vaupel, Vito Guagnano, Emmanuelle Wirth, Patrick Chène, Pascal Furet, Joseph Schoepfer, Aude Izaac, Bahaa Salem, Stefan Stutz, Joerg Kallen, Keiichi Masuya, Achim Schlapbach, Suzanne Chau
Publikováno v:
ChemMedChem. 14(14)
Hdm2 (human MDM2, human double minute 2 homologue) counteracts p53 function by direct binding to p53 and by ubiquitin-dependent p53 protein degradation. Activation of p53 by inhibitors of the p53-Hdm2 interaction is being pursued as a therapeutic str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f06228760b95695741263802f16121
https://pubmed.ncbi.nlm.nih.gov/31066983
https://pubmed.ncbi.nlm.nih.gov/31066983
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
IL-17A and IL-17F are prominent members of the IL-17 family of cytokines that regulates both innate and adaptive immunity. IL-17A has been implicated in chronic inflammatory and autoimmune diseases, and anti-IL-17A antibodies have shown remarkable cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87fd91f08ef0b0c979f77bb2ff0650b2
https://doi.org/10.1038/s41598-017-08360-9
https://doi.org/10.1038/s41598-017-08360-9
Autor:
Aude Izaac, Stefan Stutz, Patrick Chène, Emmanuelle Wirth, Achim Schlapbach, Keiichi Masuya, François Gessier, Robert Mah, Bahaa Salem, Andrea Vaupel, Therese-Marie Stachyra, Philipp Holzer, Vito Guagnano, Joseph Schoepfer, Pascal Furet, Joerg Kallen, Suzanne Chau
Publikováno v:
ChemMedChem. 14:1304-1304
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efe94a39c43df4c5bdda9b5a4aab3872
https://doi.org/10.1002/cmdc.201900400
https://doi.org/10.1002/cmdc.201900400
Autor:
Jiri Kovarik, Onur Boyman, Thomas Calzascia, Andreas Katopodis, Janine Woytschak, Lukas Sommer, Catherine H. Régnier, Chao Zou, Daniel Zingg, Gerhard Zenke, Simone Popp, Barbara Brannetti, Emmanuelle Wirth, Natalia Arenas-Ramirez
Publikováno v:
Sci Transl Med
Science Translational Medicine
Science Translational Medicine
Interleukin-2 (IL-2) immunotherapy is an attractive approach in treating advanced cancer. However, by binding to its IL-2 receptor α (CD25) subunit, IL-2 exerts unwanted effects, including stimulation of immunosuppressive regulatory T cells (Tregs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368dced5e550799aa528deaf8ef3ead0