Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Emmanuelle Waeckel-Enée"'
Autor:
Shuaishuai Zhu, Emmanuelle Waeckel-Énée, Masaya Oshima, Anna Moser, Marie-Andrée Bessard, Abdelaziz Gdoura, Kevin Roger, Nina Mode, Joanna Lipecka, Ayse Yilmaz, Barbara Bertocci, Julien Diana, Benjamin Saintpierre, Ida Chiara Guerrera, Raphael Scharfmann, Stefania Francesconi, François-Xavier Mauvais, Peter van Endert
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109929- (2024)
Summary: Tuning of protein homeostasis through mobilization of the unfolded protein response (UPR) is key to the capacity of pancreatic beta cells to cope with variable demand for insulin. Here, we asked how insulin-degrading enzyme (IDE) affects bet
Externí odkaz:
https://doaj.org/article/ef74b2002b644e86886ed16b4a9bb5e4
Autor:
Ayse Yilmaz, Chiara Guerrera, Emmanuelle Waeckel-Énée, Joanna Lipecka, Barbara Bertocci, Peter van Endert
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 890 (2023)
Insulin-degrading enzyme (IDE) is a highly conserved metalloprotease that is mainly localized in the cytosol. Although IDE can degrade insulin and some other low molecular weight substrates efficiently, its ubiquitous expression suggests additional f
Externí odkaz:
https://doaj.org/article/efcd5ab347e24b2098cf151936445e13
Autor:
Marije Baas, Alix Besançon, Tania Goncalves, Fabrice Valette, Hideo Yagita, Birgit Sawitzki, Hans-Dieter Volk, Emmanuelle Waeckel-Enée, Benedita Rocha, Lucienne Chatenoud, Sylvaine You
Publikováno v:
eLife, Vol 5 (2016)
CD8+ T cell anergy is a critical mechanism of peripheral tolerance, poorly investigated in response to immunotherapy. Here, using a pancreatic islet allograft model and CD3 antibody therapy, we showed, by single cell gene profiling, that intragraft C
Externí odkaz:
https://doaj.org/article/7c54863af7d6404db93efed5b465bfb0
Autor:
Yamina Hamel, Benedita Rocha, François-Xavier Mauvais, Corinne Cordier, Émilie Barilleau, Jérôme Mégret, Hang-Phuong Pham, Christophe Marchi, Jacques Beltrand, Agnes Hartemann, Adrien Six, Roland Kratzer, Jean-Jacques Robert, Emmanuelle Waeckel-Enée, Peter van Endert, Jean-Baptiste Arnoux, Pascale de Lonlay
Publikováno v:
Journal of Autoimmunity. 73:54-63
Human type 1 diabetes results from a destructive auto-reactive immune response in which CD8(+) T lymphocytes play a critical role. Given the intense ongoing efforts to develop immune intervention to prevent and/or cure the disease, biomarkers suitabl
Autor:
Harry Sokol, Emmanuelle Waeckel-Enée, Michela Miani, Marjolène Straube, Peter van Endert, Julien Diana, Patrick Emond, Subash chand Verma, Bernhard Ryffel, Julie Le Naour
Publikováno v:
Cell Metabolism
Cell Metabolism, Elsevier, 2018, 28 (4), pp.557-572.e6. ⟨10.1016/j.cmet.2018.06.012⟩
Cell Metabolism, 2018, 28 (4), pp.557-572.e6. ⟨10.1016/j.cmet.2018.06.012⟩
Cell Metabolism, Elsevier, 2018, 28 (4), pp.557-572.e6. ⟨10.1016/j.cmet.2018.06.012⟩
Cell Metabolism, 2018, 28 (4), pp.557-572.e6. ⟨10.1016/j.cmet.2018.06.012⟩
International audience; The gut microbiota is essential for the normal function of the gut immune system and microbiota alterations are associated with autoimmune disorders. However, how the gut microbiota prevents autoimmunity in distant organs rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::188fc86ad65575b7b2a224d419974f36
https://hal.sorbonne-universite.fr/hal-01907399/file/DIANA_Julien.pdf
https://hal.sorbonne-universite.fr/hal-01907399/file/DIANA_Julien.pdf
Autor:
Benedita Rocha, Marije C. Baas, Tania Goncalves, Fabrice Valette, Sylvaine You, Emmanuelle Waeckel-Enée, Alix Besançon, Hideo Yagita, Lucienne Chatenoud, Birgit Sawitzki, Hans-Dieter Volk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01fd4c70296e50b6e9e4cbbccafb4af9
https://doi.org/10.7554/elife.08133.025
https://doi.org/10.7554/elife.08133.025