Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Emmanuelle S Jecrois"'
Autor:
Edward Kim, Yuan Wang, Sun-Jung Kim, Miriam Bornhorst, Emmanuelle S Jecrois, Todd E Anthony, Chenran Wang, Yi E Li, Jun-Lin Guan, Geoffrey G Murphy, Yuan Zhu
Publikováno v:
eLife, Vol 3 (2014)
Individuals with neurofibromatosis type 1 (NF1) frequently exhibit cognitive and motor impairments and characteristics of autism. The cerebellum plays a critical role in motor control, cognition, and social interaction, suggesting that cerebellar def
Externí odkaz:
https://doaj.org/article/69893e3789f342999cbbd8405c75c4f8
Publikováno v:
Molecular & Cellular Oncology, Vol 8, Iss 6 (2021)
Pediatric low-grade gliomas (pLGGs) are almost universally driven by abnormal activation of RAS-mediated MEK-ERK/MAPK signaling pathway. pLGGs predominantly occur in children, suggesting that they originate in an ERK-dependent neural stem/progenitor
Externí odkaz:
https://doaj.org/article/420554039c47499fbe46f89c916a56e8
Publikováno v:
Mol Cell Oncol
Pediatric low-grade gliomas (pLGGs) are almost universally driven by abnormal activation of RAS-mediated MEK-ERK/MAPK signaling pathway. pLGGs predominantly occur in children, suggesting that they originate in an ERK-dependent neural stem/progenitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a84361b26bc5321c747902032b7f533
https://pubmed.ncbi.nlm.nih.gov/35419473
https://pubmed.ncbi.nlm.nih.gov/35419473
Autor:
Shayne F. Andrew, Matthew K. Krause, Emmanuelle S. Jecrois, Austin Friend, Jingwen Jiang, Yinghua Li, Yuan Zhu, Daphine Muguyo, Francisco M Nadal-Nicolás, Brianna R. Pierce, Wei Li, Hongmei Mao, Sharon Huynh, Yuan Wang, Steven F Stasheff, Miriam Bornhorst, Roger J. Packer, Daniel M. Treisman, Hui Zong, Wang Zheng
Publikováno v:
Developmental cell. 56(20)
The mechanism of vulnerability to pediatric low-grade gliomas (pLGGs)-the most common brain tumor in children-during development remains largely unknown. Using mouse models of neurofibromatosis type 1 (NF1)-associated pLGGs in the optic pathway (NF1-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19bf0a68f78ffeeb46836bbdc994324
https://pubmed.ncbi.nlm.nih.gov/34699786
https://pubmed.ncbi.nlm.nih.gov/34699786
Autor:
Yaoyu E. Wang, Nan Ke, Richard C. Han, Roderick T. Bronson, Lijun Liu, Agnieszka Zagozdzon, Katharine E. Sweeney, Emmanuelle S. Jecrois, Piotr Sicinski, Wojciech Michowski, Ewa Sicinska, Joel M. Chick, Steven P. Gygi, Yan Geng
Publikováno v:
Proceedings of the National Academy of Sciences. 115:1015-1020
E-type cyclins (cyclins E1 and E2) are components of the core cell cycle machinery and are overexpressed in many human tumor types. E cyclins are thought to drive tumor cell proliferation by activating the cyclin-dependent kinase 2 (CDK2). The cyclin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135cab39d40ff1e4f3c61f588a434d5c
https://doi.org/10.1073/pnas.1711477115
https://doi.org/10.1073/pnas.1711477115
Autor:
Sheyla V. Candido, Richard C. Han, Kristin A. Mulry, Mary S. Pilarz, Emmanuelle S. Jecrois, Tobias Otto, Roderick T. Bronson, Michaela Bowden, Anne Fassl, Ewa Sicinska, Piotr Sicinski, Iga A. Lachowicz
Publikováno v:
Proceedings of the National Academy of Sciences. 114:10660-10665
MicroRNAs (miRNAs) have been known to affect various biological processes by repressing expression of specific genes. Here we describe an essential function of the miR-34/449 family during differentiation of epithelial cells. We found that miR-34/449
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c236cba795312168b70c8412ab37ba6
https://doi.org/10.1073/pnas.1702914114
https://doi.org/10.1073/pnas.1702914114
BACKGROUND: Up to 20% of patients with Neurofibromatosis 1 (NF1) are diagnosed with optic pathway gliomas (OPGs) before 7 years of age, suggesting these tumors are formed during development. Yet, the early events that occur in the optic nerve (ON), r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::207287444df078ca48b5af2a159ec2c7
https://europepmc.org/articles/PMC5474994/
https://europepmc.org/articles/PMC5474994/
Autor:
Jun-Lin Guan, Yuan Wang, Emmanuelle S. Jecrois, Yuan Zhu, Chenran Wang, Todd E. Anthony, Yi E. Li, Geoffrey G. Murphy, Sun-Jung Kim, Miriam Bornhorst, Edward Y. Kim
Publikováno v:
eLife
eLife, Vol 3 (2014)
eLife, Vol 3 (2014)
Individuals with neurofibromatosis type 1 (NF1) frequently exhibit cognitive and motor impairments and characteristics of autism. The cerebellum plays a critical role in motor control, cognition, and social interaction, suggesting that cerebellar def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79637315d7699507980b6029c0b924ef
https://doi.org/10.7554/elife.05151
https://doi.org/10.7554/elife.05151
Autor:
Edward Kim, Yuan Wang, Sun-Jung Kim, Miriam Bornhorst, Emmanuelle S Jecrois, Todd E Anthony, Chenran Wang, Yi E Li, Jun-Lin Guan, Geoffrey G Murphy, Yuan Zhu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d0cf6db9a5803e607d07896402b81a8
https://doi.org/10.7554/elife.05151.023
https://doi.org/10.7554/elife.05151.023