Α de novo 3.8-Mb inversion affecting the EDA and XIST genes in a heterozygous female calf with generalized hypohidrotic ectodermal dysplasia

Autor: Clémentine Escouflaire, Emmanuelle Rebours, Mathieu Charles, Sébastien Orellana, Margarita Cano, Julie Rivière, Cécile Grohs, Hélène Hayes, Aurélien Capitan

Publikováno v: BMC Genomics, Vol 20, Iss 1, Pp 1-11 (2019)

Abstract Background In mammals, hypohidrotic ectodermal dysplasia (HED) is a genetic disorder that is characterized by sparse hair, tooth abnormalities, and defects in cutaneous glands. Only four genes, EDA, EDAR, EDARADD and WNT10A account for more

Externí odkaz: https://doaj.org/article/8f27ea9365cd4d0c80e877f60afa6c7a

Identification of copy number variation in French dairy and beef breeds using next-generation sequencing

Autor: Rabia Letaief, Emmanuelle Rebours, Cécile Grohs, Cédric Meersseman, Sébastien Fritz, Lidwine Trouilh, Diane Esquerré, Johanna Barbieri, Christophe Klopp, Romain Philippe, Véronique Blanquet, Didier Boichard, Dominique Rocha, Mekki Boussaha

Publikováno v: Genetics Selection Evolution, Vol 49, Iss 1, Pp 1-15 (2017)

Abstract Background Copy number variations (CNV) are known to play a major role in genetic variability and disease pathogenesis in several species including cattle. In this study, we report the identification and characterization of CNV in eight Fren

Externí odkaz: https://doaj.org/article/9f283a0c299c433ebbe5fbe4244d3f77

Linkage disequilibrium and past effective population size in native Tunisian cattle

Autor: Mekki Boussaha, Slim Ben Jemaa, Emmanuelle Rebours, Sofiane Mnara, Nejia Thamri, Dominique Rocha

Publikováno v: Genetics and Molecular Biology
Genetics and Molecular Biology, Sociedade Brasileira de Genética, 2019, 42 (1), pp.52-61. ⟨10.1590/1678-4685-GMB-2017-0342⟩
Genetics and Molecular Biology, Vol 42, Iss 1, Pp 52-61 (2019)
Genetics and Molecular Biology v.42 n.1 2019
Sociedade Brasileira de Genética (SBG)
instacron:SBG
Genetics and Molecular Biology, Issue: ahead, Published: 18 FEB 2019
Genetics and Molecular Biology, Volume: 42, Issue: 1, Pages: 52-61, Published: 18 FEB 2019
Genetics and Molecular Biology 1 (42), 52-61. (2019)

International audience; To carry out effective genome-wide association studies, information about linkage disequilibrium (LD) is essential. Here, we used medium-density SNP chips to provide estimates of LD in native Tunisian cattle. The two measures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f712479db56908c4925574ab46ed3837
https://hal.inrae.fr/hal-02622927

Identification of copy number variation in French dairy and beef breeds using next-generation sequencing

Autor: Didier Boichard, Lidwine Trouilh, Diane Esquerre, Cécile Grohs, Mekki Boussaha, Johanna Barbieri, Sébastien Fritz, Véronique Blanquet, Rabia Letaief, Dominique Rocha, Romain Philippe, Emmanuelle Rebours, Cédric Meersseman, Christophe Klopp

Publikováno v: Genetics Selection Evolution 1 (49), 77. (2017)
Genetics Selection Evolution
Genetics Selection Evolution, BioMed Central, 2017, 49 (1), pp.77. ⟨10.1186/s12711-017-0352-z⟩
Genetics, Selection, Evolution : GSE
Genetics Selection Evolution, 2017, 49 (1), pp.77. ⟨10.1186/s12711-017-0352-z⟩
Genetics Selection Evolution, Vol 49, Iss 1, Pp 1-15 (2017)

Background : We report the identification and localization of 4178 putative deletion-only, duplication-only and CNV regions, which cover 6% of the bovine autosomal genome; they were validated by two in silico approaches and/or experimentally validate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e535cc0ed511a38cc90cc4dc04fcb81
http://prodinra.inra.fr/record/415377

Flt3 ligand improves the innate response to respiratory syncytial virus and limits lung disease upon RSV reexposure in neonate mice

Autor: Sabine Riffault, Luc Jouneau, Aude Remot, Jérôme Lecardonnel, Daphné Laubreton, Agnès Petit-Camurdan, Catherine Dubuquoy, Delphyne Descamps, Stephan Bouet, Emmanuelle Rebours

Publikováno v: European Journal of Immunology
European Journal of Immunology, Wiley-VCH Verlag, 2016, 46 (4), pp.874-884. ⟨10.1002/eji.201545929⟩

Respiratory syncytial virus (RSV) causes severe bronchiolitis in infants worldwide. The immunological factors responsible for RSV susceptibility in infants are poorly understood. Here, we used the BALB/c mouse model of neonatal RSV infection to study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d924d029b20a49e523529ca958e3b1b1
https://pubmed.ncbi.nlm.nih.gov/26681580