TIMP-1 binding to proMMP-9/CD44 complex localized at the cell surface promotes erythroid cell survival

Autor: Emmanuelle Petitfrère-Charpentier, William Hornebeck, Laurent Duca, Marie-Line Sowa, Emilie Dassé, Jérôme Devy, Elise Lambert, Laurent Martiny, Lucie Bridoux

Publikováno v: International Journal of Biochemistry and Cell Biology
International Journal of Biochemistry and Cell Biology, Elsevier, 2009, 41 (5), pp.1102-1115

Besides its ability to inhibit MMP activity, TIMP-1 exhibits other biological functions. We earlier reported that TIMP-1 induced UT-7 erythroid cell survival through activation of the JAK2/PI 3-kinase/Akt pathway and we now aim to determine whether t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393579f5fc54903929bfbc1ef94fe3c2
https://doi.org/10.1016/j.biocel.2008.10.017