Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Emmanuelle Martini"'
Autor:
Aloïse Mabondzo, Rania Harati, Léa Broca-Brisson, Anne-Cécile Guyot, Narciso Costa, Francesco Cacciante, Elena Putignano, Laura Baroncelli, Matthew R. Skelton, Cathy Saab, Emmanuelle Martini, Henri Benech, Thomas Joudinaud, Jean-Charles Gaillard, Jean Armengaud, Rifat Hamoudi
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Creatine transporter deficiency (CTD), a leading cause of intellectual disability is a result of the mutation in the gene encoding the creatine transporter SLC6A8, which prevents creatine uptake into the brain, causing mental retardation, expressive
Externí odkaz:
https://doaj.org/article/0bb10f0055e5490bb1303111e63f33c4
Autor:
Sandrine Caburet, Anne-Laure Todeschini, Cynthia Petrillo, Emmanuelle Martini, Nada D. Farran, Bérangère Legois, Gabriel Livera, Johnny S. Younis, Stavit Shalev, Reiner A. Veitia
Publikováno v:
EBioMedicine, Vol 42, Iss , Pp 524-531 (2019)
Background: Primary Ovarian Insufficiency (POI), a major cause of infertility, affects about 1–3% of women under forty years of age. Although there is a growing list of causal genetic alterations, POI remains mostly idiopathic. Methods: We performe
Externí odkaz:
https://doaj.org/article/c89c6aa10eb94c78b3262f14448ee5de
Publikováno v:
Cancers, Vol 13, Iss 9, p 2083 (2021)
Homologous recombination (HR) is a fundamental evolutionarily conserved process that plays prime role(s) in genome stability maintenance through DNA repair and through the protection and resumption of arrested replication forks. Many HR genes are der
Externí odkaz:
https://doaj.org/article/0c29a01e9553433992f008e6bd953595
Autor:
Emilie Abby, Sophie Tourpin, Jonathan Ribeiro, Katrin Daniel, Sébastien Messiaen, Delphine Moison, Justine Guerquin, Jean-Charles Gaillard, Jean Armengaud, Francina Langa, Attila Toth, Emmanuelle Martini, Gabriel Livera
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Meiosis is a cell division program that produces haploid gametes and is initiated by a retinoic acid-dependent process. Here the authors report that a meiosis-specific protein, MEIOC, is upregulated in a retinoic acid-independent manner and is requir
Externí odkaz:
https://doaj.org/article/bde576af3dd940e5a1614982a6048f7f
Autor:
Benoit Souquet, Emilie Abby, Roxane Hervé, Friederike Finsterbusch, Sophie Tourpin, Ronan Le Bouffant, Clotilde Duquenne, Sébastien Messiaen, Emmanuelle Martini, Jacqueline Bernardino-Sgherri, Attila Toth, René Habert, Gabriel Livera
Publikováno v:
PLoS Genetics, Vol 9, Iss 9, p e1003784 (2013)
Meiotic recombination is a mandatory process for sexual reproduction. We identified a protein specifically implicated in meiotic homologous recombination that we named: meiosis specific with OB domain (MEIOB). This protein is conserved among metazoan
Externí odkaz:
https://doaj.org/article/2f8937b06c40480ba400755bdd38570d
Autor:
Emmanuelle Martini, Valérie Borde, Matthieu Legendre, Stéphane Audic, Béatrice Regnault, Guillaume Soubigou, Bernard Dujon, Bertrand Llorente
Publikováno v:
PLoS Genetics, Vol 7, Iss 9, p e1002305 (2011)
Meiotic DNA double-strand breaks (DSBs) initiate crossover (CO) recombination, which is necessary for accurate chromosome segregation, but DSBs may also repair as non-crossovers (NCOs). Multiple recombination pathways with specific intermediates are
Externí odkaz:
https://doaj.org/article/055a1411cf3b471c9ee7911da726fd25
Autor:
Sébastien Messiaen, Delphine Moison, Claire Torres, Daniel Lewandowski, Gabriel Livera, Vincent Puy, Emmanuelle Martini, Véronique Ménard, Nelly Frydman, Caroline Devanand, Vilma Barroca, Marie-Justine Guerquin
Publikováno v:
Reproductive BioMedicine Online. 43:799-809
Research question What is the impact of radiation exposure on oocyte quality and female fertility? Design Prepubertal mice underwent whole-body irradiation with a single dose (0.02, 0.1, 0.5, 2, 8 Gy) of gamma- or X-rays. Oocytes were quantified in i
Autor:
Gabriel Matos-Rodrigues, Vilma Barroca, Ali-Akbar Muhammad, Awatef Allouch, Stephane Koundrioukoff, Daniel Lewandowski, Emmanuelle Despras, Josée Guirouilh-Barbat, Lucien Frappart, Patricia Kannouche, Pauline Dupaigne, Eric Le Cam, Jean-Luc Perfettini, Paul-Henri Romeo, Michelle Debatisse, Maria Jasin, Gabriel Livera, Emmanuelle Martini, Bernard S. Lopez
Genetic instability is a hallmark of both cancer and aging. Homologous recombination (HR) is a prominent DNA repair pathway maintaining genomic integrity. Mutations in many HR genes lead to cancer predisposition. Paradoxically, the consequences of mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec47a23db0da61623d6b36d46f25491d
https://hal.science/hal-03860785
https://hal.science/hal-03860785
Autor:
Aloïse Mabondzo, Rania Harati, Léa Broca-Brisson, Anne-Cécile Guyot, Narciso Costa, Francesco Cacciante, Elena Putignano, Laura Baroncelli, Matthew R Skelton, Cathy Saab, Emmanuelle Martini, Henri Benech, Thomas Joudinaud, Jean-Charles Gaillard, Jean Armengaud, Rifat A. Hamoudi
Creatine transporter deficiency prevents creatine uptake into the brain, leading to mental retardation. To better understand the pathophysiology, this study focuses on the identification of biomarkers related to cognitive improvement in a Slc6a8 knoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43a63dca6b66122fa4139e1ad3f34015
https://doi.org/10.1101/2022.11.03.514982
https://doi.org/10.1101/2022.11.03.514982
Autor:
Sonia Abdallah, Amandine Jampy, Delphine Moison, Margaux Wieckowski, Sébastien Messiaen, Emmanuelle Martini, Anna Campalans, Juan Pablo Radicella, Virginie Rouiller-Fabre, Gabriel Livera, Marie-Justine Guerquin
Publikováno v:
Environmental Pollution
Environmental Pollution, 2023, 317, pp.120791. ⟨10.1016/j.envpol.2022.120791⟩
Environmental Pollution, 2023, 317, pp.120791. ⟨10.1016/j.envpol.2022.120791⟩
International audience; Many endocrine disruptors have been proven to impair the meiotic process which is required for the production of healthy gametes. Bisphenol A is emblematic of such disruptors, as it impairs meiotic prophase I and causes oocyte