Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Emmanuelle J Meuillet"'
Autor:
Lu Chen, Lei Du-Cuny, Sylvestor Moses, Sabrina Dumas, Zuohe Song, Abdol Hossein Rezaeian, Hui-Kuan Lin, Emmanuelle J Meuillet, Shuxing Zhang
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 1, p e1004021 (2015)
The Grb2-associated binding protein 1 (GAB1) integrates signals from different signaling pathways and is over-expressed in many cancers, therefore representing a new therapeutic target. In the present study, we aim to target the pleckstrin homology (
Externí odkaz:
https://doaj.org/article/56c804a6540e4387827ecf871d75e93e
Publikováno v:
Bioengineering & Translational Medicine, Vol 6, Iss 1, Pp n/a-n/a (2021)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is often associated with a poor prognosis due to silent onset, resistance to therapies, and rapid spreading. Most patients are ineligible for curable surgery as they present with advanced disease at th
Externí odkaz:
https://doaj.org/article/ac9113733dd34736a28773ad01acaa7f
Autor:
Garth Powis, Lynn Kirkpatrick, Robert C. Liddington, Laurie A. Bankston, Ricardo G. Correa, Fabiana I.A.L. Layng, Lei Du-Cuny, Robert Lemos, Shuxing Zhang, Emmanuelle J. Meuillet, Zamal Ahmed, Michael Scott, Geoffrey Grandjean, Nathan T. Ihle, Marco Maruggi, Roisin Puentes, Martin Indarte
An inhibitor of the pleckstrin homology domain of CNK1 selectively blocks the growth of mutant KRAS cells and tumors Supplemental Information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4049decc5165ea5a5548638457e6315
https://doi.org/10.1158/0008-5472.22421073
https://doi.org/10.1158/0008-5472.22421073
Autor:
Garth Powis, Lynn Kirkpatrick, Robert C. Liddington, Laurie A. Bankston, Ricardo G. Correa, Fabiana I.A.L. Layng, Lei Du-Cuny, Robert Lemos, Shuxing Zhang, Emmanuelle J. Meuillet, Zamal Ahmed, Michael Scott, Geoffrey Grandjean, Nathan T. Ihle, Marco Maruggi, Roisin Puentes, Martin Indarte
Cnk1 (connector enhancer of kinase suppressor of Ras 1) is a pleckstrin homology (PH) domain–containing scaffold protein that increases the efficiency of Ras signaling pathways, imparting efficiency and specificity to the response of cell prolifera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::570ccd2ee8215290557b6c0ec2d39371
https://doi.org/10.1158/0008-5472.c.6510828.v1
https://doi.org/10.1158/0008-5472.c.6510828.v1
Autor:
Emmanuelle J. Meuillet, Garth Powis, Eugene A. Mash, Shuxing Zhang, A. Geoffrey Skillman, Nathan Ihle, Robert Lemos, Li Li Zhou, Lei Du-Cuny, Song Zuohe, M. Ahad Ali, Sylvestor A. Moses
Supplementary Tables 1-2, Appendix materials, Figures 1-2 from In vitro and In vivo Activity of Novel Small-Molecule Inhibitors Targeting the Pleckstrin Homology Domain of Protein Kinase B/AKT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14018e0cbb010bd7fb1585a03f6da112
https://doi.org/10.1158/0008-5472.22378998.v1
https://doi.org/10.1158/0008-5472.22378998.v1
Autor:
Soheb Anwar Mohammed, Muhammad Wahab Amjad, Xucai Chen, Maria F. Acosta, Dillion Hanrahan, Emmanuelle J. Meuillet, Evan C. Unger, John J. Pacella
Publikováno v:
The Journal of the Acoustical Society of America. 153:A141-A141
More than 1 million Americans yearly have a new or recurrent acute myocardial infarction (AMI). Although the mortality rate from AMI has decreased in recent years, post-MI congestive heart failure is increasing due to microvascular obstruction (MVO),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a8e386112fc23c2580c7936f68476ed
https://doi.org/10.1121/10.0018436
https://doi.org/10.1121/10.0018436
Autor:
Soheb Anwar Mohammed, Xucai Chen, Maria Fernanda F Acosta, Dillon Hanrahan, Evan C Unger, Emmanuelle J MEUILLET, John Pacella
Publikováno v:
Circulation. 144
Introduction: Microvascular obstruction (MVO) following coronary intervention is a common problem associated with worse clinical outcome, and has no consistent therapy. We are developing a new technique termed sonoreperfusion (SRP), to restore microv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::431ac25cb860f9f8144f3396c68fe7e1
https://doi.org/10.1161/circ.144.suppl_1.14089
https://doi.org/10.1161/circ.144.suppl_1.14089
Autor:
Richard B. S. Roden, Altaf Mohammed, Mark Steven Miller, Robert J. Glynn, Ming You, Zelton D Sharp, Roderick H. Dashwood, Haval Shirwan, Susan R. Mallery, Steven M. Lipkin, Eduardo Vilar, Shadmehr Demehri, Powel H. Brown, Seema A. Khan, Chinthalapally V. Rao, Bryon D. Johnson, Mary L. Disis, Eva Szabo, Peter J. Allen, Raymond N. DuBois, Jill M. Siegfried, Thomas W. Kensler, Karen T. Liby, Andrew T. Chan, Emmanuelle J. Meuillet, Margie L. Clapper, Robert E. Schoen
Publikováno v:
Journal of Cancer Prevention
The Division of Cancer Prevention of the National Cancer Institute (NCI) and the Office of Disease Prevention of the National Institutes of Health co-sponsored the Translational Advances in Cancer Prevention Agent Development Meeting on August 27 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60b66cfce6425cec2d983eaaf20c4456
https://pubmed.ncbi.nlm.nih.gov/33842408
https://pubmed.ncbi.nlm.nih.gov/33842408
Autor:
Iman Daryaei, Emmanuelle J. Meuillet, Rakesh Bam, Sanjiv S. Gambhir, Evan C. Unger, Jose G. Vilches-Moure, Amelie M. Lutz, Edmund R. Marinelli, Lotfi Abou-Elkacem, Ramasamy Paulmurugan
Publikováno v:
Invest Radiol
OBJECTIVES: Early detection of Pancreatic Ductal Adenocarcinoma (PDAC) represents the most significant step towards the treatment of this aggressive lethal disease. Previously, we engineered a pre-clinical Thy1-targeted microbubble (MB(Thy1)) contras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6e02d312ca77bdf86c71410ba355c6
https://pubmed.ncbi.nlm.nih.gov/32569010
https://pubmed.ncbi.nlm.nih.gov/32569010