Initiation of cyp26a1 Expression in the Zebrafish Anterior Neural Plate by a Novel Cis-Acting Element.

Autor: Chunhong Chen, Aline Stedman, Emmanuelle Havis, Isabelle Anselme, Daria Onichtchouk, François Giudicelli, Sylvie Schneider-Maunoury

Publikováno v: PLoS ONE, Vol 11, Iss 3, p e0150639 (2016)

Early patterning of the vertebrate neural plate involves a complex hierarchy of inductive interactions orchestrated by signalling molecules and their antagonists. The morphogen retinoic acid, together with the Cyp26 enzymes which degrade it, play a c

Externí odkaz: https://doaj.org/article/608d45c711654948a9178d95df2032be

ISL1 directly regulates FGF10 transcription during human cardiac outflow formation.

Autor: Christelle Golzio, Emmanuelle Havis, Philippe Daubas, Gregory Nuel, Candice Babarit, Arnold Munnich, Michel Vekemans, Stéphane Zaffran, Stanislas Lyonnet, Heather C Etchevers

Publikováno v: PLoS ONE, Vol 7, Iss 1, p e30677 (2012)

The LIM homeodomain gene Islet-1 (ISL1) encodes a transcription factor that has been associated with the multipotency of human cardiac progenitors, and in mice enables the correct deployment of second heart field (SHF) cells to become the myocardium

Externí odkaz: https://doaj.org/article/5b843ab15271402781cb5edc27449063

NOTCH inhibition promotes myoblast fusion by releasing HEYL repression on TMEM8C regulatory regions in foetal skeletal muscles

Autor: Marie-Ange Bonnin, Estelle Hirsinger, Cédrine Blavet, Delphine Duprez, Emmanuelle Havis, Joana Esteves de Lima

Differentiation and fusion are two intricate processes involved in skeletal muscle development. The close association of differentiation and fusion makes it difficult to address the process of fusion independently of differentiation. Using the fusion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de28af0ab271eb495e86f32de9d647a
https://hal.archives-ouvertes.fr/hal-03002440

EGR1 Transcription Factor is a Multifaceted Regulator of Matrix Production in Tendons and Other Connective Tissues

Autor: Delphine Duprez, Emmanuelle Havis

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2020, 21, ⟨10.3390/ijms21051664⟩
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1664 (2020)

Although the transcription factor EGR1 is known as NGF1-A, TIS8, Krox24, zif/268, and ZENK, it still has many fewer names than biological functions. A broad range of signals induce Egr1 gene expression via numerous regulatory elements identified in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae4560a68c132db4932f8e87b16fe92
https://pubmed.ncbi.nlm.nih.gov/32121305

Delivery of adipose‐derived stem cells in poloxamer hydrogel improves peripheral nerve regeneration

Autor: Damian Grybowski, J. Peter Rubin, Wesley N. Sivak, Kacey G. Marra, Emmanuelle Havis, Deok‐Yeol Kim, Isaac B. James, Matthias Waldner, Gabriella DiBernardo, Kassandra Allbright, Jacqueline M. Bliley

Publikováno v: Muscle & Nerve. 58:251-260

Introduction Peripheral nerve damage is associated with high long-term morbidity. Because of beneficial secretome, immunomodulatory effects, and ease of clinical translation, transplantation with adipose-derived stem cells (ASC) represents a promisin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de1499e38622fc6665dc33a5e457ca4
https://doi.org/10.1002/mus.26094