Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Emmanuelle Fabre"'
Autor:
Sarah Tessier, Omar Ferhi, Marie-Claude Geoffroy, Román González-Prieto, Antoine Canat, Samuel Quentin, Marika Pla, Michiko Niwa-Kawakita, Pierre Bercier, Domitille Rérolle, Pierre Therizols, Emmanuelle Fabre, Alfred C. O. Vertegaal, Hugues de Thé, Valérie Lallemand-Breitenbach
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Here the authors identify novel PML-partners and demonstrate that PML NBs control their sumoylation and that PML-controlled sumoylation of transcriptional regulators maintains the embryonic stem cell transcriptome and transposable element silencing.
Externí odkaz:
https://doaj.org/article/5fa232a562fb4fdfab6f62d5a90021c8
Autor:
Fabiola García Fernández, Etienne Almayrac, Ànnia Carré Simon, Renaud Batrin, Yasmine Khalil, Michel Boissac, Emmanuelle Fabre
Publikováno v:
eLife, Vol 11 (2022)
Repair of DNA double-strand breaks (DSBs) is crucial for genome integrity. A conserved response to DSBs is an increase in chromatin mobility that can be local, at the site of the DSB, or global, at undamaged regions of the genome. Here, we address th
Externí odkaz:
https://doaj.org/article/ef6ed1502f5145a2ac52d994374dca0f
Autor:
Pascal Wang, Emmanuelle Fabre, Antoine Martin, Kader Chouahnia, Ambre Benabadji, Lise Matton, Boris Duchemann
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundNew mutational detection techniques like next-generation sequencing have resulted in an increased number of cases with uncommon mutation and compound mutations [3%–14% of all epidermal growth factor receptor (EGFR) mutations]. In rare exo
Externí odkaz:
https://doaj.org/article/3581a5abb8ee400bbf490cc96629ef2f
Autor:
Christopher Bruhn, Arta Ajazi, Elisa Ferrari, Michael Charles Lanz, Renaud Batrin, Ramveer Choudhary, Adhish Walvekar, Sunil Laxman, Maria Pia Longhese, Emmanuelle Fabre, Marcus Bustamente Smolka, Marco Foiani
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The relationship between DNA damage response (DDR) and regulation of the tolerance to glucose restriction is currently unclear. Here the authors reveal that maintaining a physiological level of histones by Rad53-Spt21 is necessary for glucose toleran
Externí odkaz:
https://doaj.org/article/c1334c64c88341dd9b8f7f4e9f177694
Autor:
Sarah Tessier, Omar Ferhi, Marie-Claude Geoffroy, Román González-Prieto, Antoine Canat, Samuel Quentin, Marika Pla, Michiko Niwa-Kawakita, Pierre Bercier, Domitille Rérolle, Marilyn Tirard, Pierre Therizols, Emmanuelle Fabre, Alfred C. O. Vertegaal, Hugues de Thé, Valérie Lallemand-Breitenbach
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/43bf9cc247ef4f48ab070961d4555b8d
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-15 (2017)
Abstract Background The structure and mechanical properties of chromatin impact DNA functions and nuclear architecture but remain poorly understood. In budding yeast, a simple polymer model with minimal sequence-specific constraints and a small numbe
Externí odkaz:
https://doaj.org/article/f7357732354b4a909d56de214e3bb49f
Autor:
Maya Spichal, Emmanuelle Fabre
Publikováno v:
Frontiers in Genetics, Vol 8 (2017)
Chromosomes underlie a dynamic organization that fulfills functional roles in processes like transcription, DNA repair, nuclear envelope stability, and cell division. Chromosome dynamics depend on chromosome structure and cannot freely diffuse. Furth
Externí odkaz:
https://doaj.org/article/090273c09e2c4afd91a607e2a284f4b7
Publikováno v:
Cells, Vol 8, Iss 6, p 582 (2019)
Cellular memory is a critical ability that allows microorganisms to adapt to potentially detrimental environmental fluctuations. In the unicellular eukaryote Saccharomyces cerevisiae, cellular memory can take the form of faster or slower responses wi
Externí odkaz:
https://doaj.org/article/ca015c9b117c4635bc0a5fd86fc0adbd
Autor:
Elhadji Mamadou Moussa Thioye, Eric Vicaut, Etienne Larger, Meriem Sal, Sara Pinto, Narimane Berkane, Emmanuelle Fabre, Yoann Lalatonne, Angela Sutton, Charlotte Nachtergaele, Jean-Jacques Portal, Lionel Carbillon, Hélène Bihan, Emmanuel Cosson
Publikováno v:
Diabetes Care.
Autor:
Emmanuelle FABRE, Ànnia Carré Simon
Publikováno v:
Genes, Vol 13, Iss 7, p 7 (2022)
Genes
Genes, 2022, 13 (1), pp.7. ⟨10.3390/genes13010007⟩
Genes
Genes, 2022, 13 (1), pp.7. ⟨10.3390/genes13010007⟩
International audience; The inability to repair damaged DNA severely compromises the integrity of any organism. In eukaryotes, the DNA damage response (DDR) operates within chromatin, a tightly organized DNA–histone complex in a non-random manner w