Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Emmanuelle, Ruiz"'
Autor:
Harrison M. Penrose, Rida Iftikhar, Morgan E. Collins, Eman Toraih, Emmanuelle Ruiz, Nathan Ungerleider, Hani Nakhoul, Erik F. Flemington, Emad Kandil, Shamita B. Shah, Suzana D. Savkovic
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The heterogeneous pathobiology underlying Ulcerative Colitis (UC) is not fully understood. Using publicly available transcriptomes from adult UC patients, we identified the immune cell landscape, molecular pathways, and differentially expres
Externí odkaz:
https://doaj.org/article/e760a94f0fe148a6a82d2a1f02490469
Autor:
Emmanuelle Ruiz, Harrison M. Penrose, Sandra Heller, Hani Nakhoul, Melody Baddoo, Erik F. Flemington, Emad Kandil, Suzana D. Savkovic
Publikováno v:
Gut Microbes, Vol 11, Iss 3, Pp 350-363 (2020)
Inflammatory bowel disease (IBD) has been linked to active signaling with bacterial components and reduced mitochondrial ATP production; however, synergism between both of these disease characteristics remains unclear. We aimed to determine in human
Externí odkaz:
https://doaj.org/article/15355e26874241f1bf6b0de62ccbd1f3
Autor:
Rida Iftikhar, Harrison M. Penrose, Angelle N. King, Yunah Kim, Emmanuelle Ruiz, Emad Kandil, Heather L. Machado, Suzana D. Savkovic
Publikováno v:
Metabolites, Vol 12, Iss 3, p 250 (2022)
Obesity, characterized by augmented inflammation and tumorigenesis, is linked to genetic predispositions, such as FOXO3 polymorphisms. As obesity is associated with aberrant macrophages infiltrating different tissues, including the colon, we aimed to
Externí odkaz:
https://doaj.org/article/8360caa076894cf0a3351031caf80f12
Autor:
Eman A Toraih, Emmanuelle Ruiz, Bo Ning, Giovane G Tortelote, Sylvia Hilliard, Krzysztof Moroz, Tony Hu, Manal S Fawzy, Emad Kandil
Publikováno v:
Journal of the American College of Surgeons. 236:732-750
Autor:
Mourad, Zerfaoui, Koji, Tsumagari, Eman, Toraih, Youssef, Errami, Emmanuelle, Ruiz, Mohammed Sohail M, Elaasar, Moroz, Krzysztof, Andrew B, Sholl, Sameh, Magdeldin, Mohamed, Soudy, Zakaria Y, Abd Elmageed, A Hamid, Boulares, Emad, Kandil
Publikováno v:
Am J Cancer Res
The presence of mutant BRAF (V600E) correlates with the risk of recurrence in papillary thyroid cancer (PTC) patients. However, not all PTC patients with BRAF (V600E) are associated with poor prognosis. Thus, understanding the mechanisms by which cer
Autor:
Emmanuelle Ruiz, Tianhua Niu, Paul Friedlander, Asim B. Abdel-Mageed, Muthusamy Kunnimalaiyaan, Mourad Zerfaoui, Emad Kandil
Publikováno v:
Surgery. 167:73-79
Although well-differentiated papillary thyroid cancer may remain indolent, lymph node metastases and the recurrence rates are approximately 50% and 20%, respectively. No current biomarkers are able to predict metastatic lymphadenopathy and recurrence
Autor:
Mourad Zerfaoui, Eman Toraih, Emmanuelle Ruiz, Youssef Errami, Abdallah S. Attia, Moroz Krzysztof, Zakaria Y. Abd Elmageed, Emad Kandil
Publikováno v:
Cancers; Volume 14; Issue 2; Pages: 311
Cancers, Vol 14, Iss 311, p 311 (2022)
Cancers, Vol 14, Iss 311, p 311 (2022)
Background: Previously, we have demonstrated that nuclear BRAFV600E is associated with melanoma aggressiveness and vemurafenib resistance. However, the underlying mechanisms of how nuclear localization of BRAFV600E promotes cell aggressiveness have n
Autor:
Rida Iftikhar, Patricia Snarski, Angelle N. King, Jenisha Ghimire, Emmanuelle Ruiz, Frank Lau, Suzana D. Savkovic
Publikováno v:
Cancers. 15:977
The obesity epidemic is associated with increased colorectal cancer (CRC) risk and progression, the mechanisms of which remain unclear. In obese individuals, hypertrophic epiploic adipose tissue (EPAT), attached to the colon, has unique characteristi
Autor:
Mourad Zerfaoui, Zakaria Y. Abd Elmageed, Youssef Errami, Eman Toraih, Solomon Alhassan, Emad Kandil, Emmanuelle Ruiz
Publikováno v:
Aging and disease. 14:992
Autor:
Mourad, Zerfaoui, Eman, Toraih, Emmanuelle, Ruiz, Youssef, Errami, Abdallah S, Attia, Moroz, Krzysztof, Zakaria Y, Abd Elmageed, Emad, Kandil
Publikováno v:
Cancers
Simple Summary Despite some successes of selective anti-BRAFV600E inhibitors, resistance remains a major challenge. The aim of our study is to determine the role of nuclear BRAFV600E and its newly identified partner, HMOX1, in melanoma aggressiveness