Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Emmanuel Wemakor"'
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207911 (2018)
Substandard and falsified medicines represent a serious threat for public health and patient safety. Especially in low and middle-income countries, the prevalence of substandard and falsified medicines is reportedly high. However, reliable informatio
Externí odkaz:
https://doaj.org/article/514235cb0f6a4df281aebe91ae8285f1
Autor:
Tambo Cletus, Edward Ngah Ndze, Simon Schäfermann, Dorothee Wistuba, Fidelis Nyaah, Lutz Heide, Georges Mutombo, Cathrin Hauk, Richard Neci, Harald Gross, Irina Helmle, Manyi Pattinora, Christine Häfele-Abah, Emmanuel Wemakor
Publikováno v:
The American Journal of Tropical Medicine and Hygiene
Falsified and substandard medicines may undermine the progress toward the Sustainable Development Goals. The present study investigated the quality of 13 essential medicines in Cameroon and the Democratic Republic of Congo (DR Congo). Five hundred si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3e40f899d205b4c7a801b995a1119a9
https://pubmed.ncbi.nlm.nih.gov/32394884
https://pubmed.ncbi.nlm.nih.gov/32394884
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0207911 (2018)
PLoS ONE, Vol 13, Iss 11, p e0207911 (2018)
Substandard and falsified medicines represent a serious threat for public health and patient safety. Especially in low and middle-income countries, the prevalence of substandard and falsified medicines is reportedly high. However, reliable informatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::92be0e4443d8622f92a339a8bb40b05f
https://pubmed.ncbi.nlm.nih.gov/30496234
https://pubmed.ncbi.nlm.nih.gov/30496234
Autor:
Bernd Kammerer, Lutz Heide, Bertolt Gust, Leonard Kaysser, Emmanuel Wemakor, Stefanie Siebenberg
Publikováno v:
Rapid Communications in Mass Spectrometry. 25:495-502
The development of reliable analytic methods, capable of separating mixtures of secondary metabolites as well as providing structural information, is essential for the investigation of secondary metabolites, e.g. from Streptomyces. Here we report a l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d5865cfa97d4164b227becc6fd9a4db
https://doi.org/10.1002/rcm.4889
https://doi.org/10.1002/rcm.4889
Autor:
Xiaoyu Tang, Bertolt Gust, Katharina Sedding, Emmanuel Wemakor, Stefanie Siebenberg, Susanne Hennig, Leonard Kaysser
Publikováno v:
ChemBioChem. 12:477-487
Napsamycins are potent inhibitors of bacterial translocase I, an essential enzyme in peptidoglycan biosynthesis, and are classified as uridylpeptide antibiotics. They comprise an N-methyl diaminobutyric acid, an ureido group, a methionine and two non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56b3f01af8fe450864d1fa0fd0d4f59
https://doi.org/10.1002/cbic.201000460
https://doi.org/10.1002/cbic.201000460
Autor:
Bernd Kammerer, Leonard Kaysser, Stefanie Siebenberg, Emmanuel Wemakor, Liane Lutsch, Bertolt Gust
Publikováno v:
Journal of Biological Chemistry. 284:14987-14996
Caprazamycins are potent anti-mycobacterial liponucleoside antibiotics isolated from Streptomyces sp. MK730-62F2 and belong to the translocase I inhibitor family. Their complex structure is derived from 5′-(β-O-aminoribosyl)-glycyluridine and comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05d8fd014fc6f2f8dc6e6d6db8c375b
https://doi.org/10.1074/jbc.m901258200
https://doi.org/10.1074/jbc.m901258200
Publikováno v:
ChemBioChem. 6:2316-2325
Clorobiocin is an aminocoumarin antibiotic containing a pyrrole-2-carboxyl moiety, attached through an ester bond to a deoxysugar. The pyrrole moiety is important for the binding of the antibiotic to its biological target, gyrase. The complete biosyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f772eeed185ba6698e2a4b5ace49526c
https://doi.org/10.1002/cbic.200500252
https://doi.org/10.1002/cbic.200500252
Publikováno v:
Plant and Cell Physiology. 38:844-850
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::122d1b5a3d35f39d2e9007786017f89f
https://doi.org/10.1093/oxfordjournals.pcp.a029243
https://doi.org/10.1093/oxfordjournals.pcp.a029243
Autor:
Stefanie, Siebenberg, Leonard, Kaysser, Emmanuel, Wemakor, Lutz, Heide, Bertolt, Gust, Bernd, Kammerer
Publikováno v:
Rapid communications in mass spectrometry : RCM. 25(4)
The development of reliable analytic methods, capable of separating mixtures of secondary metabolites as well as providing structural information, is essential for the investigation of secondary metabolites, e.g. from Streptomyces. Here we report a l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::735c1c01e2556bfa7530fc442c91f2d9
https://pubmed.ncbi.nlm.nih.gov/21259358
https://pubmed.ncbi.nlm.nih.gov/21259358
Autor:
Bernd Kammerer, Stefanie Siebenberg, Emmanuel Wemakor, José A. Salas, Leonard Kaysser, Bertolt Gust, Jae Kyung Sohng
Publikováno v:
Applied and environmental microbiology. 76(12)
Caprazamycins are potent antimycobacterials isolated from Streptomyces sp. MK730F-62F2 (23). In a pulmonary tuberculosis mouse model, they showed a therapeutic effect but no significant toxicity (24). The caprazamycins are assigned to the translocase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de724d67e66c466e8a97ec6974ec1a9f
https://pubmed.ncbi.nlm.nih.gov/20418426
https://pubmed.ncbi.nlm.nih.gov/20418426