Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Emmanuel U Okoro"'
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162561 (2016)
UNLABELLED:We previously reported that overexpression of catalase upregulated xenobiotic- metabolizing enzyme (XME) expression and diminished benzo(a)pyrene (BaP) intermediate accumulation in mouse aortic endothelial cells (MAECs). Endoplasmic reticu
Externí odkaz:
https://doaj.org/article/27cd0f4525c44b1183e1a1f505ed6997
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136895 (2015)
Activation of apolipoprotein E receptor-2 (apoER2) and very low density lipoprotein receptor (VLDLR) inhibits foam cell formation. Reelin is a ligand of these receptors. Here we generated two reelin subregions containing the receptor binding domain w
Externí odkaz:
https://doaj.org/article/346c23efddbf463ab9ceb602a3989f75
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51011 (2012)
Cholecystokinin (CCK) is a peptide hormone that induces bile release into the intestinal lumen which in turn aids in fat digestion and absorption in the intestine. While excretion of bile acids and cholesterol into the feces eliminates cholesterol fr
Externí odkaz:
https://doaj.org/article/1d5bd01548614c03968f6dfb421b0b35
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21453 (2011)
Despite the well known importance of apolipoprotein (Apo) E in cholesterol efflux, the effect of ApoE on the expression of ATP-binding cassette transporter A1 (ABCA1) has never been investigated. The objective of this study was to determine the effec
Externí odkaz:
https://doaj.org/article/a80c02f513cb403782f13ddcd0ae92df
Autor:
Emmanuel U. Okoro
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 12
International Journal of Molecular Sciences, Vol 22, Iss 6236, p 6236 (2021)
Volume 22
Issue 12
International Journal of Molecular Sciences, Vol 22, Iss 6236, p 6236 (2021)
Background Excess lipid droplets are frequently observed in arterial endothelial cells at sites of advanced atherosclerotic plaques. The mechanism or implication of this observation is unknown. Methods The role of tumor necrosis factor alpha (TNFɑ)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892e20be11fa70153a1b1bd80eeedbfe
https://doi.org/10.21203/rs.3.rs-267515/v1
https://doi.org/10.21203/rs.3.rs-267515/v1
Autor:
Cherae M. Farmer-Dixon, Emmanuel U. Okoro, Michael J Gipson, Chethan Sampath, Sasanka S. Chukkapalli, Pandu R. Gangula
Publikováno v:
J Periodontol
BACKGROUND: Periodontal disease (PD) is known to be associated with endothelial dysfunction in patients with coronary artery and/or cardiovascular disease. In our study, we sought to explore the virulence of P. gingivalis (Pg) affecting glycogen synt
Publikováno v:
The FASEB Journal. 33
Publikováno v:
International Journal of Molecular Sciences
Volume 19
Issue 11
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3593 (2018)
Volume 19
Issue 11
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3593 (2018)
Passage of apolipoprotein B-containing lipoproteins (apoB-LPs), i.e., triglyceride-rich lipoproteins (TRLs), intermediate-density lipoproteins (IDLs), and low-density lipoproteins (LDLs), through the endothelial monolayer occurs in normal and atheros
Publikováno v:
Biochemical and Biophysical Research Communications. 477:123-128
We previously reported that apolipoprotein E (apoE) upregulates ATP-binding cassette transporter A1 (ABCA1) transcription through phosphatidylinositol 3-kinase (PI3K). Here we demonstrate that treatment of murine macrophages with human apoE3 enhanced
Autor:
ZhongMao Guo, Evangeline Motley-Johnson, Hong Yang, ZhiJan Cao, Emmanuel U. Okoro, LiXia Miao
Publikováno v:
Biochemical and Biophysical Research Communications. 465:256-261
Accumulation of unesterified cholesterol-rich lipid vesicles in the subendothelial space contributes to atherogenesis. Transport of cholesterol from the subendothelial intima back to the circulating blood inhibits atherosclerosis development; however