Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Emmanuel Saridakis"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16336 (2023)
Currently, X-ray crystallography, which typically uses synchrotron sources, remains the dominant method for structural determination of proteins and other biomolecules. However, small protein crystals do not provide sufficiently high-resolution diffr
Externí odkaz:
https://doaj.org/article/49a222f6717d430e811772b9378a9636
Autor:
Emmanuel Saridakis, Rishi Vishwakarma, Josephine Lai-Kee-Him, Kevin Martin, Isabelle Simon, Martin Cohen-Gonsaud, Franck Coste, Patrick Bron, Emmanuel Margeat, Marc Boudvillain
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
Cryo-EM shows that M. tuberculosis Rho-factor adopts an open, ring-shaped hexamer conformation and a steric bulk in the cavity for bicyclomycin binding, which explains resistance to the antibiotic.
Externí odkaz:
https://doaj.org/article/552c04a03b95461e80322dd146a3170a
Autor:
Lata Govada, Emmanuel Saridakis, Sean C. Kassen, Ahmad Bin-Ramzi, Rhodri Marc Morgan, Benjamin Chain, John R. Helliwell, Naomi E. Chayen
Publikováno v:
IUCrJ, Vol 8, Iss 4, Pp 678-683 (2021)
C-C chemokine receptor 5 (CCR5) is a major co-receptor molecule used by HIV-1 to enter cells. This led to the hypothesis that stimulating an antibody response would block HIV with minimal toxicity. Here, X-ray crystallographic studies of the anti-CCR
Externí odkaz:
https://doaj.org/article/9d9a11fc926f453ebb082e66a0cece04
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10676 (2022)
Well-diffracting protein crystals are indispensable for X-ray diffraction analysis, which is still the most powerful method for structure-function studies of biomolecules. A promising approach to growing such crystals is the use of porous nucleation-
Externí odkaz:
https://doaj.org/article/2b569b8a44a347958219df46dc0f4b02
Publikováno v:
Universe, Vol 8, Iss 8, p 415 (2022)
General Relativity is a theory of gravity that describes some of the effects of gravity with high accuracy, such as solar system tests, gravitational lensing, gravitational waves, black holes, deflection angle, etc [...]
Externí odkaz:
https://doaj.org/article/81c2b6ca18ed4fbab3f035cfc2529fc5
Autor:
Lukas S Stelzl, Despoina AI Mavridou, Emmanuel Saridakis, Diego Gonzalez, Andrew J Baldwin, Stuart J Ferguson, Mark SP Sansom, Christina Redfield
Publikováno v:
eLife, Vol 9 (2020)
Local structural frustration, the existence of mutually exclusive competing interactions, may explain why some proteins are dynamic while others are rigid. Frustration is thought to underpin biomolecular recognition and the flexibility of protein-bin
Externí odkaz:
https://doaj.org/article/91b2903dba754d03b967a55ca869e844
Publikováno v:
Nature Astronomy. 6:1353-1355
The theme of tensions in cosmology has become increasingly important in the cosmological community, proving capable of attracting new generations of scientists who want to be there and contribute to the next paradigm shift.
Comment: 3 pages, 1 f
Comment: 3 pages, 1 f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315be6cc5e5332a5433ae88f7e5d87dc
https://doi.org/10.1038/s41550-022-01852-3
https://doi.org/10.1038/s41550-022-01852-3
Publikováno v:
Physical Review D. 106
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48ce557d4cdfcf3334bf4dd33ed8d045
https://doi.org/10.1103/physrevd.106.124012
https://doi.org/10.1103/physrevd.106.124012
Publikováno v:
Physical Review D. 106
We present a unified description of the matter and dark energy epochs, using a class of scalar-torsion theories. We provide a Hamiltonian description, and by applying Noether's theorem and by requiring the field equations to admit linear-in-momentum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686e856197c5b03c46ef603ab1008a1c
https://doi.org/10.1103/physrevd.106.024055
https://doi.org/10.1103/physrevd.106.024055