Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Emmanuel Rossy"'
Publikováno v:
Drugs in R&D, Vol 19, Iss 2, Pp 127-140 (2019)
Abstract Objective PF-06438179/GP1111 (PF-SZ-IFX) is an infliximab biosimilar. We evaluated the extended in-use physicochemical and biological stability of PF-SZ-IFX upon preparation for intravenous infusion. Methods Two batches of PF-SZ-IFX were rec
Externí odkaz:
https://doaj.org/article/8a76a108db784f8aa23f4e1e818c5e63
Autor:
Thomas V. Murray, Kasia Kozakowska-McDonnell, Adam Tibbles, Annabel Taylor, Daniel Higazi, Emmanuel Rossy, Alessandra Rossi, Sivaneswary Genapathy, Giulia Tamburrino, Nicola Rath, Natalie Tigue, Vivian Lindo, Tristan Vaughan, Monika A. Papworth
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Bioconjugates are an important class of therapeutic molecules. To date, O-glycan-based metabolic glycoengineering has had limited use in this field, due to the complexities of the endogenous O-glycosylation pathway and the lack of an O-glycosylation
Externí odkaz:
https://doaj.org/article/cf1665fccfe940a89c94acdca72f40c1
Autor:
Vivian Lindo, Sivaneswary Genapathy, Alessandra Rossi, Kasia Kozakowska-McDonnell, Annabel Taylor, Daniel Ramsay Higazi, Papworth Monika, Adam Tibbles, Tristan J Vaughan, Emmanuel Rossy, Giulia Tamburrino, Nicola Rath, Natalie J. Tigue, Murray Thomas Vincent
Publikováno v:
mAbs. 13
Bioconjugates are an important class of therapeutic molecules. To date, O-glycan-based metabolic glycoengineering has had limited use in this field, due to the complexities of the endogenous O-glycosylation pathway and the lack of an O-glycosylation
Autor:
Emmanuel Rossy1, Ludovic Champier1, Beate Bersch2, Bernhard Brutscher2, Martin Blackledge2, Jacques Covès
Publikováno v:
Journal of Biological Inorganic Chemistry (JBIC). Jan2004, Vol. 9 Issue 1, p49-58. 10p.
Autor:
Jacqueline Naylor, Matthieu Chodorge, Tristan J. Vaughan, Jennifer Spooner, Jane K. Osbourn, Jonathan Seaman, Cristina M. Rondinone, Emmanuel Rossy, Nicholas White, Timothy B. C. London, Karen Dickson, Anthony Celeste, David Fairman, Benjamin Kemp, Pia Davidsson, James L. Trevaskis, Andrew Buchanan, Anish Konkar, David C. Hornigold, Lesley Jenkinson, Joseph Grimsby, Nicholas J. Bond
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports
Scientific Reports
Type 2 diabetes (T2D) is a complex and progressive disease requiring polypharmacy to manage hyperglycaemia and cardiovascular risk factors. However, most patients do not achieve combined treatment goals. To address this therapeutic gap, we have devel
Autor:
Regine Landmann, Gennaro De Libero, Emmanuel Rossy, Lucia Mori, Sebastiano Sansano, Hans-Jürgen Gober, Magdalena Kistowska
Publikováno v:
European journal of immunology
Primates, but not rodents, have T cell receptor Vgamma9-Vdelta2 T cells bridging innate and adaptive antimicrobial immunity. This T cell population is activated by prenyl pyrophosphates isolated from microbial or eukaryotic cells. Although the microb
Autor:
Ludovic Champier, Emmanuel Rossy, Jacques Covès, Bernhard Brutscher, Martin Blackledge, Beate Bersch
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 9:49-58
The purified native mercuric reductase (MerA) from Ralstonia metallidurans CH34 contains an N-terminal sequence of 68 amino acids predicted to be homologous to MerP, the periplasmic mercury-binding protein. This MerP-like protein has now been express
Autor:
Gennaro De Libero, Peng George Wang, Jens Schümann, Lizhi Zhu, Wenlan Chen, Emmanuel Rossy, Qingjia Yao, Chengfeng Xia, Wenpeng Zhang
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(8)
Glycoceramides can activate NKT cells by binding with CD1d to produce IFN-gamma, IL-4, and other cytokines. An efficient synthetic pathway for alpha-galactosylceramide (KRN7000) was established by coupling a protected galactose donor to a properly pr
Autor:
Mihai-Constantin S. Ionescu, Lucia Mori, David Cosman, Aleksandra Wodnar-Filipowicz, Pegah Nowbakht, Andreas Rohner, Christian P. Kalberer, Emmanuel Rossy, Gennaro De Libero
Publikováno v:
Blood. 105(9)
Natural killer (NK) cell–mediated cytolytic activity against tumors requires the engagement of activating NK receptors by the tumor-associated ligands. Here, we have studied the role of NKG2D and natural cytotoxicity receptors (NCRs) in the recogni
Autor:
Alexander G. Tonevitsky, Gennaro De Libero, Zaima Mazorra, Martina M. Prendergast, Sebastiano Sansano, Hans Jürgen Gober, Anthony P. Moran, Lucia Mori, Alessandra Sacchi, Silvia Vendetti, Emmanuel Rossy, Abdijapar Shamshiev, Regine Landmann, Olga Chelnokova
Publikováno v:
Immunity. 22(6)
Recognition of self is essential for repertoire selection, immune regulation, and autoimmunity and may be a consequence of infection. Self-induced recognition may represent the escape mechanism adopted by pathogens but may also incite autoimmune dise