Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Emmanuel Ndashimye"'
Autor:
Minh Ha Ngo, Joshua Pankrac, Ryan C. Y. Ho, Emmanuel Ndashimye, Rahul Pawa, Renata Ceccacci, Tsigereda Biru, Abayomi S. Olabode, Katja Klein, Yue Li, Colin Kovacs, Robert Assad, Jeffrey M. Jacobson, David H. Canaday, Stephen Tomusange, Samiri Jamiru, Aggrey Anok, Taddeo Kityamuweesi, Paul Buule, Ronald M. Galiwango, Steven J. Reynolds, Thomas C. Quinn, Andrew D. Redd, Jessica L. Prodger, Jamie F. S. Mann, Eric J. Arts
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTTo date, an affordable, effective treatment for an HIV-1 cure remains only a concept with most “latency reversal” agents (LRAs) lacking specificity for the latent HIV-1 reservoir and failing in early clinical trials. We assessed HIV-1 lat
Externí odkaz:
https://doaj.org/article/c4e48e2d64a24cd4aecbe0e0f13130b6
Publikováno v:
Remote Sensing, Vol 16, Iss 14, p 2509 (2024)
Leveraging weather radar technology for environmental monitoring, particularly the detection of biometeors like birds, bats, and insects, presents a significant challenge due to the dynamic nature of their behavior. Unlike hydrometeor targets, biomet
Externí odkaz:
https://doaj.org/article/6151da60d49f472e90e34509374bd5e7
Autor:
Hannah O. Ajoge, Tyler M. Renner, Kasandra Bélanger, Matthew Greig, Samar Dankar, Hinissan P. Kohio, Macon D. Coleman, Emmanuel Ndashimye, Eric J. Arts, Marc-André Langlois, Stephen D. Barr
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Antiretroviral APOBEC3 may contribute to HIV-1 latency. In this study, Ajoge and Renner et al. identify a previously undescribed function of human APOBEC3 proteins in redirecting integrations of HIV-1 DNA into more transcriptionally inactive regions
Externí odkaz:
https://doaj.org/article/5d4fac7ee2454ce3a9f9906f54abe8e0
Autor:
Sherazaan D. Ismail, Joshua Pankrac, Emmanuel Ndashimye, Jessica L. Prodger, Melissa-Rose Abrahams, Jamie F. S. Mann, Andrew D. Redd, Eric J. Arts
Publikováno v:
Retrovirology, Vol 18, Iss 1, Pp 1-19 (2021)
Abstract HIV-1 persists in infected individuals despite years of antiretroviral therapy (ART), due to the formation of a stable and long-lived latent viral reservoir. Early ART can reduce the latent reservoir and is associated with post-treatment con
Externí odkaz:
https://doaj.org/article/21f8047523904318aa394b0f58bc8bdb
Autor:
Emmanuel Ndashimye, Eric J. Arts
Publikováno v:
International Journal of Infectious Diseases, Vol 105, Iss , Pp 298-303 (2021)
Background: Dolutegravir (DTG) is now recommended to all HIV infected adults, adolescents, and children of right age by WHO. The low cost of $75 per year for generic DTG-based combination, has allowed 3.9 million people living with HIV (PLWH) in low
Externí odkaz:
https://doaj.org/article/6a80ced15af64eb488e67b7b7df5370d
Autor:
Hinissan P. Kohio, Hannah O. Ajoge, Macon D. Coleman, Emmanuel Ndashimye, Richard M. Gibson, Eric J. Arts, Stephen D. Barr
Publikováno v:
Viruses, Vol 15, Iss 2, p 465 (2023)
Retroviral integration site targeting is not random and plays a critical role in expression and long-term survival of the integrated provirus. To better understand the genomic environment surrounding retroviral integration sites, we performed a meta-
Externí odkaz:
https://doaj.org/article/73ba9cd4cd334cb5a56d65d605fc6da5
Autor:
Emmanuel Ndashimye, Eric J. Arts
Publikováno v:
Infectious Diseases of Poverty, Vol 8, Iss 1, Pp 1-8 (2019)
Abstract Background Over 90% of Human Immunodeficiency Virus (HIV) infected individuals will be on treatment by 2020 under UNAIDS 90–90-90 global targets. Under World Health Organisation (WHO) “Treat All” approach, this number will be approxima
Externí odkaz:
https://doaj.org/article/0cf37def71f740e1a7c401bedf99c80c
Autor:
Art F. Y. Poon, Emmanuel Ndashimye, Mariano Avino, Richard Gibson, Cissy Kityo, Fred Kyeyune, Immaculate Nankya, Miguel E. Quiñones-Mateu, Eric J. ARTS, The Ugandan Drug Resistance Study Team
Publikováno v:
AIDS Research and Therapy, Vol 16, Iss 1, Pp 1-10 (2019)
Abstract Background Our understanding of HIV-1 and antiretroviral treatment (ART) is strongly biased towards subtype B, the predominant subtype in North America and western Europe. Efforts to characterize the response to first-line treatments in othe
Externí odkaz:
https://doaj.org/article/13c4971b67a049ee97aed1d41b3aa192
Autor:
Richard M. Gibson, Gabrielle Nickel, Michael Crawford, Fred Kyeyune, Colin Venner, Immaculate Nankya, Eva Nabulime, Emmanuel Ndashimye, Art F. Y. Poon, Robert A. Salata, Cissy Kityo, Peter Mugyenyi, Miguel E. Quiñones-Mateu, Eric J. Arts
Publikováno v:
Infectious Diseases of Poverty, Vol 6, Iss 1, Pp 1-13 (2017)
Abstract Background Thymidine analogs, namely AZT (Zidovudine or Retrovir™) and d4T (Stavudine or Zerit™) are antiretroviral drugs still employed in over 75% of first line combination antiretroviral therapy (cART) in Kampala, Uganda despite avers
Externí odkaz:
https://doaj.org/article/cc1b3016e85046149eaa13ef73e04de9
Autor:
Katja Klein, Gabrielle Nickel, Immaculate Nankya, Fred Kyeyune, Korey Demers, Emmanuel Ndashimye, Cynthia Kwok, Pai-Lien Chen, Sandra Rwambuya, Art Poon, Marshall Munjoma, Tsungai Chipato, Josaphat Byamugisha, Peter Mugyenyi, Robert A Salata, Charles S Morrison, Eric J Arts
Publikováno v:
PLoS Pathogens, Vol 14, Iss 1, p e1006754 (2018)
In the majority of cases, human immunodeficiency virus type 1 (HIV-1) infection is transmitted through sexual intercourse. A single founder virus in the blood of the newly infected donor emerges from a genetic bottleneck, while in rarer instances mul
Externí odkaz:
https://doaj.org/article/7082ff27c4014f5f90eb047f7e4ce0ef