Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Emmanuel Naline"'
Autor:
Camille Roquencourt, Hélène Salvator, Emmanuelle Bardin, Elodie Lamy, Eric Farfour, Emmanuel Naline, Philippe Devillier, Stanislas Grassin-Delyle
Publikováno v:
ERJ Open Research, Vol 9, Iss 5 (2023)
Background Although rapid screening for and diagnosis of coronavirus disease 2019 (COVID-19) are still urgently needed, most current testing methods are long, costly or poorly specific. The objective of the present study was to determine whether or n
Externí odkaz:
https://doaj.org/article/a7ec70aefa0a4b3c8ae3d52cf9048ec9
Autor:
Nikola Mantov, Mathilde Zrounba, Marion Brollo, S Grassin-Delyle, Matthieu Glorion, Mélanie David, Emmanuel Naline, Philippe Devillier, Hélène Salvator
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: The Janus kinase (JAK) 1/2 inhibitor ruxolitinib has been approved in an indication of myelofibrosis and is a candidate for the treatment of a number of inflammatory or autoimmune diseases. We assessed the effects of ruxolitinib on lipopo
Externí odkaz:
https://doaj.org/article/0dfecb0e5b2f4f60965ca8dbb959c020
Autor:
Hélène Salvator, Stanislas Grassin-Delyle, Marion Brollo, Louis-Jean Couderc, Charlotte Abrial, Tatiana Victoni, Emmanuel Naline, Philippe Devillier
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Obesity is associated with an elevated risk of severe respiratory infections and inflammatory lung diseases. The objectives were to investigate 1) the production of adiponectin by human lung explants, 2) the expression of the adiponectin
Externí odkaz:
https://doaj.org/article/487e41bfe6df482785cff29b059f8963
Autor:
Stanislas Grassin-Delyle, Ph.D., Camille Roquencourt, M.S., Pierre Moine, M.D., Gabriel Saffroy, Stanislas Carn, Nicholas Heming, M.D., Jérôme Fleuriet, Ph.D., Hélène Salvator, M.D., Emmanuel Naline, Ph.D., Louis-Jean Couderc, M.D., Philippe Devillier, M.D., Etienne A. Thévenot, Ph.D., Djillali Annane, M.D.
Publikováno v:
EBioMedicine, Vol 63, Iss , Pp 103154- (2021)
Background: Early diagnosis of coronavirus disease 2019 (COVID-19) is of the utmost importance but remains challenging. The objective of the current study was to characterize exhaled breath from mechanically ventilated adults with COVID-19. Methods:
Externí odkaz:
https://doaj.org/article/1c2831184d5349db932ede72b1246b29
Autor:
Hélène Salvator, Amparo Buenestado, Marion Brollo, Emmanuel Naline, Tatiana Victoni, Elisabeth Longchamp, Hermann Tenor, Stanislas Grassin-Delyle, Philippe Devillier
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Background: Roflumilast is an option for treating patients with severe COPD and frequent exacerbations despite optimal therapy with inhaled drugs. The present study focused on whether the phosphodiesterase (PDE) 4 inhibitor roflumilast and its active
Externí odkaz:
https://doaj.org/article/35f2121e1b8d4ebebc14487580452dbb
Autor:
Hélène Salvator, Stanislas Grassin-Delyle, Emmanuel Naline, Marion Brollo, Caroline Fournier, Louis-Jean Couderc, Philippe Devillier
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
BackgroundObesity is associated with an elevated risk of respiratory infections and inflammatory lung diseases. The objective was to investigate (i) the effects of adipokines (adiponectin (APN), leptin, chemerin, and visfatin) on the production of cy
Externí odkaz:
https://doaj.org/article/3b4e4f56e7ae451fa8d93a9841bb05bf
Autor:
Fanta Fall, Elodie Lamy, Marion Brollo, Emmanuel Naline, Natacha Lenuzza, Etienne Thévenot, Philippe Devillier, Stanislas Grassin-Delyle
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0230813 (2020)
Lung macrophages (LM) are in the first line of defense against inhaled pathogens and can undergo phenotypic polarization to the proinflammatory M1 after stimulation with Toll-like receptor agonists. The objective of the present work was to characteri
Externí odkaz:
https://doaj.org/article/835a48466e914a1897cef61a6591c9ed
Autor:
Tatiana Victoni, Hélène Salvator, Charlotte Abrial, Marion Brollo, Luis Cristovão Sobrino Porto, Vincent Lagente, Emmanuel Naline, Stanislas Grassin-Delyle, Philippe Devillier
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-10 (2017)
Abstract Background β2-adrenoceptor agonists have been shown to reduce the lipopolysaccharide (LPS)-induced cytokine release by human monocyte-derived macrophages (MDMs). We compare the expression of β2-adrenoceptors and the inhibitory effect of fo
Externí odkaz:
https://doaj.org/article/ee563f613beb4309b150535514c40dfa
Autor:
Priscilla Henno, Stanislas Grassin-Delyle, Emeline Belle, Marion Brollo, Emmanuel Naline, Edouard Sage, Philippe Devillier, Dominique Israël-Biet
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-8 (2017)
Abstract Background Tobacco-induced pulmonary vascular disease is partly driven by endothelial dysfunction. The Sonic hedgehog (SHH) pathway is involved in vascular physiology. We sought to establish whether the SHH pathway has a role in pulmonary en
Externí odkaz:
https://doaj.org/article/87d1b25e89b0436aa5d1c86c84ab1763
Autor:
Stanislas Grassin-Delyle, Hélène Salvator, Nikola Mantov, Charlotte Abrial, Marion Brollo, Christophe Faisy, Emmanuel Naline, Louis-Jean Couderc, Philippe Devillier
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
BackgroundBitter-taste receptors (TAS2Rs) are involved in airway relaxation but are also expressed in human blood leukocytes. We studied TAS2R expression and the effects of TAS2R agonists on the lipopolysaccharide (LPS)-induced cytokine release in hu
Externí odkaz:
https://doaj.org/article/8a4e272cdd3841ba80d583fea1bc43f1