Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Emmanuel Lefèbvre"'
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Akademický článek
The extreme variety of genotoxic response to benzo[a]pyrene in three different human cell lines from three different organs.
Autor: Camille Genies, Anne Maître, Emmanuel Lefèbvre, Amandine Jullien, Marianne Chopard-Lallier, Thierry Douki
Publikováno v: PLoS ONE, Vol 8, Iss 11, p e78356 (2013)
Polycyclic aromatic hydrocarbons (PAHs) are associated with occupational exposure and urban atmospheric pollution. Determination of the genotoxic properties of these compounds is thus of outmost importance. For this purpose a variety of cellular mode
Externí odkaz: https://doaj.org/article/81286c27129345a5988c73fbd7e98cb6
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2
Oxidative stress and DNA damage induced by cadmium in the human keratinocyte HaCaT cell line: Role of glutathione in the resistance to cadmium
Autor: Pascale Guiraud, Emmanuel Lefèbvre, Yves Nzengue, Catherine Garrel, Régine Steiman
Publikováno v: Toxicology. 243:193-206
Cadmium affects the cellular homeostasis and generates damage via complex mechanisms involving interactions with other metals and oxidative stress induction. In this work we used a human keratinocyte cell line (HaCaT) as a model to study the oxidativ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c880465fb2d1ccab3657a15b590b6f9
https://doi.org/10.1016/j.tox.2007.10.005
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3
The Extreme Variety of Genotoxic Response to Benzo[a]pyrene in Three Different Human Cell Lines from Three Different Organs
Autor: Marianne Chopard-Lallier, Amandine Jullien, Emmanuel Lefèbvre, Camille Genies, Anne Maitre, Thierry Douki
Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2013, 8 (11), ⟨10.1371/journal.pone.0078356⟩
PLoS ONE, 2013, 8 (11), ⟨10.1371/journal.pone.0078356⟩
PLoS ONE, Vol 8, Iss 11, p e78356 (2013)
Polycyclic aromatic hydrocarbons (PAHs) are associated with occupational exposure and urban atmospheric pollution. Determination of the genotoxic properties of these compounds is thus of outmost importance. For this purpose a variety of cellular mode
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e5f47770e3208a5113d9f108a6e193
https://hal.archives-ouvertes.fr/hal-01903135
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4
Polycyclic aromatic hydrocarbons in binary mixtures modulate the efficiency of benzo[a]pyrene to form DNA adducts in human cells
Autor: Thierry Douki, Emmanuel Lefèbvre, Afef Rajhi, Anne Maitre, Adeline Tarantini, Marie Marques
Publikováno v: Toxicology
Toxicology, 2011, 279 (1-3), pp.36-44. ⟨10.1016/j.tox.2010.09.002⟩
Toxicology, Elsevier, 2011, 279 (1-3), pp.36-44. ⟨10.1016/j.tox.2010.09.002⟩
Exposure to polycyclic aromatic hydrocarbons (PAHs) always involves complex mixtures that may induce synergistic or antagonistic effects on the genotoxic properties and make risk assessment more difficult. In this study, we evaluated how particulate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad7ce426608135fd8f078fe5a4f2b4f
https://hal.science/hal-01903180
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5
Relative contribution of DNA strand breaks and DNA adducts to the genotoxicity of benzo[a]pyrene as a pure compound and in complex mixtures
Autor: Emmanuel Lefèbvre, Jean-Luc Ravanat, Adeline Tarantini, Anne Maitre, Marie Marques, Thierry Douki, Caroline Marie
Publikováno v: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2009, 671 (1-2), pp.67-75. ⟨10.1016/j.mrfmmm.2009.08.014⟩
Polycyclic aromatic hydrocarbons (PAH) produced upon incomplete combustion of organic matter are suspected to be carcinogenic to humans. In the present work, we especially studied the genotoxicity of benzo[a]pyrene (B[a]P), pure or in mixtures, with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a360d01176b913eab24ec3a2c16ec34
https://hal.science/hal-01903200
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6
Metallothionein expression in HaCaT and C6 cell lines exposed to cadmium
Autor: Walid Rachidi, Alain Favier, Pascale Guiraud, Régine Steiman, Jean Cadet, Yves Nzengue, Emmanuel Lefèbvre
Publikováno v: Journal of Trace Elements in Medicine and Biology
Journal of Trace Elements in Medicine and Biology, Elsevier, 2009, 23 (4), pp.314--323. ⟨10.1016/j.jtemb.2009.05.005⟩
Journal of Trace Elements in Medicine and Biology, 2009, 23 (4), pp.314--323. ⟨10.1016/j.jtemb.2009.05.005⟩
International audience; Metallothioneins (MT) are low-molecular weight, cysteine-rich metal-binding proteins. MT play a role in the homeostasis of essential metals such as zinc (Zn) and copper (Cu), detoxification of toxic metals such as cadmium (Cd)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b0ebc7e284ac8edebc993d5782255f
https://pubmed.ncbi.nlm.nih.gov/19747627
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