Exploration of the effects of chloride ions on the analysis of polar compounds at low concentrations by hydrophilic interaction liquid chromatography coupled to a charged aerosol detector: Application to tromethamine

Autor: Balthazar Toussaint, Taslyne Immame Hassane Beck, Estelle Surget, Vincent Boudy, Emmanuel Jaccoulet

Publikováno v: Journal of Separation Science. 46

In this study, we discuss the origin of the slightly increased response of the charged aerosol detector when low-concentration polar drugs formulated with sodium chloride are analyzed by hydrophilic interaction liquid chromatography coupled to the ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1fb5e23c1149dc1e27642067ca9b16
https://doi.org/10.1002/jssc.202200766

Understanding the retention mechanisms of a reversed-phase/anion exchange/cation-exchange column for the separation of epinephrine and norepinephrine

Autor: Jean-Baptiste Mattioni, Christel de la Reberdière, Vincent Boudy, Emmanuel Jaccoulet

Publikováno v: Journal of Pharmaceutical and Biomedical Analysis. 227:115273

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f811beb4d1be2442b2af80eb6bfe6f8
https://doi.org/10.1016/j.jpba.2023.115273

Investigation of hydrophilic interaction liquid chromatography coupled with charged aerosol detector for the analysis of tromethamine

Autor: Christine Herrenknecht, Emmanuel Jaccoulet, Vincent Boudy, Estelle Surget, Taslyne Imame Hassane Beck, Balthazar Toussaint

Publikováno v: Talanta. 238:123050

Tromethamine (TMM), often encountered in a final drug product, exhibits interesting chemical properties as a counter ion, buffer, or active ingredient. European and US pharmacopeias propose titration against hydrogen chloride for TMM assays. However,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741302cfe7febf2d54cd22ef181610a3
https://doi.org/10.1016/j.talanta.2021.123050

A centralized automated-dispensing system in a French teaching hospital: return on investment and quality improvement

Autor: Brigitte Sabatier, Patrice Prognon, Emmanuel Jaccoulet, Laetitia Minh Mai Lê, Vincent Zaugg, Sarah Berdot, Virginie Korb-Savoldelli

Publikováno v: International Journal for Quality in Health Care
International Journal for Quality in Health Care, Oxford University Press (OUP), 2019, 31 (3), pp.219-224. ⟨10.1093/intqhc/mzy152⟩
International Journal for Quality in Health Care, 2019, 31 (3), pp.219-224. ⟨10.1093/intqhc/mzy152⟩

International audience; Objectives: To evaluate the return on investment (ROI) and quality improvement after implementation of a centralized automated-dispensing system after 8 years of use.Design: Prospective evaluation of ROI; before and after stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8c5728b76a52a2a76cc13c92c17f05
https://doi.org/10.1093/intqhc/mzy152

Forced Degradation of Monoclonal Antibodies After Compounding: Impact on Routine Hospital Quality Control

Autor: Patrice Prognon, Eric Caudron, Thomas Daniel, Emmanuel Jaccoulet

Publikováno v: Journal of Pharmaceutical Sciences-Elsevier
Journal of Pharmaceutical Sciences-Elsevier, Elsevier, 2019, 108, pp.3252-3261. ⟨10.1016/j.xphs.2019.06.004⟩

Compounded therapeutic mAbs used in a hospital require quality control (QC). In our hospital, analytical QC process intended to mAbs identification and quantification is based on flow injection analysis associated with second-derivative UV spectrosco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c9ee7a0e668e880feb4d43772174dd
https://hal.archives-ouvertes.fr/hal-03487643/file/S0022354919303727.pdf