Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Emmanuel Israel Edache"'
Autor:
Victor Onukwube Apeh, Kennedy Chinedu Okafor, Ifeoma Felicia Chukwuma, Henrietta Onyinye Uzoeto, Titus Ifeanyi Chinebu, Florence Nkechi Nworah, Emmanuel Israel Edache, Ijeoma Peace Okafor, Okoronkwo Chukwunenye Anthony
Publikováno v:
Engineering Reports, Vol 6, Iss 9, Pp n/a-n/a (2024)
Abstract The emergence of resistance to current antimalarial drugs poses a significant challenge in the fight against malaria. This study aimed to investigate the in vivo antiplasmodial potential of the aqueous extract of fresh and dried leaves of A3
Externí odkaz:
https://doaj.org/article/95ffd1c14a0548f681011d1a5f189611
Autor:
Emmanuel Israel Edache, Adamu Uzairu, Paul Andrew Mamza, Gideon Adamu Shallangwa, Fatma Hilal Yagin, Nagwan Abdel Samee, Noha F. Mahmoud
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
The development of novel medicines to treat autoimmune diseases and SARS-CoV-2 main protease (Mpro), a virus that can cause both acute and chronic illnesses, is an ongoing necessity for the global community. The primary objective of this research is
Externí odkaz:
https://doaj.org/article/f3514e3f383f41f5982a5a9da53f7e7f
Publikováno v:
Borneo Journal of Pharmacy, Vol 6, Iss 3 (2023)
Graves' disease (GD) is an autoimmune condition that frequently causes hyperthyroidism and thyrotoxicosis. Protein tyrosine phosphatase, non-receptor type 22 (lymphoid) isoform 1 (PTPN22), is a promising therapeutic candidate for treating Graves' dis
Externí odkaz:
https://doaj.org/article/c7970fcd16f04082a9c88ee4041eb2c9
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background In seek of potent and non-toxic iminoguanidine derivatives formerly assessed as active Pseudomonas aeruginosa inhibitors, a combined mathematical approach of quantitative structure-activity relationship (QSAR), homology modeling,
Externí odkaz:
https://doaj.org/article/ec87e82bf389406b96d3ae982b79287e
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 7, Iss 1, Pp 1-22 (2021)
Abstract Background The most frequent bacterial sexually transmitted disease is Chlamydia trachomatis (STD). In 2010, the Centers for Disease Control and Prevention (CDC) received 1.3 million reports of cases (CDC). Human chlamydial infections are li
Externí odkaz:
https://doaj.org/article/43d37be5661542e6979177b6f5914c36
Publikováno v:
Scientific African, Vol 15, Iss , Pp e01088- (2022)
Rheumatoid arthritis (RA) is an autoimmune condition in the world, affecting about 1% of the population. It is characterized by a cartilage attack unique to the tissue in the peripheral joints. Different types of drugs are used to treat the disease a
Externí odkaz:
https://doaj.org/article/46b75bc43c8346719d18040de6e61a2e
Autor:
Emmanuel Israel Edache
Publikováno v:
Journal of Virology and Viral Diseases. 2:1-28
Pseudomonas aeruginosa and SARS-CoV-2 are two of the world's most hazardous diseases. Treatments that target the enzyme or protein could be more successful and efficient. In this study, iminoguanidine derivatives were treated to a combination of five
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8b5fcb4c74d1d9c1876fdd29cedf4fb
https://doi.org/10.54289/jvvd2200106
https://doi.org/10.54289/jvvd2200106
Publikováno v:
Journal of the Mexican Chemical Society. 66
The investigation for innovative treatments for Pseudomonas aeruginosa and SARS-CoV-2 is a burgeoning field. Even though scientists and pharmaceutical companies have made significant contributions to the research of multi-drug resistance infections f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b75c7fa48dc0bb8b2651adc2ea5ba58
https://doi.org/10.29356/jmcs.v66i4.1726
https://doi.org/10.29356/jmcs.v66i4.1726
Publikováno v:
Journal of Drugs and Pharmaceutical Science. 4:21-36
QSAR models of 25 iminoguanidine derivatives with inhibitory HemO were developed. The QSAR model was built by using DFT-MLR and the best QSAR model has R2, Q2 values of 0.6569 and 0.5493 for cross-validated and non-cross-validated. The predictive abi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7926f624e686a6dd0ac36cb6bcd79377
https://doi.org/10.31248/jdps2020.036
https://doi.org/10.31248/jdps2020.036
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 7, Iss 1, Pp 1-22 (2021)
Background The most frequent bacterial sexually transmitted disease is Chlamydia trachomatis (STD). In 2010, the Centers for Disease Control and Prevention (CDC) received 1.3 million reports of cases (CDC). Human chlamydial infections are linked to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1621b34d06a8d650adba1879959df8de
https://doi.org/10.1186/s43094-021-00367-4
https://doi.org/10.1186/s43094-021-00367-4