Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Emmanuel H. Demont"'
Autor:
Catherine M. Alder, Matthew Gray, Chelsea A. Huff, Calvin O. Manning, Alex Preston, Philip Rushworth, Leanna E. Shuster, Robert J. Watson, Katherine M. P. Wheelhouse, Glynn D. Williams, Emmanuel H. Demont
Publikováno v:
Organic Process Research & Development. 26:365-379
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b9ba00414e3f2b623622d2efc73c263
https://doi.org/10.1021/acs.oprd.1c00422
https://doi.org/10.1021/acs.oprd.1c00422
Autor:
Lee A, Harrison, Stephen J, Atkinson, Anna, Bassil, Chun-Wa, Chung, Paola, Grandi, James R J, Gray, Etienne, Levernier, Antonia, Lewis, David, Lugo, Cassie, Messenger, Anne-Marie, Michon, Darren J, Mitchell, Alex, Preston, Rab K, Prinjha, Inmaculada, Rioja, Jonathan T, Seal, Simon, Taylor, Ian D, Wall, Robert J, Watson, James M, Woolven, Emmanuel H, Demont
Publikováno v:
Journal of medicinal chemistry. 64(15)
Domain-specific BET bromodomain ligands represent an attractive target for drug discovery with the potential to unlock the therapeutic benefits of antagonizing these proteins without eliciting the toxicological aspects seen with pan-BET inhibitors. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29838ca81add590d8ccf661d7c0b5e04
https://pubmed.ncbi.nlm.nih.gov/34232650
https://pubmed.ncbi.nlm.nih.gov/34232650
Autor:
Alex, Preston, Stephen, Atkinson, Paul, Bamborough, Chun-Wa, Chung, Peter D, Craggs, Laurie, Gordon, Paola, Grandi, James R J, Gray, Emma J, Jones, Matthew, Lindon, Anne-Marie, Michon, Darren J, Mitchell, Rab K, Prinjha, Francesco, Rianjongdee, Inmaculada, Rioja, Jonathan, Seal, Simon, Taylor, Ian, Wall, Robert J, Watson, James, Woolven, Emmanuel H, Demont
Publikováno v:
Journal of medicinal chemistry. 63(17)
Pan-bromodomain and extra terminal domain (BET) inhibitors interact equipotently with the eight bromodomains of the BET family of proteins and have shown profound efficacy in a number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4046d324ecd8b85a10f0784785606a9e
https://pubmed.ncbi.nlm.nih.gov/32691591
https://pubmed.ncbi.nlm.nih.gov/32691591
Autor:
Catherine M. Alder, Matthew Gray, Chelsea A. Huff, Calvin O. Manning, Alex Preston, Philip Rushworth, Leanna E. Shuster, Robert J. Watson, Katherine M. P. Wheelhouse, Glynn D. Williams, Emmanuel H. Demont
Publikováno v:
Organic Process Research & Development. 26:1341-1341
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7571814d577501468b37ad467f47e1e
https://doi.org/10.1021/acs.oprd.2c00068
https://doi.org/10.1021/acs.oprd.2c00068
Autor:
Paul Bamborough, Chun-wa Chung, RebeccaC. Furze, Paola Grandi, Anne-Marie Michon, Robert J. Sheppard, Heather Barnett, Hawa Diallo, DavidP. Dixon, Clement Douault, Emma J. Jones, Bhumika Karamshi, Darren J. Mitchell, Rab K. Prinjha, Christina Rau, RobertJ. Watson, Thilo Werner, Emmanuel H. Demont
Publikováno v:
Journal of Medicinal Chemistry; Aug2015, Vol. 58 Issue 15, p6151-6178, 28p
Autor:
Emmanuel H. Demont, Chun-wa Chung, RebeccaC. Furze, Paola Grandi, Anne-Marie Michon, Chris Wellaway, Nathalie Barrett, Angela M. Bridges, PeterD. Craggs, Hawa Diallo, David P. Dixon, Clement Douault, Amanda J. Emmons, EmmaJ. Jones, Bhumika V. Karamshi, Kelly Locke, Darren J. Mitchell, BernadetteH. Mouzon, Rab K. Prinjha, Andy D. Roberts
Publikováno v:
Journal of Medicinal Chemistry; Jul2015, Vol. 58 Issue 14, p5649-5673, 25p