Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Emmanuel E Baetge"'
Autor:
Thomas C Schulz, Holly Y Young, Alan D Agulnick, M Josephine Babin, Emmanuel E Baetge, Anne G Bang, Anindita Bhoumik, Igor Cepa, Rosemary M Cesario, Carl Haakmeester, Kuniko Kadoya, Jonathan R Kelly, Justin Kerr, Laura A Martinson, Amanda B McLean, Mark A Moorman, Janice K Payne, Mike Richardson, Kelly G Ross, Eric S Sherrer, Xuehong Song, Alistair Z Wilson, Eugene P Brandon, Chad E Green, Evert J Kroon, Olivia G Kelly, Kevin A D'Amour, Allan J Robins
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37004 (2012)
Development of a human embryonic stem cell (hESC)-based therapy for type 1 diabetes will require the translation of proof-of-principle concepts into a scalable, controlled, and regulated cell manufacturing process. We have previously demonstrated tha
Externí odkaz:
https://doaj.org/article/217b85207ea64dde8656ee24573940b2
Publikováno v:
Nestle Nutrition Institute workshop series. 84
Nutritional research is entering a paradigm shift which necessitates the modeling of complex interactions between diet, genetics, lifestyle, and environmental factors. This requires the development of analytical and processing capabilities for multip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ce8aa3d28b0dcf613d843aa96bdb014
https://pubmed.ncbi.nlm.nih.gov/26764480
https://pubmed.ncbi.nlm.nih.gov/26764480
Autor:
Emmanuel E, Baetge
Publikováno v:
Nestle Nutrition Institute workshop series. 84
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c6bd3d637cfc1db35e71c87b2acfe21c
https://pubmed.ncbi.nlm.nih.gov/26764481
https://pubmed.ncbi.nlm.nih.gov/26764481
Nutritional research is entering a paradigm shift which necessitates the modeling of complex interactions between diet, genetics, lifestyle, and environmental factors. This requires the development of analytical and processing capabilities for multip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e517594de2384ab4d0ed073b7cae1818
https://doi.org/10.1159/000436995
https://doi.org/10.1159/000436995
Autor:
Justine J Cunningham, Mike Richardson, Kuniko Kadoya, Nora G. Smart, Melissa K. Carpenter, Susan Eliazer, Holly Y. Young, Emmanuel E. Baetge, Anne G. Bang, Olivia Kelly, Evert Kroon, Alan D. Agulnick, Laura Martinson, Kevin A. D'Amour
Publikováno v:
Nature Biotechnology. 26:443-452
Development of a cell therapy for diabetes would be greatly aided by a renewable supply of human β-cells. Here we show that pancreatic endoderm derived from human embryonic stem (hES) cells efficiently generates glucose-responsive endocrine cells af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c2264a079324d8e12ea8bed61c0ef3
https://doi.org/10.1038/nbt1393
https://doi.org/10.1038/nbt1393
Autor:
Alan D. Agulnick, Melissa K Carpenter, Susan Eliazer, Mark A. Moorman, Anne G. Bang, Olivia Kelly, Evert Kroon, Emmanuel E. Baetge, Kevin A. D'Amour, Nora G Smart
Publikováno v:
Nature Biotechnology. 24:1392-1401
Of paramount importance for the development of cell therapies to treat diabetes is the production of sufficient numbers of pancreatic endocrine cells that function similarly to primary islets. We have developed a differentiation process that converts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b73d3cb0d8bcc6fd87e953960e927f4f
https://doi.org/10.1038/nbt1259
https://doi.org/10.1038/nbt1259
Autor:
Kuniko Kadoya, Gregory L. Szot, Justin Kerr, Jiena Lang, Evert Kroon, Emmanuel E. Baetge, Mahesh Yadav, Hélène Bour-Jordan, Jeffrey A. Bluestone, Eugene P. Brandon
Publikováno v:
Cell Stem Cell
SummaryType 1 diabetes (T1D) is an autoimmune disease caused by T cell-mediated destruction of insulin-producing β cells in the islets of Langerhans. In most cases, reversal of disease would require strategies combining islet cell replacement with i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4beca1abc3022c61626e1279d4c6d4a9
https://pubmed.ncbi.nlm.nih.gov/25533131
https://pubmed.ncbi.nlm.nih.gov/25533131
Autor:
Kevin A. D'Amour, Kelly G. Ross, Laura Martinson, Evert Kroon, Mike Richardson, Mark A. Moorman, Melissa K. Carpenter, Traci M Ostertag, Emmanuel E. Baetge, Man Yin Chan, Anne G. Bang, Kuniko Kadoya, Olivia Kelly
Publikováno v:
Nature biotechnology. 29(8)
Using a flow cytometry-based screen of commercial antibodies, we have identified cell-surface markers for the separation of pancreatic cell types derived from human embryonic stem (hES) cells. We show enrichment of pancreatic endoderm cells using CD1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d641968d60845160813b45bd6462eb
https://pubmed.ncbi.nlm.nih.gov/21804561
https://pubmed.ncbi.nlm.nih.gov/21804561
Publikováno v:
Clinical science (London, England : 1979). 118(2)
With the already heightened demand placed on organ donation, stem cell therapy has become a tantalizing idea to provide glucose-responsive insulin-producing cells to Type 1 diabetic patients as an alternative to islet transplantation. Multiple groups
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9eb7dfe5088c1e215fba7e4b9c4192
https://pubmed.ncbi.nlm.nih.gov/19807695
https://pubmed.ncbi.nlm.nih.gov/19807695
Autor:
Amanda B. McLean, Alan M Sheppard, Stephen Dalton, Huiqing Liu, Michael Kulik, Emmanuel E. Baetge, Malini Krishnamoorthy, David Reynolds, Ying Xu, Karen Louise Jones, Kevin A. D'Amour
Publikováno v:
Stem cells (Dayton, Ohio). 25(1)
Human ESCs (hESCs) respond to signals that determine their pluripotency, proliferation, survival, and differentiation status. In this report, we demonstrate that phosphatidylinositol 3-kinase (PI3K) antagonizes the ability of hESCs to differentiate i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40dfb64a151d6f09aeb1420e955a8b14
https://pubmed.ncbi.nlm.nih.gov/17204604
https://pubmed.ncbi.nlm.nih.gov/17204604